2013 Incidence Rate of Breast Cancer in Young Women
” At a time when the USA is making progress overall against cancer, a new study documents a worrisome rise in the number of young women diagnosed with advanced, incurable breast cancer.
The number of American women ages 25 to 39 diagnosed with metastatic breast cancer — which has already spread to other organs by the time it’s found — rose about 3.6% a year from 2000 to 2009, according to a study – Incidence Rate of Breast Cancer in Young Women – in today’s Journal of the American Medical Association. ”
Women’s Exposures early in Life could unlock Mysteries
” When Ida Washington received a letter inviting her to participate in a women’s health study to explore the environmental roots of breast cancer, she didn’t think twice. Her mother was diagnosed with the disease nearly 40 years ago, and since then, it has been a terrifying mystery she has yearned to unravel.
Washington was just a teenager when the lump was found on her mother’s left breast. In the years that followed, as her mother’s cancer went into remission, she began to wonder what caused it. “My mother didn’t smoke, she didn’t drink. Breast cancer didn’t run in the family,” she said
Ida’s mother, Willie Mae Washington, now 92, participated in the first generation of a scientific study that has endured for more than half a century to investigate whether environmental exposures may trigger breast cancer. Now Ida Washington, 52, is continuing the legacy as part of its second generation.
The two women are among the more than 15,000 mothers, daughters and granddaughters in the San Francisco Bay Area enrolled in a project known as the Child Health and Development Studies, launched in 1959. Tens of thousands of samples of the women’s blood are stored, providing more than 50 years of continuous data on health outcomes and environmental exposures.
Scientists tap into this unique trove as they struggle to figure out what role environmental exposures play in the development of diseases such as breast cancer. ” …
… Continue reading Breast cancer and the environment Part 2: Studied for half a century, these women are ‘a national treasure’, environmentalhealthnews, Feb. 26, 2013.
Studied for half a Century, these Women are “a National Treasure”
” Deep in a laboratory freezer, 100,000 vials of blood have been frozen for the better part of five decades.
For scientist Barbara Cohn, it’s a treasure trove. Collected from more than 15,000 San Francisco Bay Area women after they gave birth in the 1960s, each vial of blood holds a woman’s lifetime of secrets.
Scientists say these vials could help them unravel one of the most enduring medical mysteries: Why do some women, with no family history, develop breast cancer?
The blood bears the chemical signature of environmental pollutants, some long banned, that the women were exposed to decades ago. Cohn, who directs the research in Berkeley, Calif., believes these early-life exposures may hold the key to understanding a woman’s risk of breast cancer today.
The women’s blood is being tested for traces of dozens of pollutants – used by industry and found in many consumer products – that can impersonate estrogen and other hormones. The theory is that early exposure to these chemicals, even before birth, inside the mother’s womb, may fundamentally alter the way that breast tissues grow, triggering cancer decades later.
Cancer patients and their doctors have long puzzled over what factors in a woman’s environment may raise her risk of breast cancer. One of every eight women in the United States is diagnosed with breast cancer during her lifetime, with more than 232,000 new cases diagnosed yearly, according to the American Cancer Society. Only 5 to 10 percent can be accounted for by genetics; other known risk factors include age, obesity and low physical activity. ” …
… Continue reading Breast cancer and the environment Part 1: Women’s exposures early in life could unlock mysteries, environmentalhealthnews, Feb. 26, 2013.
“The Boston University researchers compared the age of menopause of 4,800 ‘DES daughters‘ with that of more 2,100 women whose mothers had not taken the drug. The DES daughters were 50 per cent more likely to have reached menopause early. And the more DES their mothers had taken, the greater the risk. Worst affected were those whose mothers had taken part in a DES trial in the Fifties ? these women were twice as likely to have reached menopause as others their age. “
Read Pregnancy drug linked to an early menopause, Daily Mail, August 2006.
2012: deux laboratoires condamnés à indemniser une victime DES
Demuis 2009 en France, lorsque l’exposition à l’hormone de synthèse DES est établie, il revient aux laboratoires de prouver que leur médicament n’était pas en cause, et non aux femmes de déterminer quel produit exactement était en cause.
Lire Distilbène : deux laboratoires condamnés à indemniser une victime, Le Monde, 26.10.2012
2012 – The inventor of Thalidomide, the Grunenthal Group, released a statement saying it “regrets” the consequences of the drug
Launched as a drug for treating morning sickness, Thalidomide unexpectedly gave rise to severe abnormalities in children It has taken half a century for the victims of birth defect pregnancy drug Thalidomide to receive an apology from its German inventors.