“ This month, Johnson & Johnson is facing more than 10,000 lawsuits over an artificial hip that has been recalled because of a 40 percent failure rate within five years. Mistakes happen in medicine, but internal documents showed that executives had known of flaws with the device for some time, but had failed to make them public “
mmm… sounds familiar Eli Lilly !
Read Health Care’s Trick Coin by Ben Goldacre, a doctor, author of “Bad Pharma”. It’s Time for Actions: did you SIGN THE PETITION ?
New research is adding to the evidence that some pesticides and industrial chemicals may increase women’s risk of uterine and ovarian diseases, such as endometriosis.
Read Gynecological Diseases Linked to Environmental Contaminants
Read more about Endocrine disruptors
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Risky pregnancy drug raised daughters’ cancer odds
‘ A drug that millions of pregnant women took decades ago to prevent miscarriage and complications has put their daughters at higher risk for breast cancer and other health problems that are showing up now, a new federal study finds. ‘
Read Risky pregnancy drug raised daughters’ cancer odds
More DES DiEthylStilbestrol Resources
IVF does not boost cancer risk, study finds
DES Action USA commented:
“ This study will be reassuring for those who’ve undergone IVF. But it’s difficult to rest completely reassured knowing all the hormones used in fertility treatments.
Not clear whether DES exposure changes the equation any. “
Read IVF does not boost cancer risk, study finds
Sadly for many DES daughters having their own children is not possible! Many of us who have experienced miscarriages, want to have kids but are struggling or unable to…
A lire surtout si votre mère ou grand-mère s’en sont vues prescrire pendant leur grossesse…
Connaissant les risques auxquels avec le DES ils exposaient les femmes – au moins sur une génération – les pouvoirs publics l’ont autorisé et des médecins l’ont largement prescrit pendant 5 à 12 ans dans ces 7 pays…
Le DES fut arrêté chez les femmes enceintes :
- en 71 aux USA.
- en 76, soit 5 ans après ! au Canada.
- en 77, soit 6 ans après ! en France, Autriche, Pays-bas.
- en 78, soit 8 ans après ! en Australie.
- en 81, soit 11 ans après ! en Italie.
- en 83, soit 12 ans après ! en Hongrie.
Utilisé par le suite comme “pilule du lendemain“, il est encore utilisé en Afrique pour provoquer un avortement (2013).
Le Distilbène DES, en savoir plus
Federal Judge Allows Lawsuit Against Anti-Miscarriage Drugs for Cancer Link
“ Magistrate Judge Marianne B. Bowler denied the motion to dismiss made by the drug companies. The drug companies argued that the opinions of the women’s experts were not based on reliable science; the judge did not agree, and is allowing the case to move forward “ .
Read Federal Judge Allows Lawsuit Against Anti-Miscarriage Drugs for Cancer Link .
It’s Time for Actions: did you SIGN THE PETITION ?
More DES DiEthylStilbestrol Resources
What gives you strength? My daughters give me the strength to cut through the wall of silence around the DES issues … Image via A Major Media.
Gestational exposure to bisphenol a produces transgenerational changes in behaviors and gene expression
Bisphenol-A BPA, DES and similar compounds are known as endocrine-disrupting chemicals, which are substances in the environment that interfere with the proper functioning of hormones.
Bisphenol A (BPA) is a plasticizer and an endocrine-disrupting chemical. It is present in a variety of products used daily including food containers, paper, and dental sealants and is now widely detected in human urine and blood. Exposure to BPA during development may affect brain organization and behavior, perhaps as a consequence of its actions as a steroid hormone agonist/antagonist and/or an epigenetic modifier. Here we show that BPA produces transgenerational alterations in genes and behavior. Female mice received phytoestrogen-free chow with or without BPA before mating and throughout gestation. Plasma levels of BPA in supplemented dams were in a range similar to those measured in humans. Juveniles in the first generation exposed to BPA in utero displayed fewer social interactions as compared with control mice, whereas in later generations (F(2) and F(4)), the effect of BPA was to increase these social interactions. Brains from embryos (embryonic d 18.5) exposed to BPA had lower gene transcript levels for several estrogen receptors, oxytocin, and vasopressin as compared with controls; decreased vasopressin mRNA persisted into the F(4) generation, at which time oxytocin was also reduced but only in males. Thus, exposure to a low dose of BPA, only during gestation, has immediate and long-lasting, transgenerational effects on mRNA in brain and social behaviors. Heritable effects of an endocrine-disrupting chemical have implications for complex neurological diseases and highlight the importance of considering gene-environment interactions in the etiology of complex disease.
Sources and more information
- Gestational exposure to bisphenol a produces transgenerational changes in behaviors and gene expression, Endocrinology. 2012 Aug;153(8):3828-38. doi: 10.1210/en.2012-1195. PMID: 22707478 Epub 2012 Jun 15. Full text.
- BPA Exposure Effects May Last for Generations, Endocrine Society, press-release-archives/2012.