Perturbateurs Endocriniens et Troubles du Comportement, Témoignages et Recherche Scientifique

Nous n’avons pas encore tiré toutes les leçons de l’histoire du Distilbène DES

Perturbateurs Endocriniens et Troubles du Comportement, Témoignages et Recherche Scientifique

Affiche de la Conférence du Docteur Marie-Odile Soyer-Gobillard sur Flickr  DES Diethylstilbestrol's photostream on Flickr

Le but d’HHORAGES-France, c’est d’établir la relation de cause à effet entre la prise d’hormones sexuelles de synthèse lors des grossesses et tous les troubles générés, à plus ou moins long terme, chez les enfants issus de ces grossesses.

Revue de Presse – Médecine & Longévité – Lisez Perturbateurs endocriniens et troubles du comportement : non, nous n’avons pas encore tiré toutes les leçons de l’histoire du DES publié par Elsevier.

Le Distilbène DES, en savoir plus

Pregnancy Exposure to High-Fat and Estrogen increases Breast Cancer Inheritance in Three Generations of Offspring

High-fat or ethinyl-oestradiol intake during pregnancy increases mammary cancer risk in several generations of offspring

Pregnancy Exposure Increases Breast Cancer Inheritance in OffspringA study by researchers from Georgetown Lombardi Comprehensive Cancer Center and Virginia Tech shows that exposure to diets high in fat or a large amount of estrogen during pregnancy can heighten the risk of breast cancer for numerous subsequent generations of female offspring, including daughters, granddaughters and great-granddaughters. ”

Abstract

Maternal exposures to environmental factors during pregnancy influence the risk of many chronic adult-onset diseases in the offspring. Here we investigate whether feeding pregnant rats a high-fat (HF)- or ethinyl-oestradiol (EE2)-supplemented diet affects carcinogen-induced mammary cancer risk in daughters, granddaughters and great-granddaughters. We show that mammary tumourigenesis is higher in daughters and granddaughters of HF rat dams and in daughters and great-granddaughters of EE2 rat dams. Outcross experiments suggest that the increase in mammary cancer risk is transmitted to HF granddaughters equally through the female or male germ lines, but it is only transmitted to EE2 granddaughters through the female germ line. The effects of maternal EE2 exposure on offspring’s mammary cancer risk are associated with changes in the DNA methylation machinery and methylation patterns in mammary tissue of all three EE2 generations. We conclude that dietary and oestrogenic exposures in pregnancy increase breast cancer risk in multiple generations of offspring, possibly through epigenetic means.

  • Read Pregnancy Exposure Increases Breast Cancer Inheritance in Offspringredorbit, September 2012..
  • High-fat or ethinyl-oestradiol intake during pregnancy increases mammary cancer risk in several generations of offspring, nature, 11 September 2012.
  • Pregnancy exposures determine risk of breast cancer in multiple generations of offspring, eurekalert, 11-SEP-2012.
  • DES studies on epigenetics and transgenerational effects.

Pharmaceutical Companies deliberately mislead Doctors into prescribing useless, harmful Meds

Doctors end up prescribing useless (or harmful) medicines

Pharmaceutical companies deliberately mislead doctors into prescribing useless and even harmful medsWriting in the Guardian, Ben Goldacre reveals the shocking truth about the drugs that doctors prescribe: thanks to aggressive manipulation from the pharmaceutical companies and passivity from regulators, doctors often don’t know that the drugs were ineffective (or harmful) in a majority of their clinical trials. ”

Read Pharmaceutical companies deliberately mislead doctors into prescribing useless and even harmful meds by Cory Doctorow, SEP 22, 2012.

Lower Survival Rates for late-stage Breast Cancer in the United Kingdom

Stage at diagnosis and breast cancer survival

More women in the UK had missing information about the stage of their cancer at diagnosis

Lower Survival Rates for late-stage Breast Cancer in the United Kingdom.

Women with late-stage breast cancer have lower survival rates in the UK than five other high-income countries, including Sweden and Canada, suggests a study in the British Journal of Cancer. ”

Natural Options to ease the Menopause Symptoms naturally !

Top tips to ease menopause symptoms naturally!

Menopause is a difficult phase in every woman’s life, but it cannot be avoided… We present to you a few natural, free-from-side-effect options

Read Top tips to ease menopause symptoms naturally!

Women’s Exposure to Chemicals may explain unexpected Breast Cancer

Age at time of exposure matters for chemicals

Women's Exposure to Chemicals may explain unexpected Breast Cancer

Vials of blood from the 1960s may help resolve why women without a family history still developed breast cancer

The FDA stance regarding… Prescription Drug side-Effects!

Fatal Drugs Allowed?

What about DES, the FDA and Eli Lilly?

What does FDA stand for? Fatal Drugs Allowed? or does “F” stand for Failure? Looking forward to read your suggestions …
Graphics by by Dave Granlund.

What about DES and the FDA?
It is Time for Actions: did you SIGN THE PETITION?

DES DiEthylStilbestrol Resources

Silent Trauma

Judith Barrow’s story is fiction, but the facts are real…

Silent Trauma by Judith Barrow on FlickrWhen Meg Matthews gives a radio interview about the devastating effects a drug has had on her life she has no idea that there will be anyone else who has suffered in a similar way. But soon she is contacted by three other women who share the same terrible secret: Rachel, a woman struggling with a failing marriage, Jackie, with a series of unsuccessful gay relationships behind her and Avril, a recluse. Each one has their own story. Each one believed that they were alone. In any other circumstances their lives would never have crossed but now they are drawn together in friendship because of the terrible consequences of a drug prescribed to pregnant women for over forty years during the middle of the twentieth century. Used ostensibly to supposedly prevent miscarriages Stilboestrol (Diethylstilbestrol DES) caused unforeseen internal damage to the unborn daughters of these women that was not discovered for years. Alone, the four women were powerless; together they are a force to be reckoned with. Determined to bring publicity to the destruction caused by the drug they hit on an unusual and innovative idea to bring it to the public’s attention.

DES Books

More DES DiEthylStilbestrol Resources

Everyday Chemicals may pose serious Health Risk

UN, WHO panel calls hormone-disrupting chemicals a global threat

Read UN, WHO panel calls hormone-disrupting chemicals a 'global threat'Rising exposure to chemicals that disrupt and mimic hormones – endocrine disruptors – may present a significant threat to human health, especially that of children in the womb, and to wildlife populations, a new global study of the effect of man-made substances in the environment has concluded. Study produced for the World Health Organisation (WHO) and the United Nations Environment Programme (UNEP).

Read UN, WHO panel calls hormone-disrupting chemicals a ‘global threat’, by Brian Bienkowski, Environmental, environmentalhealthnews, Feb. 19, 2013.

EDCs Reports