We need Safe Chemicals Act
The BRCA Gene and Family History
In her post My Medical Choice, published today in The NewYorkTimes, Angelina Jolie bravely revealed she had a preventative double mastectomy after finding out she is a carrier of the BRCA1 gene.
- Under what circumstances would a woman have a preventative double mastectomy?
- How many women undergo preventative double mastectomy in the UK?
- Is a preventative double mastectomy the only option in some circumstances?
- Talk us through the entire procedure, from start to finish
- Can you receive this treatment on the NHS? And what aftercare is available?
- Read The Huffington Post UK article, 14/05/2013
- What are the BRCA genes?
- What does it mean for those that carry a faulty gene?
- What is the likelihood of having either of these faulty genes and if you do what’s the likelihood of contracting breast cancer?
- Who is eligible to be tested for these faulty genes?
- If someone’s mother had breast cancer does that mean they have a family history?
- Read Breakthrough Breast Cancer article, 14/05/2013
India’s U.S. Drug Rulings Earn Trade Blacklist Spot From Obama Administration
The United States placed India on a special trade blacklist last week, a move some public health advocates said was retaliation for the country allowing generic versions of expensive drugs preferred by the U.S. government… The Office of the U.S. Trade Representative objected to aspects of India’s patent system in their latest report.
- Video by Micheal Newsmaker, Published on 2 May 2013
- Read India’s U.S. Drug Rulings Earn Trade Blacklist Spot From Obama Administration, HuffPostPolitics, 05/01/2013.
- Watch our DES Videos in English Playlist on
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Warnings From a Flabby Mouse
This confirms the 2005 NIEHS Study where DES appears to permanently disrupt the hormonal mechanisms regulating body weight in mice – (see Elizabeth Grossman’s “Chemicals May Play Role in Rise in Obesity“).
The common thread is that the most important time for exposure appears to be in utero and in childhood. Should doctors do more to warn pregnant women about certain chemicals?
Read Warnings From a Flabby Mouse, by Nicholas D. Kristof
The NewYorkTimes, January 2013
- Transgenerational Inheritance of Increased Fat Depot Size, Stem Cell Reprogramming, and Hepatic Steatosis Elicited by Prenatal Exposure to the Obesogen Tributyltin in Mice,
EHP, 1205701, January 2013.
- Developmental exposure to estrogenic compounds and obesity,
NIEHS Symposium Proceedings, 10.1002/bdra.20147, June 2005.
DES and Obesity
- Developmental Exposure to Endocrine Disruptors and the Obesity Epidemic – 2007
- Developmental exposure to estrogenic compounds and obesity – 2005
- Environmental Estrogens and Obesity: the Developmental Exposed DES Animal Model – 2009
- Perinatal exposure to environmental estrogens and the development of obesity – 2007
- Prenatal diethylstilbestrol exposure and risk of obesity in adult women – 2015
Personal Stories via MyFertilityChoices.com
” My name is Janice. I met my husband when I was in college and we got married right after we graduated. I assumed that we’d eventually have kids but we wanted to get our careers going and enjoy our freedom before we settled down. We worked hard and played hard and I assumed we had loads of time to eventually become parents. Then when I started to feel “ready” to have kids, our relationship started to fall apart. ”
Sadly for many DES daughters having their own children is not possible! Many of us who have experienced miscarriages, want to have kids but are struggling or unable to…
Le DES a t-il engendré des troubles psychiatriques chez les enfants exposés?
Hhorages a rassemblé le témoignage de 1240 familles dont 1734 enfants ont été exposés au DES. Parmi eux, plus de la moitié (949) sont atteints de problèmes psychiatriques seuls, 464 ont en plus des troubles somatiques et 190 des troubles somatiques seuls. Une autre étude sur 529 familles, réalisée par l’association et publiée dans le journal Médecine et Longévité en 2011, constate que sur 740 enfants ayant subi une exposition prénatale au DES, 405 ont des troubles psychiatriques.
- Troubles psy, l’autre scandale du Distilbène?
par Brigitte Bègue, Mars 2013.
- Vidéo: Le Distilbène a t-il engendré des Troubles Psychiatriques chez les Enfants exposés?
- Perturbateurs endocriniens et troubles du comportement:
non, nous n’avons pas encore tiré toutes les leçons de l’histoire du DES, publié par Elsevier.
Le Distilbène DES, en savoir plus
- Conséquences pour les petits-enfants DES, étude Distilbène trois générations.
- Effets transgénérationnels des perturbateurs endocriniens: les leçons du DES.
- Effets transgénérationnels du Distilbène, cette hormone sensée prévenir les fausses couches.
- Notre liste de vidéos DES en français sur YouTube.
- Tous nos posts tagués Distilbène.
GSK gives update on plans to share detailed clinical trial data as part of its commitment to transparency
GlaxoSmithKline (GSK) new online system will enable researchers to request access to anonymised patient level data that sit behind the results of clinical trials.
It is hoped that sharing these data with researchers will help to further scientific research, increase understanding of new and current medicines and ultimately improve patient care.
Will other pharmaceutical companies follow?
Sadly for many DES daughters this right has been stolen!
Sadly for many DES daughters this right has been stolen! For those of us who have experienced miscarriages, who want to have kids but are struggling or unable to, Mother’s Day serves as a stark reminder filled with personal sorrow … Read DES pregnancy risks to find out more.
More DES DiEthylStilbestrol Resources
- DES studies on cancers and screening.
- DES studies on epigenetics and transgenerational effects.
- DES studies on fertility and pregnancy.
- DES studies on gender identity and psychological health.
- DES studies on in-utero exposure to DES and side-effects.
- DES studies on the genital tract.
- Papers on DES lawsuits.
- DES videos and posts tagged DES, the DES-exposed, DES victims.
Relationship between urinary bisphenol A levels and prediabetes among subjects free of diabete
A new research examined 3,516 people using the National Health and Nutritional Examination Survey of 2003-2008 and compared the urinary BPA levels with fasting glucose levels to determine if there was a relationship between higher BPA concentration in the body and a prediabetic condition. It has confirmed other research finding that Bisphenol A (BPA) may lead or contribute to type 2 diabetes.
Bisphenol A (BPA) is a high volume production chemical used in the manufacture of polycarbonate plastics and epoxy resins. Recent experimental studies have suggested that BPA affects glucose metabolism through diverse mechanisms including insulin resistance, pancreatic β-cell dysfunction, adipogenesis, inflammation and oxidative stress. Prediabetes is a stage earlier in the hyperglycemia continuum associated with increased future risk of developing diabetes. Therefore, we examined the association between BPA exposure and prediabetes among subjects free of diabetes. We examined the association between urinary BPA levels and prediabetes in 3,516 subjects from the National Health and Nutritional Examination Survey 2003-2008. Urinary BPA levels were examined in tertiles. Prediabetes was defined as fasting glucose concentration 100-125 mg/dL or 2-h glucose concentration of 140-199 mg/dL or an A1C value of 5.7-6.4 %. Overall, we observed a positive association between higher levels of urinary BPA and prediabetes, independent of potential confounders including body mass index, alcohol intake, blood pressure and serum cholesterol levels. Compared to tertile 1 (referent), the multivariate-adjusted odds ratio (95 % confidence interval) of prediabetes associated with tertile 3 of BPA was 1.34 (1.03-1.73), p-trend = 0.02. In subgroup analysis, this association was stronger among women and obese subjects. Higher urinary BPA levels are found to be associated with prediabetes independent of traditional diabetes risk factors. Future prospective studies are needed to confirm or disprove this finding.
- Read Heightened BPA Exposure Linked to Diabetes
by Case Adams, Naturopath, May 11th 2013.
- Study: Relationship between urinary bisphenol A levels and prediabetes among subjects free of diabetes, NCBI, 2013 Aug.