DES, trois initiales qui ont bouleversé la vie de trois générations depuis les années 1950. Après vingt ans de combats judicaires, les victimes du distilbène ont à nouveau la parole. Pour la première fois en France, une étude épidémiologique sur les trois générations concernées est menée sur les effets de cette hormone de synthèse.
L’enquête nationale sur les conséquences du DES, commençée en avril 2013, cible notamment à évaluer le lien entre l’exposition au distilbène in-utero et le risque de développement du cancer du sein, et couvre les trois générations victimes de ce médicament.
The increased risk can be traced to prostate stem and progenitor cells
In-Utero exposure to bisphenol A (BPA) causes an increased cancer risk in an animal model of human prostate cancer, according to researcher Dr. Gail Prins, professor of physiology and director of the andrology laboratory in urology at University of Illinois at Chicago College of Medicine.
” Previous studies by Dr. Prins and colleagues using rats showed that exposure to elevated estrogen or BPA during embryonic development increased the rate of prostate cancer later in life. To determine if there was a link in humans, Dr. Prins developed a new animal model using human prostate stem cells implanted into mouse “hosts.” ”
Selective serotonin reuptake inhibitors in pregnancy and congenital malformations: population based cohort study
Children born to women taking anti-depressants in early pregnancy have a small but important increased risk of heart defects, Danish researchers say.
To investigate any association between selective serotonin reuptake inhibitors (SSRIs) taken during pregnancy and congenital major malformations.
Population based cohort study.
493 113 children born in Denmark, 1996-2003.
Main outcome measure
Major malformations categorised according to Eurocat (European Surveillance of Congenital Anomalies) with additional diagnostic grouping of heart defects. Nationwide registers on medical redemptions (filled prescriptions), delivery, and hospital diagnosis provided information on mothers and newborns. Follow-up data available to December 2005.
Redemptions for SSRIs were not associated with major malformations overall but were associated with septal heart defects (odds ratio 1.99, 95% confidence interval 1.13 to 3.53). For individual SSRIs, the odds ratio for septal heart defects was 3.25 (1.21 to 8.75) for sertraline, 2.52 (1.04 to 6.10) for citalopram, and 1.34 (0.33 to 5.41) for fluoxetine. Redemptions for more than one type of SSRI were associated with septal heart defects (4.70, 1.74 to 12.7)). The absolute increase in the prevalence of malformations was low—for example, the prevalence of septal heart defects was 0.5% (2315/493 113) among unexposed children, 0.9% (12/1370) among children whose mothers were prescribed any SSRI, and 2.1% (4/193) among children whose mothers were prescribed more than one type of SSRI.
There is an increased prevalence of septal heart defects among children whose mothers were prescribed an SSRI in early pregnancy, particularly sertraline and citalopram. The largest association was found for children of women who redeemed prescriptions for more than one type of SSRI.
Bisphenol S Disrupts Estradiol-Induced Nongenomic Signaling in a Rat Pituitary Cell Line: Effects on Cell Functions
Just like the controversial Bisphenol A that it designed to replace, Bisphenol S chemical used in cash register receipts and other consumer products messes with hormones, according to research by University of Texas scientists. The study is the first to link low concentrations of BPS – a BPA alternative – to disruption of estrogen, spurring concern that it might harm human health. Researchers exposed rat cells to levels of BPS that are within the range people are exposed to…. and, just like BPA, the compound interfered with how cells respond to natural estrogen, which is vital for reproduction and other functions.
Another good reason for women to have regular Pap smears.: ” Women with screen-detected cervical cancer had a 26% absolute increase in cure rate as compared with women who were symptomatic at diagnosis, results of a Swedish study showed. ”
To determine whether detection of invasive cervical cancer by screening results in better prognosis or merely increases the lead time until death.
Nationwide population based cohort study.
All 1230 women with cervical cancer diagnosed during 1999-2001 in Sweden prospectively followed up for an average of 8.5 years.
Main outcome measures
Cure proportions and five year relative survival ratios, stratified by screening history, mode of detection, age, histopathological type, and FIGO (International Federation of Gynecology and Obstetrics) stage.
In the screening ages, the cure proportion for women with screen detected invasive cancer was 92% (95% confidence interval 75% to 98%) and for symptomatic women was 66% (62% to 70%), a statistically significant difference in cure of 26% (16% to 36%). Among symptomatic women, the cure proportion was significantly higher for those who had been screened according to recommendations (interval cancers) than among those overdue for screening: difference in cure 14% (95% confidence interval 6% to 23%). Cure proportions were similar for all histopathological types except small cell carcinomas and were closely related to FIGO stage. A significantly higher cure proportion for screen detected cancers remained after adjustment for stage at diagnosis (difference 15%, 7% to 22%).
Screening is associated with improved cure of cervical cancer. Confounding cannot be ruled out, but the effect was not attributable to lead time bias and was larger than what is reflected by down-staging. Evaluations of screening programmes should consider the assessment of cure proportions.
If you, a loved one, or anyone you know is taking drugs recommend by a MD or Psychiatrist for Anxiety, Depression, Bi-Polar, ADHD, Obsessive Compulsive, Schizophrenia etc… then this film is an absolute must watch.
” This is the definitive documentary on the psychiatric drugging industry. Here is the real story of the high income partnership between psychiatry and drug companies that has created an $80 billion psychotropic drug profit centre. But appearances are deceiving. How valid are psychiatrists diagnoses and how safe are their drugs? Digging deep beneath the corporate veneer, this three-part documentary exposes the truth behind the slick marketing schemes and scientific deceit that conceal dangerous and often deadly sales campaign. “
Over the last decade or so, the FDA has quietly become an agent of organized scientific fraud designed to promote the profits of drug companies at the expense of public health. One of the ways this is accomplished is by rigging drug review panels with industry “experts” who maintain financial ties to pharmaceutical companies.