Restoring invisible and abandoned Trials: a call for People to publish the Findings

Unmasking ‘Invisible’ Drug Trials

Unmasking 'Invisible' Drug Trials
RIAT: Restoring Invisible and Abandoned Trials

Unpublished and misreported studies make it difficult to determine the true value of a treatment. Peter Doshi and colleagues call for sponsors and investigators of abandoned studies to publish (or republish) and propose a system for independent publishing if sponsors fail to respond.

  • A call to publish—or be published
  • A call to action, publishing trials, credibly
  • Call for restorative authors and participating journals

Read Unmasking ‘Invisible’ Drug Trials
by Jennifer Couzin-Frankel, ScienceInsider, 13 June 2013

Sources: Restoring invisible and abandoned trials: a call for people to publish the findings, by Peter Doshi, 13 June 2013

Women’s Symptoms of Cancer, Heart Disease, Liver Problems different to Men’s

When it comes to illness, men and women really do react differently

Women's symptoms of cancer, heart disease and liver problems are significantly different to men's, experts warn
When it comes to illness, men and women really do react differently, Italian researchers have found

Medical research conducted over the past 40 years has focused almost exclusively on male patients, say Italian researchers… Women suffering cardiac arrest suffer abdominal pain and nausea, NOT the standard warning signs of chest pain radiating down left arm… Women’s non-specific symptoms mean inadequate treatment is given… ”

Read Women’s symptoms of cancer, heart disease and liver problems are significantly different to men’s, experts warn
by Nicola Rowe, UK DailyMail Online

Bisphenol-A chemical found in canned Foods and Plastics may increase your Heart Disease Risk

Does BPA exposure cause heart disease?

Bisphenol-A #BPA chemical found in canned Foods and Plastics, may increase your Heart Disease Risk
Does BPA exposure cause heart disease?

As one of the world’s highest production volume chemicals, Bisphenol-A is incredibly common in food and drinks packaging, as well as in other places you probably wouldn’t expect, like receipts.
A study in Analytical and Bioanalytical Chemistry found that of 13 thermal printing papers (the type often used for receipts) analyzed, 11 contained BPA.v Holding the paper for just 5 seconds was enough to transfer BPA onto a person’s skin, and the amount of BPA transferred increased by about 10 times if the fingers were wet or greasy.

Read Eating Canned Food Shown to be Linked to Heart Disease

  • Does BPA Exposure Cause Heart Disease?
  • BPA Also Linked to Obesity, Insulin Resistance, Reproductive Problems …
  • Plastics are NOT the Only Route of Exposure to BPA …
  • Is it Possible to Avoid Having Your Health Damaged by BPA?

by Dr. Mercola, March 15, 2012
Many thanks to Ruth for this key find and comment 🙂

” Life becomes easier when you learn to accept an Apology you never got “

~Robert Brault~ #Quote

Diethylstilbestrol, Journal of a DES Daughter on Facebook
The FDA didn’t ban DES and today recognizes the DES tragedy but refuses to apologize to the victims.
Pharmaceutical giant Eli Lilly who manufactured DES in the US has never accepted responsibility nor apologized for the DES tragedy.
Should DES victims learn to accept an apology they will never get? …
Nine people commented so far, what do you think?

Related posts:

Collective Redress In Europe – Litigation, Mediation and Arbitration

As national class actions duel in Canada, there is no better time to look to Europe

European Union: Brave New Old World - Collective Redress In Europe - Part 1
DES is cited as an example for collective settlements in The Netherlands

Quite technical but very interesting article which helps understand some of the EU legislation that authorizes collective actions. DES is cited as an example for collective settlements in The Netherlands.

Read European Union: Brave New Old World – Collective Redress In Europe – Part 1, by Louise Moher, January 9 2012

  • The Diverse Approaches to Collective Redress in Europe
  • Seeking Guidance from the European Union on Multi-Jurisdictional Issues
  • Proposals and Debate Regarding European Union Harmonizing Legislation
  • The Jurisdictional Competence of the European Union to Enact Harmonizing Legislation
  • Europe’s Multi-Jurisdictional Nightmare Explained
  • The Royal Dutch/Shell Settlement May Be a Turning Point

Read papers on DES lawsuits.

Breast Cancer Screening may not have reduced Deaths from the Disease

You’re the doctor. You decide. What would you do?

Breast cancer screening: ‘You’re the doctor, what would you do?’

” A new study from Oxford University suggests that breast cancer screening may not have reduced deaths from the disease – decisions about treatment aren’t always clear-cut . “

Read Breast cancer screening:
You’re the doctor, what would you do?’

By Theodore Dalrymple, The Telegraph, 11 Jun 2013

Related post: The NHS shares its Views on the Findings of a New Study on the Value of Breast Cancer Screening, 14 Jun 2013

Is the FDA about to greenlight a Drug banned in other Countries?

Tell the FDA to Reject the Panel’s Advice on Avandia!

Is FDA About to Greenlight a Drug Banned in Other Countries?
Tell the FDA to reject the Panel’s Advice on Avandia!

At the time it was withdrawn, Avandia was the best-selling diabetes pill in the world, and an estimated 90,000 people were taking it in the UK … It was banned by European regulators in 2010.

Read Is FDA About to Greenlight a Drug Banned in Other Countries?
by Alliance for Natural Health USA, June 11, 2013

How to Tell the FDA to Reject the Panel’s Advice on Avandia!

DES mentioned as a Warning in new ACOG President’s inaugural Speech!

Jeanne Conry, MD, PhD, sworn in as ACOG’s 64th president

Jeanne Conry, MD, PhD, sworn in as ACOG’s 64th president
DES mentioned as a Warning

DES Action USA recently commented: ” We always say the DES story must be told so it doesn’t happen again. The new president of the American College of Obstetricians and Gynecologists agrees – and specifically mentioned DES in her inaugural speech. Progress!!!!

Read Jeanne Conry, MD, PhD, sworn in as ACOG’s 64th president
The American College of Obstetricians and Gynecologists.

More DES DiEthylStilbestrol Resources

Facebook’s new Policy allowing Mastectomy Photos

Stop censoring photos of men and women who have undergone mastectomies

Stop censoring photos of men and women who have undergone mastectomies
Facebook’s new policy allowing Mastectomy Photos

Congratulations on the victory of the petition asking Facebook to stop censoring photos of men and women who have undergone mastectomies! “We want the world to know breast cancer is not a pink ribbon – it is traumatic, it is life-changing, and it urgently needs a cure.” says Scorchy Barrington who launched the petition signed by more than 21,000 people.

Read/Join : Stop censoring photos of men and women who have undergone mastectomies – Read Facebook newly published policy

Visit The SCAR Project website – Facebook Page

BPA linked to Obesity Risk and Overweight in Puberty-Age Girls

Endocrine Disruptors permanent effect on Obesity through at least three Generations

BPA Linked to Obesity Risk in Puberty-Age Girls
Urine Bisphenol-A Level in Relation to Obesity and Overweight in School-Age Children

Girls between 9 and 12 years of age with higher-than-average levels of bisphenol-A (BPA) in their urine had double the risk of being obese than girls with lower levels of BPA, according to a Kaiser Permanente study published today …
Read moreScienceDaily, June 12, 2013.

BPA is an estrogen-like endocrine-disrupting chemical very similar to DES. Read one of our previous blog post: “Endocrine Disruptors permanent effect on Obesity through at least three Generations“.

2013 Study Abstract

Bisphenol-A (BPA) is a potential endocrine disruptor impacting metabolic processes and increasing the risk of obesity. To determine whether urine BPA level is associated with overweight/obesity in school-age children, we examined 1,326 students in grades 4–12 from three schools (one elementary, one middle, and one high school) in Shanghai. More than 98% of eligible students participated. Total urine BPA concentration was measured and anthropometric measures were taken by trained research staff. Information on risk factors for childhood obesity was collected for potential confounders. Age- and gender-specific weight greater than 90th percentile of the underlying population was the outcome measure. After adjustment for potential confounders, a higher urine BPA level (≥2 µg/L), at the level corresponding to the median urine BPA level in the U.S. population, was associated with more than two-fold increased risk of having weight >90th percentile among girls aged 9–12 (adjusted odds ratio (aOR) = 2.32, 95% confidence interval: 1.15–4.65). The association showed a dose-response relationship with increasing urine BPA level associated with further increased risk of overweight (p = 0.006 for trend test). Other anthropometric measures of obesity showed similar results. The same association was not observed among boys. This gender difference of BPA effect was consistent with findings from experimental studies and previous epidemiological studies. Our study suggests that BPA could be a potential new environmental obesogen. Widespread exposure to BPA in the human population may also be contributing to the worldwide obesity epidemic.

Sources: PlosOne, June 12, 2013.