Milk does a Body good? Sometimes, not always…

No matter what dairy product you’re choosing, stick with low-fat, but also no sugar

Milk does a body good? Maybe not always, Harvard doc argues
Milk can be a significant source of additional sugar and calories

A Harvard pediatrician is arguing that the current U.S. recommendation of three servings of dairy a day isn’t necessarily one-size-fits-all. For some, it may be a significant source of additional sugar and calories.

Read Milk does a body good? Maybe not always, Harvard doc argues, by Melissa Dahl,
Today Health, 1 July 2013.

Related posts:

Adenocarcinoma of the Vagina: Maternal Stilbestrol ingestion leading to future Cancer in Offspring

Association of Maternal Stilbestrol Therapy with Tumor Appearance in Young DES Daughters

1971 Study Abstract

image of Diethylstilbestrol DES clear cell adenocarcinoma CCA vaginal cancer
Diethylstilbestrol clear cell adenocarcinoma vaginal cancer

Adenocarcinoma of the vagina in young women had been recorded rarely before the report of several cases treated at the Vincent Memorial Hospital between 1966 and 1969. The unusual occurrence of this tumor in eight patients born in New England hospitals between 1946 and 1951 led us to conduct a retrospective investigation in search of factors that might be associated with tumor appearance. Four matched controls were established for each patient; data were obtained by personal interview. Results show maternal bleeding during the current pregnancy and previous pregnancy loss were more common in the study group. Most significantly, seven of the eight mothers of patients with carcinoma had been treated with diethylstilbestrol started during the first trimester. None in the control group were so treated (p less than 0.00001). Maternal ingestion of stilbestrol during early pregnancy appears to have enhanced the risk of vaginal adenocarcinoma developing years later in the offspring exposed.

Sources

Adenocarcinoma of the Vagina — Association of Maternal Stilbestrol Therapy with Tumor Appearance in Young Women, Arthur L. Herbst, M.D., Howard Ulfelder, M.D., and David C. Poskanzer, M.D., N Engl J Med 1971. Full article NEJM197104222841604 and PDF.

More DES DiEthylStilbestrol Resources

BPA, Endocrine Disruptors, Phthalates : Evolution or Extinction of Men?

Manly Man to Metrosexual Man to Extinction?!

Evolution or Extinction of Men?
Evolution or Extinction of Men?

Interesting article!

  • Are the dangerous endocrine disruptors affecting men?
  • If so, when does it start?
  • What does it do?
  • How can we protect our men?

Read Evolution or Extinction of Men, Hormones Matter, May 2012.

More information

LandMark Trial when Judge Finz argued that without Lilly DES copycats Drugs would not have existed

Finz considers his landmark case to be a successful 1979 lawsuit against Eli Lily & Co

Mystery author’s life a page-turner
Finz said he considers his landmark case to be a successful 1979 lawsuit against the pharmaceutical manufacturer Eli Lily and Company.

Soldier, entertainer, state Supreme Court justice and novelist, Leonard Finz talks about his life including the 1979 DES lawsuit against the pharmaceutical manufacturer Eli Lilly “It opened the gates of justice for other victims to go ahead with their own proceedings,” Finz said.

Read Mystery author’s life a page-turner
TheIslandNow, June 27, 2013.

More DES DiEthylStilbestrol Resources

Quand la “bulle médicale” va-t-elle éclater?

La situation de la médecine est très proche de celle de l’économie des années 2000

Quand la
par Dominique Dupagne, janvier 2009

” … En revanche, dans l’affaire du Distilbène, des millions de femmes ont été touchées dans le monde alors que l’on savait dès 1945 que ce produit n’avait aucun intérêt pour traiter les menaces d’accouchement prématuré. La poursuite de la prescription du Distilbène aux femmes enceintes jusqu’en 1971 est inexcusable… ”

Lisez Quand la “bulle médicale” va-t-elle éclater?
de Dominique Dupagne,  26 janvier 2009.

Le Distilbène DES, en savoir plus

Taking AntiDepressants in early Pregnancy is not worth taking

Antidepressants could be risk to unborn babies

Antidepressants 'could be risk to unborn babies'
Do you think those extra risks are really worth taking?

The risk posed by some popular antidepressants in early pregnancy is not worth taking for women with mild to moderate depression, an expert has warned. Professor Stephen Pilling says evidence suggests SSRIs can double the risk of a child being born with a heart defect.

Read Antidepressants ‘could be risk to unborn babies’
BBC News, 24 June 2013

Related posts:

Sadly for many DES daughters having their own children is not possible! Many of us who have experienced miscarriages, want to have kids but are struggling or unable to…

IVF for Male Infertility linked to increased Risk of Intellectual Disability and Autism in Children

Autism and Mental Retardation Among Offspring Born After In Vitro Fertilization

IVF for Male Infertility linked to increased Risk of Intellectual Disability and Autism in ChildrenIn the first study to compare all available IVF treatments and the risk of neurodevelopmental disorders in children, researchers find that IVF treatments for the most severe forms of male infertility are associated with an increased risk of intellectual disability and autism in children.

Abstract

Importance
Between 1978 and 2010, approximately 5 million infants were born after in vitro fertilization (IVF) treatments. Yet limited information on neurodevelopment after IVF exists, especially after the first year of life.

Objective
To examine the association between use of any IVF and different IVF procedures and the risk of autistic disorder and mental retardation in the offspring.

Design, Setting, and Participants
A population-based, prospective cohort study using Swedish national health registers. Offspring born between 1982 and 2007 were followed up for a clinical diagnosis of autistic disorder or mental retardation until December 31, 2009. The exposure of interest was IVF, categorized according to whether intracytoplasmic sperm injection (ICSI) for male infertility was used and whether embryos were fresh or frozen. For ICSI, whether sperm were ejaculated or surgically extracted was also considered.

Main Outcomes and Measures
Relative risks (RRs) for autistic disorder and mental retardation and rates per 100 000 person-years, comparing spontaneously conceived offspring with those born after an IVF procedure and comparing 5 IVF procedures used in Sweden vs IVF without ICSI with fresh embryo transfer, the most common treatment. We also analyzed the subgroup restricted to singletons.

Results
Of the more than 2.5 million infants born, 30 959 (1.2%) were conceived by IVF and were followed up for a mean 10 (SD, 6) years. Overall, 103 of 6959 children (1.5%) with autistic disorder and 180 of 15 830 (1.1%) with mental retardation were conceived by IVF. The RR for autistic disorder after any procedure compared with spontaneous conception was 1.14 (95% CI, 0.94-1.39; 19.0 vs 15.6 per 100 000 person-years). The RR for mental retardation was 1.18 (95% CI, 1.01-1.36; 46.3 vs 39.8 per 100 000 person-years). For both outcomes, there was no statistically significant association when restricting analysis to singletons. Compared with IVF without ICSI with fresh embryo transfer, there were statistically significantly increased risks of autistic disorder following ICSI using surgically extracted sperm and fresh embryos (RR, 4.60 [95% CI, 2.14-9.88]; 135.7 vs 29.3 per 100 000 person-years); for mental retardation following ICSI using surgically extracted sperm and fresh embryos (RR, 2.35 [95% CI, 1.01-5.45]; 144.1 vs 60.8 per 100 000 person-years); and following ICSI using ejaculated sperm and fresh embryos (RR, 1.47 [95% CI, 1.03-2.09]; 90.6 vs 60.8 per 100 000 person-years). When restricting the analysis to singletons, the risks of autistic disorder associated with ICSI using surgically extracted sperm were not statistically significant, but the risks associated with ICSI using frozen embryos were significant for mental retardation (with frozen embryos, RR, 2.36 [95% CI, 1.04-5.36], 118.4 vs 50.6 per 100 000 person-years]; with fresh embryos, RR, 1.60 [95% CI, 1.00-2.57], 80.0 vs 50.6 per 100 000 person-years).

Conclusions and Relevance
Compared with spontaneous conception, IVF treatment overall was not associated with autistic disorder but was associated with a small but statistically significantly increased risk of mental retardation. For specific procedures, IVF with ICSI for paternal infertility was associated with a small increase in the RR for autistic disorder and mental retardation compared with IVF without ICSI. The prevalence of these disorders was low, and the increase in absolute risk associated with IVF was small.

Between 1978 and 2012, approximately 5 million infants worldwide were born from in vitro fertilization (IVF). The original IVF procedure, allowing an egg to be fertilized by sperm in vitro, is usually used in the absence of male-factor infertility. This procedure is used in Sweden in about half of all treatments. Embryos can be transferred immediately after fertilization (fresh) or frozen for later use. The introduction of intracytoplasmic sperm injection (ICSI) in 1992,1 in which a sperm is injected into an egg, allows treatment for male-factor infertility. For ICSI, sperm can be collected by ejaculation or surgical extraction.

Studies have demonstrated that IVF with or without ICSI is generally safe2 but can be associated with an increased risk for perinatal complications, including preterm birth.3 Concern has been raised about ICSI in particular,4 which bypasses the natural selection of sperm, may physically damage the egg, and may contaminate the cytoplasm of the egg cell with culture media when the sperm is inserted. In vitro fertilization procedures have also been associated with several neurological disorders, including cerebral palsy5 and the Russell-Silver,6 Beckwith-Wiedemann, and Angelman syndromes.6,7 No study has investigated the association between different IVF procedures and neurodevelopment, and few studies have investigated whether IVF treatments are associated with neurodevelopment after the first year of life.8 Few studies have looked at autistic disorder and mental retardation, 2 of the most severe chronic developmental disorders, affecting 1% to 3% of all children in developed countries.9(pp362-389)

This prospective cohort study was designed to analyze the hypotheses that the use of any IVF procedure as well as specific procedures are associated with an increased risk of autistic disorder and mental retardation in the offspring.

KwaliteitsCriteria: DES-dochters en Vrouwen met ClearCellAdenoCarcinoom

KwaliteitsCriteria bij Screenings-Protocol van DES-dochters

Kwaliteitscriteria DES-dochters en CCAC
Hier kunt u @DESCentrum tekst lezen, downloaden en eventueel printen

DES Centrum: ” Het jaar 2012 heeft niet alleen in het teken gestaan van verhuizing en reorganiseren. We hebben ons ook gericht op twee projecten. Het doel van beide projecten is te komen tot optimale medische zorg voor DES-dochters. ”

Lezen Kwaliteitscriteria DES-dochters en CCAC.

Kwaliteitscriteria vanuit het perspectief van vrouwen met een vorm van gynaecologische kanker
(volle tekst om te lezen, downloaden, printen).

More DES DiEthylStilbestrol Resources

Breast Cancer Risk 50% increase for Women working long-Term Night Shifts

Long-term night shift work in a diverse mix of occupations is associated with increased breast cancer risk and not limited to nurses

Breast Cancer Risk Could Double For Women Working Night Shifts
The Canadian study adds to similar results from previous research

Nurses, cleaners, care workers, some shop workers, call-centre handlers and others who work night shifts for a long time can have a twice as high risk of developing the disease than those who don’t, the new study found…
Canadian researchers examined 1,134 women with breast cancer and 1,179 women without the disease, but of the same age, and concluded that long-term night shift work in a diverse mix of occupations is associated with increased breast cancer risk and not limited to nurses, as in most previous studies.

Read Breast Cancer Risk Could Double For Women Working Night Shifts, HuffPost LyfeStyle, 2 July 2013.

Sources: Increased risk of breast cancer associated with long-term shift work in Canada, BMJ, 1 July 2013.

Finding Hope after Miscarriage…

A pregnancy loss is happening to 25% of all known pregnancies

Finding Hope After Miscarriage
Personal Stories

One year I was pregnant four times.
I was 38 and newly married. I got pregnant the first time in January.
A few weeks later, I miscarried. For every season of that year, I have a photo of me holding a pregnancy test with two pink lines marking positive. By summer my smile is tentative. Each pregnancy followed its own, idiosyncratic course. One ended gently, just days after a home test turned positive. Another hung on 10 weeks, the embryo’s heart stopping after we’d seen it pulsing during two previous ultrasounds. Another pregnancy my doctor tried to save by prescribing progesterone.
That only caused the little bundle of cells to cling to me too tenaciously, long after it stopped growing
…. ”

Continue reading Finding Hope After Miscarriage
by Kendra Hurley, Jan 10, 2013

Sadly for many DES daughters having their own children is not possible! Many of us who have experienced miscarriages, want to have kids but are struggling or unable to…