We write a lot about endocrine disruptors here at Hormones Matter™ and for whatever strange twist of fate, we seem to cover a lot of research on penis size. Believe it or not, the two are related. Endocrine disruptors are largely estrogenic in nature and when exposure occurs during certain developmental time periods, those estrogens affect penis size, form and function.
The research, led by British scientists, has also shown for the first time that the technique increased the number of babies born as a result.
Gently scratching the lining of the womb in the month before IVF treatment was shown to increase in the clinical pregnancy rate of women undergoing IVF to 49 per cent, compared with the current average of 29 per cent.
This controversial book by Joanna Moncrieff overturns the claim that psychiatric drugs work by correcting chemical imbalance, and analyzes the professional, commercial and political vested interests that have shaped this view. It provides a comprehensive critique of research on drugs including antidepressants, antipsychotics and mood stabilizers.
The physical and psychological impact of the problems associated with DES exposure are well documented
1993 Study Abstract
Accumulating evidence in experimental animals over the past three decades suggests that mammalian brain development and differentiation of the central nervous system are influenced by perinatal exposure to sex hormones. Hence, changes in human behavioral patterns may be associated with prenatal exposure to estrogenic substances such as diethylstilbestrol (DES). This paper reviews relevant studies from a series of laboratories and finds that no clear-cut differences can be demonstrated to date between unexposed and DES-exposed women in gender-related behavior, although the physical and psychological impact of the problems associated with exposure to DES are well documented. If both prenatal and postnatal influences such as social, economic, and environmental factors are taken into consideration, individual variation is more apparent than differences in gender-related behavior between unexposed and DES-exposed women. In summary, gender-related behavior is determined by a complex array of interacting factors, and prenatal influences are only one of many developmental events. More studies are needed using larger populations with carefully controlled selection criteria to suggest a direct role of prenatal DES exposure on subsequent gender-related behavior.
Researchers found that women who considered themselves “very active” had a 25 percent lower risk for breast cancer, and that postmenopausal women who walked for at least seven hours a week had a 14 percent lower risk for breast cancer.
Clinical trial registration, reporting, publication and FDAAA compliance: unacceptably low
In an effort to understand how results of human clinical trials are made public, researchers analyzed 8907 clinical trials completed in 2006-2009 and registered at ClinicalTrials.gov, the world’s largest clinical trial registry.
Only 47% of trials analyzed in their large sample provided linked publications or basic results. Despite availability of several information channels, trial record managers do not sufficiently meet the mandate to inform the public about results of clinical trials either via a linked result publication or basic results submission, although there is a temporal trend showing an increasing rate of submission of basic results.
Less Blood Clot Risk Linked to Estradiol Than to Premarin Pills
Women can choose among several types of estrogen pills, which are equally effective at relieving menopausal symptoms. In a head-to-head comparison of two major forms of hormone replacement therapy, a more natural version of estrogen proved less dangerous to the heart than a synthetic one – a patented drug marketed as Premarin.
Patti Neighmond reports, NPR newsmagazines All Things Considered
Award-winning journalist Patti Neighmond is NPR’s health policy correspondent. Her reports air regularly on NPR newsmagazines All Things Considered, Morning Edition and Weekend Edition.
Patti reported about DES on August 08, 2006, following a “new” study showing that daughters of women who took the anti-miscarriage drug DES, a synthetic estrogen, have a higher risk of developing breast cancer after age 50.
Click here to listen to All Things Considered radio show.
Maternal fruit and vegetable consumption may be protective
A new study looked specifically at a baby’s prenatal exposure to some chemicals released by materials combustion (car fumes, tobacco, grilled foods).
The researchers found that for pregnant women, the advantages of eating more fruits and vegetables go beyond the extra vitamins and minerals gained; it helps them to protect their unborn children from chemical exposure…
All physicians being monitored were diagnosed with substance dependence
Substance-related impairment of physicians is a small but serious problem, with significant consequences for patient safety and public health. The purpose of this study was to identify reasons for prescription drug misuse among physicians referred to a physician health program for monitoring because of substance-related impairment, to develop better mechanisms for prevention and intervention.
A total of 55 physicians (94.5% male) who were being monitored by their State physician health program because of substance-related impairment participated in guided focus group discussions. Participation was anonymous. Discussions were transcribed from 9 separate focus groups, lasting 60 to 90 minutes each. Qualitative analyses were conducted to examine themes.
All participants were diagnosed with substance dependence, and 69.1% of them endorsed a history of misusing prescription drugs. Participants documented the following 5 primary reasons for prescription drug misuse:
to manage physical pain,
to manage emotional/psychiatric distress,
to manage stressful situations,
to serve recreational purposes,
to avoid withdrawal symptoms.
Our results emphasize the importance of self-medication as a leading reason for misusing prescription medications, although recreational use was also an important factor. Prevention efforts targeting prescription drug misuse among physicians should be initiated during medical training, with continuing education requirements throughout the physicians’ careers.