Endocrine Disruptors stunt Penile and Testicular Development

Evolution or Extinction of Men?

Hormone research matters is @LucineWoman on Twitter

We write a lot about endocrine disruptors here at Hormones Matter™ and for whatever strange twist of fate, we seem to cover a lot of research on penis size. Believe it or not, the two are related. Endocrine disruptors are largely estrogenic in nature and when exposure occurs during certain developmental time periods, those estrogens affect penis size, form and function.



A simple 15 min Procedure costing less than 100£ nearly doubling the Success Rate of IVF Treatment

Scientists find simple ‘scratch’ technique improves IVF treatment success

Scientists find simple 'scratch' technique improves IVF treatment success
One way that egg cells may be fertilized with sperm cells in an IVF lab

The research, led by British scientists, has also shown for the first time that the technique increased the number of babies born as a result.
Gently scratching the lining of the womb in the month before IVF treatment was shown to increase in the clinical pregnancy rate of women undergoing IVF to 49 per cent, compared with the current average of 29 per cent.

Continue reading Scientists find simple ‘scratch’ technique improves IVF treatment success, by Laura Donnelly, Health Correspondent
The Telegraph, 6 Oct 2013

Related post: IVF technique increases pregnancy rates by 20%, study shows, MedicalNewsToday, 8 Oct 2013

The Myth of the Chemical Cure

A Critique of Psychiatric Drug Treatment

The Myth of the Chemical Cure
Stuart Sorensen is director of AMJ Socialcare Training and Consultancy

This controversial book by Joanna Moncrieff overturns the claim that psychiatric drugs work by correcting chemical imbalance, and analyzes the professional, commercial and political vested interests that have shaped this view. It provides a comprehensive critique of research on drugs including antidepressants, antipsychotics and mood stabilizers.

Related posts:

Gender-related Behavior in Women exposed prenatally to DiEthylStilbestrol

The physical and psychological impact of the problems associated with DES exposure are well documented

1993 Study Abstract

Gender-related behavior in women exposed prenatally to diethylstilbestrol
The physical and psychological impact of the problems associated with exposure to DES are well documented

Accumulating evidence in experimental animals over the past three decades suggests that mammalian brain development and differentiation of the central nervous system are influenced by perinatal exposure to sex hormones. Hence, changes in human behavioral patterns may be associated with prenatal exposure to estrogenic substances such as diethylstilbestrol (DES). This paper reviews relevant studies from a series of laboratories and finds that no clear-cut differences can be demonstrated to date between unexposed and DES-exposed women in gender-related behavior, although the physical and psychological impact of the problems associated with exposure to DES are well documented. If both prenatal and postnatal influences such as social, economic, and environmental factors are taken into consideration, individual variation is more apparent than differences in gender-related behavior between unexposed and DES-exposed women. In summary, gender-related behavior is determined by a complex array of interacting factors, and prenatal influences are only one of many developmental events. More studies are needed using larger populations with carefully controlled selection criteria to suggest a direct role of prenatal DES exposure on subsequent gender-related behavior.

Sources: Gender-related Behavior in Women exposed prenatally to DiEthylStilbestrol
Dr R Hoover, NCBI, Aug 1993 – full study PDF

More DES DiEthylStilbestrol Resources

Significantly lower your Risk for Breast Cancer with only a few Hours of walking per Week

Recreational Physical Activity and Leisure-Time Sitting in Relation to Postmenopausal Breast Cancer Risk

Study links moderate activity to lower breast cancer risk
Women don’t need to exercise to extremes to significantly improve their health

A new study from the American Cancer Society has found that walking may help to prevent breast cancer.

Researchers found that women who considered themselves “very active” had a 25 percent lower risk for breast cancer, and that postmenopausal women who walked for at least seven hours a week had a 14 percent lower risk for breast cancer.

DES and Breast Cancer:

Clinical Trials: Half of all Trials are missing Results in 2013

Clinical trial registration, reporting, publication and FDAAA compliance: unacceptably low

Linking ClinicalTrials.gov and PubMed to Track Results of Interventional Human Clinical Trials
PLOS ONE is an international, peer-reviewed, open-access, online publication

In an effort to understand how results of human clinical trials are made public, researchers analyzed 8907 clinical trials completed in 2006-2009 and registered at ClinicalTrials.gov, the world’s largest clinical trial registry.

Only 47% of trials analyzed in their large sample provided linked publications or basic results. Despite availability of several information channels, trial record managers do not sufficiently meet the mandate to inform the public about results of clinical trials either via a linked result publication or basic results submission, although there is a temporal trend showing an increasing rate of submission of basic results.

Read Linking ClinicalTrials.gov and PubMed to Track Results of Interventional Human Clinical Trials, PlosOne, Oct 2013

Related Posts:

Hormone Replacement Therapy: natural Form of Hormone much better than Synthetic Estrogen

Less Blood Clot Risk Linked to Estradiol Than to Premarin Pills

Less Blood Clot Risk Linked to Estradiol Than to Premarin Pills
Higher risk of incident venous thrombosis and possibly myocardial infarction with the Premarin drug

Women can choose among several types of estrogen pills, which are equally effective at relieving menopausal symptoms. In a head-to-head comparison of two major forms of hormone replacement therapy, a more natural version of estrogen proved less dangerous to the heart than a synthetic one – a patented drug marketed as Premarin.

Read Less Blood Clot Risk Linked to Estradiol Than to Premarin Pills, Science News, 30 Sept 2013.

Read Synthetic Estrogens Pose Greater Clot Risk Than Natural Forms of Hormone, by Alexandra Sifferlin, 1 Oct 2013.

Sources: Lower Risk of Cardiovascular Events in Postmenopausal Women Taking Oral Estradiol Compared With Oral Conjugated Equine Estrogens, JAMA, 30 Sept 2013.

More about estrogens and hormone replacement therapy.

DES Daughters and their Cancer Risk

Patti Neighmond reports, NPR newsmagazines All Things Considered

DES Daughters and their Cancer Risk
Patti Neighmond, Correspondent, Health Policy, Science Desk

Award-winning journalist Patti Neighmond is NPR’s health policy correspondent. Her reports air regularly on NPR newsmagazines All Things Considered, Morning Edition and Weekend Edition.

Patti reported about DES on August 08, 2006, following a “new” study showing that daughters of women who took the anti-miscarriage drug DES, a synthetic estrogen, have a higher risk of developing breast cancer after age 50.

Click here to listen to All Things Considered radio show.

Click here to read the story.

DES and Breast Cancer

More DES DiEthylStilbestrol Resources

Prenatal Protection: Maternal Diet may lower Impact of some Chemicals

Maternal fruit and vegetable consumption may be protective

Prenatal Protection: Maternal Diet May Modify Impact of PAHs
Fruit and vegetable intake during pregnancy may protect the fetus from some chemicals

A new study looked specifically at a baby’s prenatal exposure to some chemicals released by materials combustion (car fumes, tobacco, grilled foods).

The researchers found that for pregnant women, the advantages of eating more fruits and vegetables go beyond the extra vitamins and minerals gained; it helps them to protect their unborn children from chemical exposure…

Read Prenatal Protection: Maternal Diet May Modify Impact of PAHs, Environmental Health Perspectives, 03 Oct 2013

Five primary Reasons why some Doctors abuse Prescription Drugs in self-Medication

All physicians being monitored were diagnosed with substance dependence


Reasons for Misuse of Prescription Medication Among Physicians Undergoing Monitoring by a Physician Health Program
Why do doctors abuse prescription drugs? ‘Self-medication’ is key reason

Substance-related impairment of physicians is a small but serious problem, with significant consequences for patient safety and public health. The purpose of this study was to identify reasons for prescription drug misuse among physicians referred to a physician health program for monitoring because of substance-related impairment, to develop better mechanisms for prevention and intervention.

A total of 55 physicians (94.5% male) who were being monitored by their State physician health program because of substance-related impairment participated in guided focus group discussions. Participation was anonymous. Discussions were transcribed from 9 separate focus groups, lasting 60 to 90 minutes each. Qualitative analyses were conducted to examine themes.

All participants were diagnosed with substance dependence, and 69.1% of them endorsed a history of misusing prescription drugs. Participants documented the following 5 primary reasons for prescription drug misuse:

  1. to manage physical pain,
  2. to manage emotional/psychiatric distress,
  3. to manage stressful situations,
  4. to serve recreational purposes,
  5. to avoid withdrawal symptoms.

Our results emphasize the importance of self-medication as a leading reason for misusing prescription medications, although recreational use was also an important factor. Prevention efforts targeting prescription drug misuse among physicians should be initiated during medical training, with continuing education requirements throughout the physicians’ careers.

Sources: Reasons for Misuse of Prescription Medication Among Physicians Undergoing Monitoring by a Physician Health Program, Journal of Addiction Medicine, September/October 2013 – Volume 7 – Issue 5.

Read ‘Self-Medication’: Why Doctors Abuse Prescription Drugs, ScienceDaily, 4 Oct 2013.

Read Why Do Doctors Abuse Prescription Drugs? ‘Self-Medication’ Is Key Reason, Lippincott Williams & Wilkins, 4 Oct 2013.