Does it work ? Beware of the too-simple answer

Hilda Bastian is cartoonist and writer at StatisticallyFunny blog

Does it work ? Beware of the too-simple Answer...
Beware of the too-simple Answer… by @HildaBast

Beware of the too-simple answer…

Hilda Bastian is Editor etc at PubMed Health, blogger at Scientific American. Commenting on epidemiology with cartoons at Statistically Funny

Leonard is so lucky! He’s just asked a very complicated question and he’s not getting an over-confident and misleading answer. Granted, he was likely hoping for an easier one! But let’s dive into it. ”

Continue reading Does it work? Beware of the too-simple answer
by Hilda Bastian

See more Comics – about Doctors – Prescriptions Drugs – the FDA – the Pharmaceutical Industry

Related:
While heavily marketed, the DES Drugs never worked, more the opposite… like EDCs, they increase the risk of cancer and have transgenerational effects…

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Watch the Diaporama, and the Art photo set on  DES Diethylstilbestrol's photostream on Flickr

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Email your photos to des.daughter@gmail.com with a short description and title :-)

The FDA could set Personal Genetics Rights back Decades

” The FDA Is Poised to Kill the Personal Genetics Testing Industry. Its letter to 23andMe is foolish and paternalistic “

The FDA Is Poised to Kill the Personal Genetics Testing Industry
The FDA could set Personal Genetics Rights back Decades

The Food and Drug Administration’s recent directive to the company 23andMe to stop marketing its genetic tests directly to consumers is a shortsighted, heavy-handed, double-standard act of paternalism. This is the last shoe to drop in the FDA’s effort to wipe out the right of consumers to discover their own genetic information, some of the most important, private, useful, and interesting information about our own health and well-being. We should have a right to access that data about ourselves, but the practical impact of the FDA’s action will be to put most of that data out of reach for the foreseeable future. ”

Continue reading The FDA Is Poised to Kill the Personal Genetics Testing Industry, by Gary Marchant, 21 Nov 2013.

Fetal DES Exposure associated with Cryptorchidism, Testicular Hypoplasia, Semen Abnormalities

Association of diethylstilbestrol exposure in utero with cryptorchidism, testicular hypoplasia and semen abnormalities

Abstract:

Association of diethylstilbestrol exposure in utero with cryptorchidism, testicular hypoplasia and semen abnormalities
In utero exposure to Diethylstilbestrol is associated with terrible side-effects in DES Sons.
  • Epididymal cysts and/or hypoplastic testes have been found in 31.5 per cent of 308 men exposed to diethylstilbestrol in utero, compared to 7.8 per cent of 307 placebo-exposed controls.
  • Analyses of the spermatozoa have revealed severe pathological changes (Eliasson score greater than 10) in 134 diethylstilbestrol-exposed men (18 per cent) and 87 placebo-exposed men (8 per cent).
  • Further investigation of the 26 diethylstilbestrol-exposed men with testicular hypoplasia has revealed that 65 per cent had a history of cryptorchidism. Only 1 of the 6 placebo-exposed controls with testicular hypoplasia had a history of testicular maldescent.
  • Although none of our Diekmann’s lying-in study group has had carcinoma to date one must keep in mind the reported increased risk of testicular carcinoma in testes that are or were cryptorchid. A 25-year-old man who was not part of the study group was treated recently by us for a testicular carcinoma ( mixed anaplastic seminoma plus embryonal cell carcinoma) and he had a history of diethylstilbestrol exposure in utero and cryptorchidism.

Sources: NCBI, J Urol. 1979 Jul;122(1):36-9., PMID: 37351, Association of diethylstilbestrol exposure in utero with cryptorchidism, testicular hypoplasia and semen abnormalities.

Related posts:

More DES DiEthylStilbestrol Resources

Born With a Junk Food Deficiency

How Flaks, Quacks & Hacks Pimp the Public Health

A Public Health Book by Martha Rosenberg

This hard-hitting exposé blows the lid off of everything you thought you knew about Big Pharma and Big Food. What goes on behind the scenes in these industries is more suspicious, more devious, more disreputable than you could have ever imagined.

Martha Rosenberg’s message is clear: the pharmaceutical and agricultural industries are tainting public health through marketing disguised as medical education and research, aggressive lobbying, and high-level conflicts of interest. If you’re concerned about the safety of the drugs you take and the food you eat, you owe it to yourself to read Born With a Junk Food Deficiency book.

  • Why is a drug tainted by eight corruption scandals, two illegal marketing settlements, and escalating troop deaths still a best seller—with sales actually increasing 700 percent in the 2000s?
  • Why were the dangerous side effects of a drug frequently prescribed to soldiers kept hush-­hush in order to please Wall Street?
  • Why have Big Pharma, the government, and the medical establishment turned a blind eye to patients who fall victim to suicide as a result of antidepressants and other psychoactive drugs?
  • Why are women given largely unnecessary bone scans to help sell Big Pharma drugs that are linked to jawbone deterioration, esophageal cancer, and the very fractures the drugs are supposed to prevent?
  • Why was the Teflon Chicken Don—a man who was allegedly responsible for the biggest egg recall in US history in 2010 and nine related deaths, and who was cited with health, safety, and environmental violations since 1977—never punished and allowed a gracious retirement?
  • Why are Americans unwittingly eating beef, pork, and poultry raised with a growth-producing asthma drug—a drug perceived as so dangerous it has been banned in 160 countries—that is not withdrawn from the animals’ systems prior to slaughter?

Having gained the trust of more than twenty doctors, researchers, and experts who were willing to come forward and finally tell all, reporter and editorial cartoonist Martha Rosenberg presents us with her shocking findings. Explosive material from whistle-blowers, scientists, unsealed lawsuits, and Big Pharma’s and Big Food’s own marketers exposes how these industries put profits before public safety and how the government puts the interests of business before the welfare of consumers, creating a double whammy that “pimps” the public health.

What Rosenberg reveals about government complicity, regulatory food- and drug-safety lapses, and legislative injustices will both shock and appall.

  • Why have federal meat inspectors become pathetic figureheads in the nation’s slaughterhouses, laughed at by plant managers?
  • Why are medical articles that have been exposed in lawsuits as fraudulent still standing and not retracted?
  • Why was meat possibly containing the United States’ first mad cow sold to five California restaurants when the government said it wasn’t?
  • Why are parents giving their one-year-olds acid reflux medications and their three-year-olds bipolar disorder medications?

You’ll find the answers to these and many more disturbing questions in this revealing book.

Sources: AmazonCustomer Reviews.
Find Martha Rosenberg on HuffingtonPost, Facebook, Twitter.

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When a Mom becomes her own Daughter’s Surrogate at 58 Years Old

Julia is carrying her daughter’s daughter!

I'm carrying my daughter's daughter! Grandmother, 58, is 32-year-old daughter's surrogate after she suffered a DOZEN failed pregnancies
Personal Stories

A Utah grandmother became a surrogate mother to give her daughter and son-in-law the baby they so desperately wanted.
Julia Navarro, the 58-year-old grandmother, is carrying her granddaughter for her 32-year-old daughter Lorena McKinnon who struggled through three years of failed pregnancies.

When one potential surrogate dropped out, Lorena’s mother Julia Navarro stepped up to volunteer.

At 58, she had to go through three months of hormone treatment to get her body ready for baby. The embryo took on first try and Julia is now just weeks away from being a grandmother for the first time.

Read I’m carrying my daughter’s daughter! Grandmother, 58, is 32-year-old daughter’s surrogate after she suffered a DOZEN failed pregnancies, The Daily Mail, 7 January 2014.  Find out more about Fertility – IVF – Pregnancy – Recurrent Miscarriages – Surrogacy.

Sadly for many DES daughters having their own children is not possible! Many of us who have experienced miscarriages, want to have kids but are struggling or unable to…

Significant Increase in Incidence Rates for all Cancers in UK

Rise of 23% in males and 43% in females

The European age-standardised (AS) incidence rates for all cancers in Great Britain increased by 23% in males during the period 1975-1977 to 2009-2011 (from 351.8 per 100,000 to 431.6 per 100,000) and by 43% in females (from 263.3 per 100,000 to 377.1 per 100,000), with almost this entire rise occurring before the late 1990s. Over the last ten years in Great Britain (between 2000-2002 and 2009-2011), the AS incidence rates increased by just 3% in males and 7% in females.

Trends in cancer incidence in Great Britain
1975-2011 Trends in cancer incidence in Great Britain – sources @CR_UK

More Information and Press Releases:

Phthalates Infographic

Join the “Mind the Store” campaign for safer chemicals

Phthalates are commonly found in:
Sources: Mind the Store by @SaferChemicals

Potential health effects include adverse effects on development of male reproductive system :

  • Infertility.
  • Decreased sperm count.
  • Undescended testes.
  • Malformation of the penis.

Sources: Mind the Store by SaferChemicals, a national coalition of parents, health advocates, enviros, cancer survivors and 450 organizations working to protect American families.

All our posts about BPA – Endocrine Disruptors – Pesticides – Phthalates – Men’s Health

On Flickr®

  • Watch the Diaporama, and the DES research photo set on DES Diethylstilbestrol's photostream on Flickr
  • If you already have a flickr® account, add us as a contact.
    Email your photos to des.daughter@gmail.com with a short description and title :-)

How Drug Marketing undermines Patient Safety and Public Health

The Inverse Benefit Law

Abstract

The inverse benefit law highlights the need for comparative effectiveness research and other reforms to improve evidence-based prescribing.

Recent highly publicized withdrawals of drugs from the market because of safety concerns raise the question of whether these events are random failures or part of a recurring pattern. The inverse benefit law, inspired by Hart’s inverse care law, states that the ratio of benefits to harms among patients taking new drugs tends to vary inversely with how extensively the drugs are marketed.

The law is manifested through six basic marketing strategies:

  1. reducing thresholds for diagnosing disease,
  2. relying on surrogate endpoints,
  3. exaggerating safety claims,
  4. exaggerating efficacy claims,
  5. creating new diseases,
  6. and encouraging unapproved uses.

The inverse benefit law highlights the need for comparative effectiveness research and other reforms to improve evidence-based prescribing.

NCBI Sources:

All our posts tagged Big Pharma – Doctors – Drug Money –Medical Representatives – Pharmaceutical Industry

France Procès Distilbène: une Sarthoise dénonce UCB Pharma

Carnet de Santé sur France Inter

10 janvier 2014 – Interview de Sylvie Le Cossec

La vie de Sylvie a été ravagée par le Distilbène, cette hormone de synthèse prescrite à sa mère et supposée éviter les fausses couches.

Deux grossesses pathologiques, un fils polyhandicapé à la vie dévastée, une carrière internationale stoppée, une vie de couple bouleversée, un cancer de l’utérus, un quotidien difficile à gérer… Sylvie publie son livre “Distilbène, Mon Fils n’aura Jamais son Bac” et dénonce le laboratoire UCB Pharma.

Le Distilbène DES, en savoir plus
Listes d’enregistrements sur SoundCloud

Catch-22: Clinical Trials Edition

Hilda Bastian is cartoonist and writer at StatisticallyFunny blog

It’s the Catch-22 of clinical trials: to protect pregnant women and children from the risks of untested drugs….we don’t test drugs adequately for them.

Catch-22: Clinical Trials Edition
Women and children overboard, by @HildaBast

In the last few decades, we’ve been more concerned about the harms of research than of inadequately tested treatments for everyone, in fact. But for “vulnerable populations,” like pregnant women and children, the default was to exclude them. ”

Hilda Bastian is Editor etc at PubMed Health, blogger at Scientific American, commenting on the science of unbiased health research with cartoons at Statistically funny.

Continue reading Women and children overboard
by Hilda Bastian, 23 April 2013

All our posts about the #AllTrials campaign. More about Big Pharma – Clinical Trials – Prescriptions Drugs – the FDA – the Pharmaceutical Industry

On Flickr®

Watch the Diaporama, and the health comics album on  DES Diethylstilbestrol's photostream on Flickr

If you already have a flickr® account, add us as a contact
Email your photos to des.daughter@gmail.com with a short description and title :-)