Prescription drugs are the fastest growing sector of US healthcare costs
American is a nation of pill poppers. Nearly 13 prescriptions were prescribed per man, woman, and child last year. We’re one of only two countries in the world who allow direct-to-consumer Rx advertising; and Rx have slowly grown to be the third highest medical cost. Welcome to the pill nation. Sources and full article on TheNursingBible and Janice_Flahiff on WordPress.
Dose-Dependent Incidence of Hepatic Tumors in Adult Mice following Perinatal Exposure to Bisphenol A
Background: Bisphenol-A (BPA) is a high production – volume chemical with hormone – like properties that has been implicated as a potential carcinogen. Early life exposure has been linked to increased risk for precancerous lesions in mammary and prostate glands and the uterus, but no prior study has shown a significant association between BPA exposure and cancer development.
Objective: We explored the effects of exposure to BPA during gestation and lactation on adult incidence of hepatic tumors in mice.
Methods: Isogenic mice were perinatally exposed to BPA through maternal diets containing one of four environmentally relevant doses (0, 50 ng, 50 µg, or 50 mg of BPA per kg diet) and approximately one male and one female per litter were followed until 10 months of age. Animals were tested for known risk factors for hepatocellular carcinoma, including bacterial and viral infections.
We report dose-dependent incidence of hepatic tumors in exposed 10-month mice. 23% of offspring presented with hepatic tumors or preneoplastic lesions. A statistically significant dose-response relationship was observed, with an odds ratio for neoplastic and preneoplastic lesions of 7.23 (95% CI: 3.23, 16.17) for mice exposed to 50 mg BPA per kg diet compared with unexposed controls. Observed early disease onset, absence of bacterial or viral infection, and lack of characteristic sexual dimorphism in tumor incidence support a non-classical etiology.
To our knowledge, this is the first report of a statistically significant association between BPA exposure and frank tumors in any organ. Our results link early life exposure to BPA with the development of hepatic tumors in rodents, with potential implications for human health and disease.
Food packaging chemicals may be harmful to human health over long term, will epidemiologists rise to the neotoxic challenge?
” The synthetic chemicals used in the packaging, storage, and processing of foodstuffs might be harmful to human health over the long term, warn environmental scientists. This is because most of these substances are not inert and can leach into the foods we eat, they say. Despite the fact that some of these chemicals are regulated, people who eat packaged or processed foods are likely to be chronically exposed to low levels of these substances throughout their lives. And far too little is known about their long term impact. ”
Recent Studies and Press Releases;
The Journal of Epidemiology and Community Health doi:10.1136/jech-2013-202593, Food packaging and migration of food contact materials: will epidemiologists rise to the neotoxic challenge?, 19 Feb 2014
Food packaging chemicals may be harmful to human health over long term, ScienceDaily, 19 Feb 2014
Chemicals leaching into food from packaging raise safety concerns, The Guardian, 19 Feb 2014
Le viticulteur bio qui ne voulait pas traiter ses vignes…
Emmanuel Giboulot, viticulteur bio, a été convoqué le 24 février au tribunal de Dijon (Côte-d’Or). Il encourait 30 000 euros d’amende et six mois d’emprisonnement pour avoir refusé de traiter ses vignes dans le cadre de la lutte obligatoire contre la flavescence dorée. Un témoignage poignant…
” Contrary to cultural assumptions that boys are stronger and sturdier, basic biological weaknesses are built into the male of our species. These frailties leave them more vulnerable than girls to life’s hazards, including environmental pollutants such as insecticides, lead and plasticizers that target their brains or hormones. Several studies suggest that boys are harmed in some ways by these chemical exposures that girls are not. It’s man’s fate, so to speak. ”
” Margaret McCartney is diligent enough to dig deep into the evidence, brave enough to name names where necessary and lucid enough to capture a concept in a memorable sentence.
Welcome to the world of sexed-up medicine, where patients have been turned into customers, and clinics and waiting rooms are jammed with healthy people, lured in to have their blood pressure taken and cholesterol, smear test, bowel or breast screening done.
In the world of sexed-up medicine pharmaceutical companies gloss over research they don’t like and charities often use dubious science and dodgy PR to ‘raise awareness’ of their disease, leaving a legacy of misinformation in their wake. Our obsession with screening swallows up the time of NHS staff and the money of healthy people who pay thousands to private companies for tests they don’t need. Meanwhile, the truly sick are left to wrestle with disjointed services and confusing options.
Explaining the truth behind the screening statistics and investigating the evidence behind the hype, Margaret McCartney, an award-winning writer and doctor, argues that this patient paradox – too much testing of well people and not enough care for the sick – worsens health inequalities and drains professionalism, harming both those who need treatment and those who don’t. “
Almost every time someone wants to proclaim the US to be the “best in the world” in health care, they point to survival rates. The metric people should be using is mortality rates…
Survival rates refer to the percent of people who live a certain amount of time after they’ve been diagnosed with a disease. But there are real problems in using survival rates to compare the quality of care across systems.
Le cancer fait l’objet de toutes les attentions, notamment en matière de dépistage. Au risque parfois d’entraîner des traitements excessifs altérant souvent de manière irréversible la qualité de vie…
” Pendant des décennies, il a été affirmé péremptoirement et sans preuve scientifique que plus le diagnostic d’un “cancer” était précoce plus on avait de chances d’en guérir. Cet argument était peut être vrai dans les années 60 lorsque le traitement se résumait à la chirurgie et qu’on ne guérissait guère plus de 30% de malades mais il ne l’est pas aujourd’hui. Le dépistage organisé a transformé des monceaux de gens normaux, chez lesquels on a trouvé quelques cellules malignes, en cancéreux. Ils ont subi examens complémentaires, opérations et traitements médicaux (chimiothérapie) et/ou radiothérapie et ont été ensuite déclarés “guéris”ep. Cela a permis de faire croire à une épidémie galopante du cancer et en même temps aux progrès rapides de la médecine puisque le taux de guérison des cancers augmentait également très vite (on guérit facilement les cancers qui n’évoluent pas) . Beau doublé ! “
Nicole Delépine est responsable de l’unité d’oncologie pédiatrique de l’hôpital universitaire Raymond Poincaré à Garches. Fille de l’un des fondateurs de la Sécurité Sociale et thérapeute engagée, elle a récemment publié La face cachée des médicaments et Le cancer, un fléau qui rapporte.