This book should be in every school, and every medical waiting room says Ben Goldacre
The 2nd edition of Testing Treatments was published in 2011. It urges everyone to get involved in improving current research and future treatment, and outlines practical steps that patients and health professionals can take together to do this.
How do we know whether a particular treatment really works? How reliable is the evidence? And how do we ensure that research into medical treatments best meets the needs of patients? These are just a few of the questions addressed in a lively and informative way in the free book written by Imogen Evans, Hazel Thornton, Sir Iain Chalmers and Paul Glasziou.
The full text of the 2nd edition is available for free download, and the paperback and ebook editions can be purchased from the publisher or from online booksellers. The text is already available in some other languages, and translations into additional languages are being prepared.
Hilda Bastian is cartoonist and writer at StatisticallyFunny blog
” … many people – including many doctors – just love gadgets and measuring things… … Actually, there’s too much monitoring in some health matters. Some monitoring could cause anxiety without benefit, or lead to actions that do more harm than good. “
Hilda Bastian is Editor etc at PubMed Health, blogger at Scientific American. Commenting on epidemiology with cartoons at Statistically funny.
More the opposite: DES-exposure in utero led to increased rate of miscarriage and preterm birth
Oestrogen supplementation, mainly diethylstilbestrol, for preventing miscarriages and other adverse pregnancy outcomes
Laboratory evidence in the 1940s demonstrated a positive role of placental hormones in the continuation of pregnancy. It was suggested that diethylstilbestrol (DES) was the oestrogen of choice for prevention of miscarriages. Observational studies were carried out with apparently positive results, on which clinical practice was based. This led to a worldwide usage of diethylstilbestrol despite controlled studies with contrary findings.
To determine the effects of antenatal administration of oestrogens, mainly diethylstilbestrol, on high risk and unselected pregnancy as regards miscarriages and other outcomes.
We searched the Pregnancy and Childbirth Group Specialised Register of controlled trials in November 2002.
Randomised and quasi-randomised trials were included.
DATA COLLECTION AND ANALYSIS:
Both reviewers extracted data from the studies identified that met the selection criteria, and the data were analysed using the RevMan software.
REVIEWER’S CONCLUSIONS: There was no benefit with the use of diethylstilbestrol in preventing miscarriages. Both short and long-term adverse outcomes in exposed offsprings were demonstration of the harm that this intervention caused women and their offspring during its usage.
NCBI, Oestrogen supplementation, mainly diethylstilbestrol, for preventing miscarriages and other adverse pregnancy outcomes, PMID: 12918007, 2003;(3):CD004353.
While there may be some phone apps you can live without, there are some that can keep you healthy ! Check out seven apps that could benefit your health
When it comes to your phone, do you suffer from app overload? While there may be some phone apps you can live without, there are some that can keep you healthy! Check out seven apps that could benefit your health.
A convincing sales pitch appeared in 1957, right in the middle of the thirty-three year period between 1938 and 1971 during which Diethylstilbestrol (DES) was prescribed regularly under various brand names
“Yes! desPLEX to prevent abortion miscarriage and premature labor. Recommended for routine prophylaxis in ALL pregnancies! Ninety-six percent live delivery with desPLEX in one series of 1200 patients – bigger and stronger babies, too. No gastric or other side effects with desPLEX – in either high or low dosage.”
This convincing sales pitch appeared in 1957, right in the middle of the thirty-three year period between 1938 and 1971 during which Diethylstilbestrol (DES) was prescribed regularly under the brand names Estrosyn, Palestrol, Domestrol, and more.
If April doesn’t suit, please choose a more suitable day and make that your Go Blue for Autism day!
Each year on April 2, World Autism Awareness Day, iconic buildings across Australia and the world turn their lights blue to promote autism awareness. In support of this global initiative, Autism Queensland asks people Go Blue for the month of April to help raise awareness and funds to help us support Queenslanders of all ages living with ASD and their families.