Discover Sckoon Menstrual Cup: Clean, Effective Alternative to Tampons or Disposable Pads

Your period should be a breeze, and with an internally worn menstrual cup, it should be

Your period should be a breeze, and with SckoonCup, an internally worn menstrual cup, it will be. Discover a clean, effective alternative to tampons or disposable pads. Made from FDA approved soft medical-grade silicon, it’s safe, reusable, environmentally friendly, and pretty, too!

Sources

Les étudiants en médecine sont-ils trop tournés vers le business des labos pharmaceutiques?

Futurs médecins : la formation aux médicaments est bâclée

Le Nouvel Observateur, le média nouvelle génération engagé.

Selon le mensuel
Que-Choisir N°525
” Médecins, La formation aux médicaments est bâclée “,
les futurs médecins connaissent un peu trop mal les médicaments et… un peu trop bien les commerciaux des labos pharmaceutiques…

  • Cours “saucissonnés”
  • Commerciaux très envahissants

Lire Etudiants en médecine : zéro pointé sur les médocs,
Le Nouvel Observateur, education/20140505.OBS6128,
par Arnaud Gonzague, le 05 mai 2014

Toxic Chemicals in Cosmetics and the Real Cost of Beauty

@chemicalsinhome is educating the world on safer products for the home

Get familiar with the toxic chemicals in cosmetics with this great infographic first shared by Cosmotology .org.
You’ll learn, for example, that 1 in 3 brands of red lipstick tested by the FDA contain more lead then the FDA’s acceptable upper limit for candy…

Toxic Chemicals in Cosmetics infographic
See the original size (640 x 4288) – via @chemicalsinhome – on Flickr

Sources: ChemicalsInTheHome, MARCH 20, 2013

On Flickr®

Full Moon Engage Me Social Media Event – Empire Avenue Leaders #FullMoonEngageMe #SocialNetworking

Wednesday 28th of May – join our NEW social media event taking place at the Full Moon – via #EAv – and give a boost to your social networking! #FullMoonEngageMe #SocialMedia #SocialNetworking

The incredible Opportunity

It was via an important letter to our Community that Empire Avenue (EAv) announced their new “Ultimate Leaders Upgrade‘ . Since the special package includes […all Pies Upgrades, 500 Extra Even More Desserts, 20 Promoted and 20 Scheduled Missions, 5 Million Eaves cash, extra Eaves whenever members complete each others’ missions, double dividends on social stocks from each other and more… ] it was quickly nicknamed as “The NoBrainer“… The interest generated was instant, confirmed by Empire Avenue Leaders reaching 500 members in no time.

When EAv Leaders show they are

empire avenue leaders logo
Empire Avenue Leaders badge displayed on some EAv profiles

In April 2014, the Leaders started running EAv’s marketing, recruitment, and retention programs. Okay, the technical staff continues to support the platform, manage the database, and provide normal tech support but EAv clearly became the first social media network run by members, for members. I have been genuinely impressed by the amount of devotion, time, energy, skills and efforts dedicated by many EAv Leaders, completely justifying the initial name chosen for the group.

How the EAv Leaders fit in the #FullMoonEngageMe SoMe Event

All EAv members are invited to join the Full Moon Engage Me Social Media Event. Remember, the reasons for the event are much rather for a fruitful let’s connect time than for a buy-me boost… Therefore the event will be an ideal opportunity for anyone considering to join the Leaders to ask specific questions (such as measurable benefits, time saved, etc.) – directly to Leaders joining the SoMe event – in a non-judgemental community where we hope everyone will feel completely relaxed.

Is there still Life outside the EAv Leaders?

Yes there is! And, would some EAv players feel that the game is getting too hard… and/or in the unlikely event that some non regular players would feel there is not much left for the non Leaders… the FullMoon EngageMe Social Media Event community will be exclusively opened to the regular players! By doing so, we hope that the missions launched by the SoMe event hosts will help the EAv players in need of even more support.
As a reminder, everyone has access to the Gangstas community which is where the EAv event takes place. The Leaders have agreed to support the event with publicity and missions too.

More information
  • #FullMoonEngageMe SoMe Event – Announcement
  • #FullMoonEngageMe SoMe Event – Let’s Connect.
  • #FullMoonEngageMe SoMe Event – The Hosts.
  • #FullMoonEngageMe SoMe Event – The Reasons.
  • Please use the comment section to ask any question about the event.
  • You can join – for FREE – Empire Avenue at anytime – before and after the first FullMoon EngageMe Social Media Event.
    You can use this link – with no strings attached – to get some extra “eaves” at start !
    See you soon 🙂

Estrogen Receptor-α mediates DES-induced Feminization of the Seminal Vesicle in Male Mice

These data suggest that DES-induced SV toxicity and feminization are primarily mediated by Estrogen Receptor-α; however, some aspects of androgen response may require the action of ERβ

Abstract

image of PubMed NCBI The Endocrine Society logo
Feminization of the male mouse reproductive tract after prenatal exposure to Diethylstilbestrol.

BACKGROUND:
Studies have shown that perinatal exposure to the synthetic estrogen diethylstilbestrol (DES) leads to feminization of the seminal vesicle (SV) in male mice, as illustrated by tissue hyperplasia, ectopic expression of the major estrogen-inducible uterine secretory protein lactoferrin (LF), and reduced expression of SV secretory protein IV (SVS IV).

OBJECTIVES:
The present study was designed to evaluate the role of the estrogen receptor (ER) in this action by using ER-knockout (ERKO) mice.

METHODS:
Wild-type (WT), ERα-null (αERKO), and ERβ-null (βERKO) male mice were treated with either vehicle or DES (2 μg/day) on neonatal days 1-5. These mice were divided into two groups: In the first group, intact mice were sacrificed at 10 weeks of age; in the second group, mice were castrated at 10 weeks of age, allowed to recover for 10 days, treated with dihydrotestosterone (DHT) or placebo, and sacrificed 2 weeks later. Body weights and SV weights were recorded, and mRNA expression levels of Ltf (lactoferrin), Svs4, and androgen receptor (Ar) were assessed.

RESULTS:
In DES-treated intact mice, SV weights were reduced in WT and βERKO mice but not in αERKO mice. DES-treated WT and βERKO males, but not αERKO males, exhibited ectopic expression of LF in the SV. DES treatment resulted in decreased SVS IV protein and mRNA expression in WT males, but no effect was seen in αERKO mice. In addition, DES-treated βERKO mice exhibited reduced Svs4 mRNA expression but maintained control levels of SVS IV protein. In DES-treated castrated mice, DHT implants restored SV weights to normal levels in αERKO mice but not in WT mice, suggesting full androgen responsiveness in αERKO mice.

CONCLUSIONS:
These data suggest that DES-induced SV toxicity and feminization are primarily mediated by ERα; however, some aspects of androgen response may require the action of ERβ.

Sources:
  • Estrogen receptor-α mediates diethylstilbestrol-induced feminization of the seminal vesicle in male mice, NCBI, PMID: 22275727, 2012 Apr;120(4):560-5. doi: 10.1289/ehp.1103678. Epub 2012 Jan 24.
  • Additional article information, full text PMC, /articles/PMC3339448/, Apr 2012; 120(4): 560–565. PDF
More DES DiEthylStilbestrol Resources

Full Moon Engage Me Social Media Event – The Hosts #EAv #FullMoonEngageMe #SocialNetworking

Wednesday 28th of May – join our NEW social media event taking place at the Full Moon – via #EAv – and give a boost to your social networking! #FullMoonEngageMe #SocialMedia #SocialNetworking

FullMoon EngageMe Community Admins

full-moon-admins image
Meet the “FullMoon EngageMe Social Media Event” EAv community admins

Meet Your Hosts!

(e)CFLEURY: Founder and managing director of Intechrate. Independent technology consulting, social marketing.

(e)CYGU38: A French guy in Belgium, programme manager at MCA BENELUX, kind of technoholic.

(e)DAYTRADER: is from Québec. Dany buys and sells stock on the New York stock market, he is a day trader in real life.

(e)DESDAUGHTER: Activist, blogger for health news about worldwide prescription drugs issues, cancer, pharma, EDCs.

(e)DOMINOCEAN: Manager, Project AWARE EMEA Office. Fascinated by the power of social media and its effect on society!

(e)HARRIE: Hudson Valley Digital Revenue Design. Ellen is examiner for Business Accelerated, management consulting.

(e)JAYM: Enterprise-level web dev manager, internet marketing veteran, occasional blogger and consummate entrepreneur.

(e)NORTHLANDFOX: Social media emergency management and preparedness globally various hobbies and other volunteer interests.

(e)PROMOTE4YOU: Your global business connector. Gerrit offers one month free trial on his Promote4you Network.

(e)SEBAB: Social media enthusiast, SEO consultant. Student of advanced GoogLOLogy. Social and anti-social media strategist.

More information
  • #FullMoonEngageMe SoMe Event – Announcement.
  • #FullMoonEngageMe SoMe Event – The Reasons.
  • #FullMoonEngageMe SoMe Event – Let’s Connect.
  • Please use the comment section to ask any question about the event.
    Stay tuned ! more posts with more details soon !
  • You can join – for FREE – Empire Avenue at anytime – before and after the first FullMoon EngageMe Social Media Event.
    You can use this link – with no strings attached – to get some extra “eaves” at start !
    See you soon 🙂

Procès Distilbène 2014: la Victoire de Sandrine Jean contre le labo Novartis se précise

Le tribunal de Nanterre a condamné le laboratoire Novartis. Concernant le préjudice financier, le délibére a été fixé au 3 juillet 2014

image de Sandrine Jean
Sandrine souriante à la sortie du tribunal de Nanterre, hier après-midi

Le procès de Sandrine a duré 3 ans jusqu’à présent. Sandrine – représentée par Maître Verdier – a un utérus typique distilbène deuxième génération et avait également les ordonnances à l’appui – de la prescription du distilbène à sa mère.

Sandrine a refusé une somme à l’amiable – de Novartis – afin d’aller jusqu’au procès.
L’avocat de Novartis a reconnu qu’en 15 ans – de plaidoiries pour Novartis – ce n’est que la deuxième fois que cela aille jusqu’au procès…
la plupart des poursuites se termineraient donc à l’amiable…

Concernant le préjudice financier, le délibéré a été fixé au 3 juillet 2014.

Le Distilbène DES, en savoir plus

Procès Distilbène : le labo UCB Pharma à nouveau condamné

Victoire de Stéphanie Chevallier ! Le tribunal de Nanterre a condamné le laboratoire UCB Pharma à lui verser plus de 130 000 euros de dommages et intérêts

stephanie chevallier
Stéphanie est présidente de l’association
Les Filles DES

Stéphanie Chevallier – auteure du livre Moi, Stephanie, Fille DistilbèneLe Scandale de la Maternité volée… , présidente de l’association Les Filles DES,  dont voici une vidéo d’archive 2009 – a été pleinement reconnue comme victime par le Tribunal de Nanterre après plus de neuf ans d’attente au total.

A cause de son exposition in utero au Distilbène, Stéphanie souffre de problèmes de stérilité et de malformations utérines qui l’ont notamment privée du bonheur de donner la vie. En 2005, elle engage une procédure judiciaire contre le laboratoire UCB Pharma qui commercialisait le DES. Son procès n’aura pas lieu car UCB Pharma fait annuler la demande d’expertise médicale en appel. Puis, en 2009, la Cour de Cassation annonce qu’il est interdit de faire appel d’une telle demande. Le dossier de Stéphanie peut donc être plaidé et jugé. Mais la lenteur de la justice française la contraint à attendre cinq ans de plus pour que le procès s’ouvre enfin.

Aujourd’hui 22 mai 2014 , la justice à condamné le laboratoire UCB Pharma à lui verser plus de 133 000 euros de dommages et intérêts…

Le Distilbène DES, en savoir plus

New AntiCancer Compound discovered using accelerated Drug Screening Process

A team of research scientists from VTT Technical Research Centre of Finland, the University of Turku and the University of Eastern Finland has discovered a previously unknown Cent-1 molecule that kills cancer cells

VTTFinland logo
VTT Technical Research Centre of Finland. Technological breakthroughs for a clean world, sustainable economy, good life – and new business!

A previously unknown Cent-1 molecule that kills cancer cells has been discovered by scientists.
The objective of the research was to accelerate the drug development process by identifying new compounds that would possess similar binding properties and cellular phenotype, but a different chemical structure, as the selected drugs in clinical use or investigational compounds in development.
The scientists combined computer-based screening and cell-based assays to create a method that can significantly accelerate drug discovery and thereby lower development costs.

Sources
  • Finnish researchers discovered a new anticancer compound using accelerated drug screening processVTT Technical Research Centre of Finland, News, 08.05.2014.
  • Centmitor-1, a Novel Acridinyl-Acetohydrazide, Possesses Similar Molecular Interaction Field and Antimitotic Cellular Phenotype as Rigosertib, ON 01910.Na , American Association for Cancer Research, 13/5/1054 10.1158/1535-7163.MCT-13-0685, May 2014 13.

Screening Tests : You have the Right to remain Anxious

The National Cancer Institute’s Barry Kramer tackled the issue of over-diagnosis from cancer screening

Drive-thru screening clinic image
Screening Tests #comics by @HildaBast on Flickr

Hilda Bastian is Editor etc at PubMed Health, blogger at Scientific American. Commenting on epidemiology with cartoons at Statistically funny.

Read You have the right to remain anxious…. by Hilda Bastian.

See more comics – all our posts tagged overdiagnosis and screening.

On Flickr®

Watch the Diaporama, and the health comics set on  DES Diethylstilbestrol's photostream on Flickr

If you already have a flickr® account, add us as a contact
Email your photos to des.daughter@gmail.com with a short description and title :-)