The Inherited Risk of Breast and Ovarian Cancer

Studies have shown that a person’s genes can cause an increased risk in breast and ovarian cancer

Studies have shown that a person’s genes can cause an increased risk in breast and ovarian cancer. This infographic shows the chromosomal mutations and the risk they can pose.
According to the National Cancer Institute, studies have shown that inherited mutations in the BRCA1 and BRCA2 genes account for 5-10 percent of all breast cancers and 15 percent of all ovarian cancers. While genetic testing is encouraged only for those who have a family history of breast or ovarian cancer, education and awareness are important to early detection and treatment.
How can a better understanding of the cause of these genetic mutations help further the cause of finding a cure for cancer?

The Inherited Risk of Breast and Ovarian Cancer infographic
Studies have shown that a person’s genes can cause an increased risk in breast and ovarian cancer – an Infographic via @SUMedicine
Sources:
More Information:
On Flickr®

The FDA and the Drug Companies are in Bed Together

Pharmaceuticals, The Real Druglords… a video interview with Dr Ron Paul

Interview of Dr Ron Paul, advocate for freedom and former member of the U.S. House of Representatives.

Effects on the Menstrual Cycle of in Utero Exposure to DiEthylStilbestrol

DiEthylStilbestrol usage review buttress the need for adequate and rigorous research into the use of drugs in pregnancy and ensure that they do more good than harm before being introduced

Abstract

image of PubMed NCBI The Endocrine Society logo
DiEthylStilbestrol usage review buttress the need for adequate and rigorous research into the use of drugs in pregnancy and ensure that they do more good than harm before being introduced for consumption.

OBJECTIVES:
The purpose of this study was to determine the effects of in utero exposure to diethylstilboestrol on the menstrual cycle.

STUDY DESIGN:
This was a prospective cohort study of 198 diethylstilbestrol-exposed women and 162 unexposed controls, recruited from women whose mothers participated in a randomized trial of diethylstilbestrol in pregnancy at the Chicago Lying-In Hospital from 1950 to 1952. Women with severe menstrual abnormality were excluded from the study.

RESULTS:
Diethylstilbestrol exposure was associated with a statistically significantly decreased duration of menstrual bleeding of approximately one half day and a lower average daily bleeding score (self-reported). We found no evidence for effects of diethylstilbestrol exposure on cycle length or variability of cycle length. Exposure was not related to symptoms of dysmenorrhea.

CONCLUSIONS:
The decreased duration and amount of menstrual bleeding among diethylstilbestrol-exposed women could be due to direct effects on the uterus. The lack of an effect on cycle length and variability appears to indicate that endocrine function is not grossly disturbed in those women studied.

Sources:
  • Effects on the menstrual cycle of in utero exposure to diethylstilbestrolNCBI, PMID: 8141188,
    Am J Obstet Gynecol. 1994 Mar;170(3):709-15.
  • Full text: American Journal of Obstetrics and Gynecology, S0002937894702683, DOI: 10.1016/S0002-9378(94)70268-3.
More DES DiEthylStilbestrol Resources

What is really in Your Chicken Sandwich?

The United States of Progesterone

Console & Hollawell Twitter logo
Attorney Richard Console lays out the case for avoiding hormone-laden chicken in favor of pastured, GMO-free birds.

Most people would assume the package of chicken they are purchasing in the meat department at the grocery store is simply that – chicken. However, with most chicken and other meat products in our stores and on our plates that is not the case; they are highly processed, genetically modified, and full of ingredients you would never want associated with the the food you are about to ingest.

  • The Scandalous Evolution of Animal Protein
  • Frankenstein’s Monster in Your Grocer’s Freezer
  • The Economics of Our Food
  • The Dirty Ingredients in Cheap Meats

Read The United States of Progesterone: What’s Really in Your Chicken Sandwich, Console & Hollawell Blog
 law-blog, by Richard Console, March 6, 2013

Epidemiology of Women’s Health, Book covering some of DES Conditions

Students assigned this excellent textbook are reading about DES – with info sprinkled liberally throughout

Epidemiology Of Women's Health book cover image
The Department of Epidemiology @ColumbiaMSPH brings a broad cells-to-society approach to population health research and a commitment to translation.

by Ruby T. Senie, PhD, Professor of Clinical Public Health, Columbia University, New York

With contributions from leading authorities in the field, this one-of-a-kind text explores the major health challenges and conditions specifically affecting women. Epidemiology of Women’s Health covers chronic, infectious, autoimmune and psychological conditions as well as the health disparities and differences in health behaviors to give the reader a comprehensive understanding of the major female-specific needs that may be useful in developing effective public health programs. The text concludes with a review of the ethical aspects of gender-specific research studies. Divided into 10 sections, the book covers the following topic areas: Introduction to Epidemiology of Women’s Health; Personal and Community-Based Health Promotion and Morbidity Prevention; Sexual Health Across the Life Span; Sexually Transmitted Infections; Chronic Psychological and Psychosocial Conditions; Endocrine & Autoimmune Conditions; Malignancies; Chronic Conditions; Aging; and Impact of Research: Lessons from the Past, Challenges of the Future.

DES Action USA published this comment:
Students assigned this excellent textbook are reading about DES – with info sprinkled liberally throughout. Chapter 26 is even dedicated to the memory of a DES Daughter who died of breast cancer. Inside tip: turn to page 473 to see a picture of the author, Rubie Senie. We thank her for keeping DES front and center! – See book contents.

On Flickr®
More DES DiEthylStilbestrol Resources

Thalidomide – The Fifty Year Fight

After 52 years of injustice this is the Thalidomide survivors’ campaign against the German government and thalidomide manufacturer Grunenthal

the fifty year fight image
If you’re a member of the public and would like to help please contact both your MP and MEP to let them know you’re fully supportive and ask them to help the Campaign.

After 52 years of injustice this is the Thalidomide survivors’ campaign against the German government and thalidomide manufacturer Grunenthal.

FiftyYearFight.org Overview:

  • Why the Fifty Year Fight?
  • History
  • Timeline
  • Press Release – June 2014 – New Evidence
  • Health Reports Downloads
  • HOW YOU CAN GET INVOLVED
  • Meet Kevin, a Thalidomide survivor born without arms and legs
  • Meet Liz, Thalidomide survivor born without arms below the elbow

Visit fiftyyearfight.org and support @fiftyyearfight

A Twenty-Five-Year Follow-Up Study of Women exposed to DiEthylStilbestrol during Pregnancy

DES usage review buttress the need for adequate and rigorous research into the use of drugs in pregnancy and ensure that they do more good than harm before being introduced

Abstract

image of PubMed NCBI The Endocrine Society logo
DiEthylStilbestrol usage review buttress the need for adequate and rigorous research into the use of drugs in pregnancy and ensure that they do more good than harm before being introduced for consumption.

To assess the long-term effects of diethylstilboestrol (DES) we conducted a health survey among 693 mothers who had taken the drug during pregnancy and a comparable group of 668 who had not. These women had participated in a study during 1951-52 to evaluate the drug. There were 32 (4.6 per cent) breast cancers among the 693 exposed and 21 (3.1 per cent) among the 668 unexposed, but the difference was not statistically significant (P = 0.16). No statistically significant differences occurred between the groups in any of the other categories of disease. The occurrence of breast cancer in both groups was compared to the Connecticut State Tumor Registry for 1963-65. Compared to the registry data, a significantly (P less than 0.01) higher incidence of breast cancer occurred in both the exposed and unexposed groups at ages over 50. The reason for this increase is not known, but effects linked to the selection of mothers participating in the original clinical study cannot be excluded.

Sources:
  • A twenty-five-year follow-up study of women exposed to diethylstilbestrol during pregnancy,
    NCBI, PMID: 628409, N Engl J Med. 1978 Apr 6;298(14):763-7.
  • Full text: NEJM, 197804062981403,
    N Engl J Med 1978; 298:763-767April 6, 1978DOI: 10.1056/NEJM197804062981403
More DES DiEthylStilbestrol Resources

Prescription Drug Abuse Infographic

Via Rocky Mountain Poison and Drug Center

Prescription Drug Abuse Infographic
Sources: Rocky Mountain Poison and Drug Center – rmpdc.org
Find More Information:

All our posts about AEDsbig pharmaDESdoctorsdrug money,drugsEx Pharma Rx Drug Pusher Confessions – Gwen Olsen, the FDAmedical representativesSSRIsthalidomidevalproate. See more infographics.

On Flickr®

Pregnant Women, Breast-Feeding Women and Young Children should Eat More Fish

Eating 8 to 12 ounces per week of a variety of fish lower in mercury during pregnancy benefits fetal growth and development

Some Women and Young Children Should Eat More Fish

fda logo
Eat 8 to 12 ounces of a variety of fish each week from choices that are lower in mercury. The nutritional value of fish is important during growth and development before birth, in early infancy for breastfed infants, and in childhood.

If you’re pregnant, you’ve no doubt been given a list of foods to avoid—undercooked meat, soft cheeses made from unpasteurized milk, and alcohol, to name a few. The good news is that there is a food you should have more of while pregnant and while breastfeeding: fish and shellfish. The latest science shows that eating fish low in mercury during pregnancy and in early childhood can help with growth and neurodevelopment. It can also be good for your health.
That’s why the Food and Drug Administration (FDA) and the Environmental Protection Agency (EPA) have issued draft revised advice encouraging pregnant women, those who might become pregnant, breastfeeding mothers and young children to eat more fish—and to eat a variety of fish lower in mercury.

It’s an important recommendation. An FDA analysis of data from U.S. pregnant women surveyed about seafood consumption showed that they ate far less fish than the 2010 Dietary Guidelines for Americans recommend. (The guidelines are the federal government’s most recent science-based advice for how to choose a healthy eating pattern.) In fact, 21 percent of the pregnant women surveyed said they ate no fish in the previous month. Of the women who ate fish in the previous month, 50 percent reported eating fewer than two ounces a week, and 75 percent reported eating fewer than four ounces per week.

“We’re updating our advice because the latest science strongly indicates that eating 8 to 12 ounces per week of a variety of fish lower in mercury during pregnancy benefits fetal growth and development,” says FDA’s Acting Chief Scientist Stephen Ostroff, M.D., noting that FDA reviewed research from the last decade.

Dr. Ostroff adds that 8 to 12 ounces is an excellent range to maximize the developmental benefits that fish can provide. “The science behind that recommendation was not available when we last issued fish consumption advice in 2004.”

The 2004 advice recommends eating up to 12 ounces of fish lower in mercury per week but doesn’t recommend a minimum amount to eat. The new draft advice does, recommending that women who might become pregnant along with pregnant and breastfeeding women eat at least eight ounces and up to 12 ounces weekly, which is two to three servings. This draft advice also extends to young children, although the amounts you serve them should be proportionally smaller.

Which Fish Should You Eat?

Fish and shellfish (collectively called “fish” for this advice) have high-quality protein, vitamins and minerals, and omega-3 fatty acids. Fish also are mostly low in saturated fat, and some have vitamin D. Eating fish during pregnancy, while breastfeeding, and in early childhood can be especially important for a child’s growth and development. Plus there is evidence that consuming fish can reduce your own risk of cardiac death.
The entire package of nutrients that fish provide may be needed to fully benefit fetal and child development. For this reason, consumers who avoid eating fish and instead take omega-3 supplements may be missing out on the full beneficial effect. Plus they miss out on other nutrients in fish that support overall health.

Eating a variety of fish helps ensure that most fish you eat will be lower in mercury. Most fish found in grocery stores are, in fact, lower in mercury, including many popular species such as shrimp, pollock, salmon, canned light tuna, tilapia, catfish and cod.

What about Mercury in Fish?

Fish do take in methylmercury (a form of mercury), and nearly all fish have traces of it. At high levels, methylmercury can be harmful, and developing fetuses can be especially sensitive to it. Young children may be sensitive as well. Some women may even limit or avoid fish because of this concern. That, however, is not what FDA and EPA recommend.
Eating a variety of fish, as FDA and EPA are recommending, will help ensure that most fish you eat will be lower in mercury. However, FDA and EPA are also recommending that women who might become pregnant, or who are pregnant or breastfeeding—along with young children—should try to avoid the four types of commercial fish with the highest levels of methylmercury: Tilefish from the Gulf of Mexico, shark, swordfish and king mackerel. This advice shouldn’t affect your eating patterns because these fish are not popular on the market.

Also remember that most fish found in grocery stores are lower in mercury, and it is these fish that have health benefits for you and your children.

Other Considerations

FDA and EPA continue to recommend that no more than six ounces of fish per week (of your 8 to 12 ounces weekly) should be white (albacore) tuna. Although canned light tuna is lower in mercury, albacore tuna has more of it. An easy way to follow this advice? Just vary the types of fish that you eat, per the overall recommendations.
And if you or someone you know goes fishing in a lake, stream, or river, follow local fish advisories. If local advice isn’t available, you should eat six ounces or less of these locally caught fish per week, and children should eat no more than one to three ounces per week. Then avoid eating other fish for the rest of the week.

The Bottom Line

“The science shows that eating fish has direct health benefits, so it’s important to get enough fish in your diet,” Ostroff says. “To obtain the health and nutrition benefits of fish, stick to the advice we’re offering, and have 8 to 12 ounces of fish lower in mercury per week as part of a balanced eating plan.”
This advice will be open for public comment, and FDA encourages feedback. See the notice of availability that published in the Federal Register for more information regarding how to submit comments.

Sources and More Information
  • New Advice: Some Women and Young Children Should Eat More Fish, FDA Consumer Updates, ucm397443, 06/10/2014.
  • FDA and EPA issue draft updated advice for fish consumption, FDA News Release, ucm397929, June 10, 2014.
  • Fish: What Pregnant Women and Parents Should Know, Draft Updated Advice by FDA and EPA, ucm393070, June 2014.
  • Environmental Protection Agency and Food and Drug Administration Advice About Eating Fish: Availability of Draft Update, FederalRegister, 2014-13584, 06/11/2014.
  • Fish Consumption Advisories, EPA, Fish Advisories, June 11, 2014.

Full Moon Engage Me Social Media Event Frequently Asked Questions

FAQs: what is the #FullMoonEngageMe event about?
What does it cost to play? when does it run?
What do I need to do and where do I need to go?

Join our social media event taking place at each Full Moon and give a boost to your social networking!
  1. What is this about?
    It’s about networking ; it involves buying virtual stocks – on Empire.Kred (and help players improve in wealth) – and allows everyone to connect and super charge their social networking.
  2. What does it COST to play?
    Nothing apart some free time and free eaves.
  3. WHEN does it run?
    Check the full moon calendar dates to get an idea. Each event starts around the announced UTC time (near the full moon day) and usually lasts five days.
  4. What do I need to DO and WHERE do I need to go?
    1. You need to be a member of the EAv Gangstas, a free unrestricted community with open access, no need to apply, everybody is welcome.
    2. and then leave a comment in the pinned post ► dedicated thread/stream ◄ which thereby registers you.
  5. The sign-up post has been locked!
    The pinned post is prepared before the event start – to serve as an announcement – and is locked until the event starts.
    It does unlock during the event. When the event is over, the post is locked again.
  6. Do I have to stick around the full five days?
    Haha! Just come at your best convenience as often as you like 🙂
  7. I have commitments for the whole week and won’t be able to make it!
    We won’t delete the post… Based on that, if you get two free minutes during the event, you can come just to comment in the pinned post… Then you can always come back later when it suits you best to do your buys and connect… The post will be locked but it won’t be deleted, so you’ll always have access to it…
  8. I don’t have much eaves to spend. How can I get extra for FREE?
    There will be some “refuel” missions during the event.
    There are always some free “gift” missions around…
    You might also receive a “moon pie” – see below…
  9. Is there a suggested amount for spending? 
    If you are not “loaded“, spread your eaves so that you can buy a little in ALL participants. Feel free to repeat the operation in the next days if you wish…
  10. What are the Moon Pies?
    You can sometimes find them for sale in Empire.Kred shop during the event.
    Moon pies are to be thrown at someone else.
    Each moon pie received gives you an extra 100,000 eaves cash.
  11. Can you tell who sent you a Moon Pie?
    Yes: go to Empire.Kred “home“.
    Then  click on the [number] next to “Moon Pies sent to you”.
  12. Do I have to reciprocate Moon Pies?
    No. Some players do not spend real cash on Empire.Kred and moon pies are “expensive” for eaves. If you are a moon pie recipient, there are different ways (such as eaves investments, missions, engagement, status updates) to thank the people who sent you a friendly gift.
  13. What is the full moon network for?
    Kred has created a network which displays posts and tweets (via a feed) dedicated to the #FullMoonEngageMe events. You can get some specific content there and also give and get +Kred easily from fellow participants.

More information

  • 2018.12 event N°58 Winter Solstice Moon – EK thread.
  • 2018.11 event N°57 Frost Moon – EK thread.
  • 2018.10 event N°56 Sanguine Moon – EK thread.
  • 2018.09 event N°55 Autumn Equinox Moon – EK thread.
  • 2018.08 event N°54 Red Moon – EK thread.
  • 2018.07 event N°53 Hay Moon – EK thread.
  • 2018.06 event N°52 Hot Moon – EK thread.
  • 2018.05 event N°51 Hare Moon – EK thread.
  • 2018.04 event N°50 Sprouting Grass Moon – EK thread.
  • 2018.03 event N°49 Easter Moon – EK thread.
  • 2018.02 event N°48 Crow Moon – EK thread.
  • 2018.01 event N°47 Super Blue Blood Moon – EK thread.
  • 2018.01 event N°46 New Year Moon – EK thread.
  • 2017.12 event N°45 Cold Moon – EK thread.
  • 2017.11 event N°44 Beaver Moon – EK thread.
  • 2017.10 event N°43 Hunters Moon – EK thread.
  • 2017.09 event N°42 Harvest Moon – EK thread.
  • 2017.08 event N°41 Sturgeon Moon – EK thread.
  • 2017.07 event N°40 Buck Moon – EK thread.
  • 2017.06 event N°39 Strawberry Moon – EK thread.
  • 2017.05 event N°38 Flower Moon – EK thread.
  • 2017.04 event N°37 Pink Moon – EK thread.
  • 2017.03 event N°36 Worm Moon – EK thread.
  • 2017.02 event N°35 Snow Moon – EK thread.
  • 2017.01 event N°34 Wolf Moon – EK thread.
  • 2016.12 event N°33 Long Nights Moon – EK thread.
  • 2016.11 event N°32 Frosty Moon – EK thread.
  • 2016.10 event N°31 Travel Moon – EK thread.
  • 2016.09 event N°30 Barley Moon – EK thread.
  • 2016.08 event N°29 Grain Moon – EK thread.
  • 2016.07 event N°28 Thunder Moon – EK thread.
  • 2016.06 event N°27 Hot Moon – EK thread.
  • 2016.05 event N°26 Milk Moon – EK thread.
  • 2016.04 event N°25 Egg Moon – EK thread.
  • 2016.03 event N°24 Crust Moon – EK thread.
  • 2016.02 event N°23 Hunger Moon – EK thread.
  • 2016.01 event N°22 Old Moon – EK thread.
  • 2015.12 event N°21 Xmas Moon – EK thread.
  • 2015.11 event N°20 Frost Moon – EK thread.
  • 2015.10 event N°19 Blood Moon – EK thread.
  • 2015.09 event N°18 Corn Moon – EK thread.
  • 2015.08 event N°17 Red MoonEAv thread.
  • 2015.07&08 N°16 Blue Moon – EAv thread.
  • 2015.07 event N°15 Hay Moon – EAv thread.
  • 2015.06 event N°14 Rose Moon – EAv thread.
  • 2015.05 event N°13 Flower Moon – EAv thread.
  • 2015.04 event N°12 Pink Moon – EAv thread.
  • 2015.03 event N°11 Worm Moon – EAv thread.
  • 2015.02 event N°10 Snow Moon – EAv thread.
  • 2015.01 event N°9 Wolf Moon – EAv thread.
  • 2014.12 event N°8 Cold Moon – EAv thread.
  • 2014.11 event N°7 Beaver’s Moon – EAv thread.
  • 2014.10 event N°6 Hunter’s Moon – EAv thread.
  • 2014.09 event N°5 Harvest Moon – EAv thread.
  • 2014.08 event N°4 Sturgeon Moon – EAv thread.
  • 2014.07 event N°3 Buck Moon – EAv thread.
  • 2014.06 event N°2 Strawberry Moon – EAv thread.
  • 2014.05 event N°1 Announcement – EAv thread.
  • More about the new social media event – Let’s Connect.
  • More about the new social media event – The Leaders.
  • More about the new social media event – The Reasons.
  • Use the comment section to ask any question about the #FullMoonEngageMe event.
  • You can join – for FREE – Empire.Kred at anytime – before and after any FullMoon EngageMe Social Media Event.

See you soon and have fun 🙂