Single egg transferred IVF babies less likely to be born prematurely, underweight or stillborn

While there has been a considerable increase in assisted reproduction cycles over the past 20 years, this has been accompanied by a significant improvement in health outcomes for these babies

newborn image
While there has been a considerable increase in assisted reproduction cycles over the past 20 years, this has been accompanied by a significant improvement in health outcomes for these babies, particularly for singleton babies.

The health of artificially conceived children has steadily improved in the last 20 years with fewer babies being born prematurely or affected by low birth weight, research has shown. Researchers who analysed data from Nordic countries described the decline in premature and stillbirths as “remarkable“.

This was the main finding of a large cohort study comparing the health of babies born using assisted reproduction technology (ART), such as in vitro fertilisation (IVF), with those conceived naturally over the last 20 years.

Researchers found big improvements over time in a number of areas, including reductions in the number of miscarriages and babies born prematurely or with a low birth weight. All of these can be complications of multiple births (twins, triplets, or sometimes more).

The study looked at ART in Norway, Sweden, Denmark and Finland, and it is unclear whether we could expect to see similar improvements in the UK.

While it is likely we share similar advances in technology and improved protocols with Nordic countries, there may be other important differences as a result of eligibility for treatment.

In some Nordic countries, eligibility for reproductive treatment has been extended to include couples with less severe fertility problems. This may have accounted for some of the improvements seen over the years.

The most recent UK data from 2013 reports the ART multiple birth rate has fallen from 25% in 2008 to 16% in 2013. This would suggest a potentially similar improvement in UK outcomes for ART.

The study carried out at the University Hospital of Copenhagen found implanting one fertilised egg back into the womb reduces the chance of twins or triplets, which increase risks for the unborn babies. Where one egg was transferred babies were less likely to be born prematurely, underweight or stillborn.

Sources and more information

  • Trends in perinatal health after assisted reproduction: a Nordic study from the CoNARTaS group, Oxford Journals, Hum. Reprod. (2015) doi: 10.1093/humrep/deu345, January 20, 2015. Full study PDF.
  • Largest study of babies born after infertility treatment shows significant improvements in health over past 20 years,
    Oxford University Press (OUP), 19 January 2015.
  • IVF babies see health improvement with fewer underweight or stillborn,
    theguardian, 21 January 2015.
  • IVF babies are less likely to be born prematurely or die in infancy than 20 years ago, study reveals, DailyMail, 21 January 2015.
  • Nordic IVF outcomes improving – is the same true for the UK?,
    nhs.uk/news, 21 January 2015.

Meet Russ Kremer: 2013 Growing Green Food Producer

Russ Kremer leads the thriving 52-member Ozark Mountain Pork Cooperative, empowering producers to profitably raise healthy pigs without antibiotics

2013 Growing Green Awards Winner: Food Producer — Known as the “Pope of Pork,” Russ Kremer is a fifth-generation Missouri diversified pork producer and a driving force in the movement for antibiotic-free livestock. After a near-death experience with an antibiotic-resistant bacterial infection Russ contracted from his pigs in 1989, he realized the dangers of conventional production and made immediate changes to his operation. Russ started over to raise pigs the natural, old-fashioned way — free-roaming, pasture-raised and without drugs. Russ leads the thriving 52-member Ozark Mountain Pork Cooperative, empowering producers to profitably raise healthy pigs without antibiotics.

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Toxic chemicals are everywhere

Chances are that your home is polluted with dangerous and sometimes life threatening chemicals…

Watch @DES_Journal diaporama and health posters album on Flickr.

Chances are that your home is polluted with dangerous and sometimes life threatening chemicals…

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Exposure to diethylstilbestrol during sensitive life stages: a legacy of heritable health effects

DES usage review buttress the need for adequate and rigorous research into the use of drugs in pregnancy and ensure that they do more good than harm before being introduced for consumption

DES legacy of heritable health effects ianalysis image
DiEthylStilbestrol usage review buttress the need for adequate and rigorous research into the use of drugs in pregnancy and ensure that they do more good than harm before being introduced for consumption.

Abstract

Diethylstilbestrol (DES) is a potent estrogen mimic that was predominantly used from the 1940s to 1970s in hopes of preventing miscarriage in pregnant women. Decades later, DES is known to enhance breast cancer risk in exposed women, and cause a variety of birth related adverse outcomes in their daughters such as spontaneous abortion, second trimester pregnancy loss, preterm delivery, stillbirth, and neonatal death. Additionally, children exposed to DES in utero suffer from sub/infertility and cancer of reproductive tissues. DES is a pinnacle compound which demonstrates the fetal basis of adult disease. The mechanisms of cancer and endocrine disruption induced by DES are not fully understood. Future studies should focus on common target tissue pathways affected and the health of the DES grandchildren.

Summary

The legacy of the adverse effects that stem from DES administration to pregnant women in the 1950s to 1970s has not completely formed. The male and female offspring of those women have reported significant fertility, cancer, and birth-related outcomes, but the cancer outcomes are not completely understood, with few exceptions (CCA and breast cancer in women over 40 yr old). Information on DES mothers and daughters, in addition to substantial animal data, earned DES a place in the First Annual Report on Carcinogens, a critical review of carcinogenic compounds produced by the National Toxicology Program, in 1980 and was noted by the International Agency for Research on Cancer in their Monographs (IARC 1974). As the male and female offspring of those women age, the overall effect of DES on reproductive cancers will be better understood. Even more important to understand is the potential effect of this endocrine disruptor and carcinogen on the 3rd generation offspring who were not directly exposed, but may be affected in a heritable way through estrogen reprogramming and DNA modification. Further research is needed to indicate the mechanisms of action on the target tissues, so that future pharmaceuticals/environmental estrogen mimics will avoid these pathways, leading to healthier future generations.

Sources and full study
  • Exposure to diethylstilbestrol during sensitive life stages: a legacy of heritable health effects, NCBI PMID: 23897597, Birth Defects Res C Embryo Today.;99(2):134-46. doi: 10.1002/bdrc.21035, 2013 Jun.
  • Full text: PMCID: PMC3817964, NIHMSID: NIHMS520381, doi: 10.1002/bdrc.21035, Nov 5, 2013.
      • INTRODUCTION
      • DES EXPOSURE MAGNITUDE
      • HEALTH EFFECTS
      • Effects in DES Mothers
      • Effects in DES Daughters
      • Effects in DES Sons
      • EFFECTS OF DES IN A 3rd GENERATION
      • GENE CHANGES AND PROPOSED MECHANISMS OF ACTION
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Cervical Cancer – Michelle Whitlock’s Journey

Michelle Whitlock amazing journey included the need for a radical hysterectomy, the birth of a daughter by a surrogate, and the writing of a book chronicling her experiences with cervical cancer

As a young woman, Michelle L. Whitlock was diagnosed with cervical cancer.
Her amazing journey included the need for a radical hysterectomy, the birth of a daughter by a surrogate, and the writing of a book chronicling her experiences with this deadly cancer.

Michelle Whitlock’s book reviews
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What You Need to Know About Cervical Cancer

a @cansa Cervical Cancer infographic

Cervical-Cancer-Infographic
Watch @DES_Journal diaporama and posters album on Flickr.

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Watch @DES_Journal diaporama and health infographics album on  DES Diethylstilbestrol's photostream on Flickr

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Email your photos to des.daughter@gmail.com with a short description and title :-)

New App 99% Effective Form of Natural Birth Control

A natural birth control, clinically proven to be 99.9% safe.
#Beyourself without the interference of hormones.
Green or Red? It’s that simple says @NaturalCyclesNC

Natural Cycles image
A natural birth control, clinically proven to be 99.9% safe. #Beyourself without the interference of hormones. Green or Red? It’s that simple says @NaturalCyclesNC

In many ways, family planning based on keeping track of one’s fertility is about as old-school as it gets. By paying attention to fluctuations in body temperature or cervical fluid, women can track when they’re ovulating and time intercourse so as to increase or decrease their odds of getting pregnant.

Currently, a slew of fertility tracking apps are working to bring family planning into the smartphone era. And now a new app aimed specifically at preventing pregnancy, called Natural Cycles, has hit the market, claiming to identify a woman’s non-fertile days when she is 99 percent safe to have unprotected sex without conceiving. ”

… continue reading The App That Could Be A 99 Percent Effective Form Of Birth Control, huffingtonpost, 01/15/2015.

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Omerta sur la viande: on a recyclé des viandes avariées plusieurs fois

Les graves dérives du secteur viandaire

Pierre Hinard, ancien directeur du service qualité dans une entreprise de transformation de viande en Loire Atlantique, est l’invité de Thomas Sotto à l’occasion de la sortie de son livre Omerta sur la viande – un témoin parle.
Un ouvrage dans lequel il dénonce les graves dérives du secteur…

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The Church of Big Pharma – Pharma religious freedom cartoon

Dan Berger is Cartoonist behind Natural News

big_pharma_church cartoon
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Image via @HealthRanger

The FDA has a long history of attacking and suppressing health freedoms, but did you know the agency might now be threatening religious freedom, too? Under the new CAM Guidelines issued by the FDA, any items used in altering or enhancing the “function” of a living person are subject to regulation and control by the FDA. Items used in religious practices are NOT excluded from these guidelines. ”

Continue reading pharma risk, on The Church of Big Pharma, by Mike Adams, the Health Ranger. April 12, 2007.
Dan Berger is Cartoonist behind Natural News.
Related post: Big Pharma Researcher Pleads Guilty to Fraud, phoenixaquua, 2010/02.

All our posts about Big Pharma and DrugMoney. See more cartoons

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Email your photos to des.daughter@gmail.com with a short description and title :-)

Market Share Liability for DES (Diethylstilbestrol) Injury

A New High Water Mark in Tort Law: Sindell v. Abbott Laboratories

Nebraska university logo image
University of Nebraska College of Law review, 1981

Abstract

In Sindell v. Abbott Laboratories, the California Supreme Court discussed intra-industry liability for adverse effects of drugs and adopted the market share liability theory for DES injuries. Although the majority purported to shift only the burden of proving causation from the plaintiff to the defendants, the effect of its adopting the intra-industry joint liability concept (or, more specifically, the market share doctrine) is to guarantee that the plaintiff will prevail on the causation issue. By departing from traditional tort doctrine and effectively eliminating causation as an issue, “‘[m]arket share’ liability thus represents a new high water mark in tort law.” This Note analyzes Sindell and the various approaches taken to overcome the obstacle of product identification in DES cases. In addition, it examines the legal, social, and economic ramifications of intra-industry joint liability.

Sources
  • Market Share Liability for DES (Diethylstilbestrol) Injury: A New High Water Mark in Tort Law: Sindell v. Abbott Laboratories, 26 Cal. 3d 588, 607 P.2d 924, 163 Cal. Rptr. 132, cert. denied, 101 S. Ct. 285 (1980), Barbara J. Koperski, University of Nebraska College of Law.
  • Full text, Nebraska Law Review, Volume 60 | Issue 2 Article 9, 1981
More DES DiEthylStilbestrol Resources