Cancer Global Killer Worldwide infographic

Infographic showing the leading types of cancer around the world and their death rate

cancer-infographic
Watch @DES_Journal diaporama and health infographics album on Flickr.
Sources and more information

This infographic from the World Health Organization gives an overview of the leading types of cancer around the world and their death rate.

On Flickr®

Will the U.S. be ready on time for their growing population of adults with autism?

1 in 88 can’t wait: the coming tsunami of adults…

Autism definition image
U.S. President Obama recently signed into law the Autism CARES Act, it will give $1.3 billion over five years to fund autism research, services, training and monitoring.

More than 50,000 individuals with autism transition into adulthood each year right now. And autism is on the rise: more than 1.5 million people have the condition in the United States alone, 1 in 88 children aged 8 years have been identified with an autism spectrum disorder in the United States. And because the majority of these people are younger than 22, the country is on the verge of an “autism tsunami” that could leave thousands without the support they need as they become adults, according to Autism Speaks autism advocacy organization.

Read Is the U.S. Prepared for a Growing Population of Adults With Autism?,
by Amir Khan on usnews, Jan. 5, 2015.

More information
  • 72,000-and-Growing: Californiaʼs Autism Epidemic, AutismSociety, October 2014
  • Our Commitment to Supporting Individuals on the Autism Spectrum and their Families, HHS Autism Information, March 27, 2014.
  • Prevalence of Autism Spectrum Disorders — Autism and Developmental Disabilities Monitoring Network, 14 Sites, United States, 2008, CDC, March 2012.
  • Community Report From the Autism and Developmental Disabilities Monitoring, CDC, ADDM Network 2012.

La mort est dans le pré…

Eric Guéret démontre les ravages des pesticides sur la santé des agriculteurs

Documentaire d’Eric Guéret qui démontre les ravages des pesticides sur la santé des agriculteurs en France.

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C’est un film percutant dont personne ne sortira indemne. Mais surtout un film qui dévoile un problème de santé publique autrement plus grave que le pourcentage de cheval roumain dans les lasagnes au bœuf. Un problème de santé publique probablement équivalent à celui de l’amiante, dont les victimes ont enfin été reconnues après plusieurs décennies de combat et de mépris de la part des autorités compétentes, complices de l’industrie. Ce drame, c’est celui vécu par les agriculteurs ou proches d’agriculteurs qui ont été au contact quotidien des pesticides, et qui contractent cancers, maladies neurologiques et autres saloperies susceptibles d’être fatales.

Le réalisateur Eric Guéret est allé à la rencontre de ces gens qui, dans la peine ou la maladie, se battent pour la justice et pour une agriculture plus respectueuse des hommes et de la terre : Caroline Chenet, éleveuse de 45 ans dont le mari a succombé à un lymphome ; Frédéric Ferrand, viticulteur de 41 ans victime d’un cancer de la vessie et de la prostate ; Paul François, contaminé par le « Lasso » de Monsanto et qui mène un combat juridique du pot de terre contre le pot de terre face à la multinationale ; enfin Denis Camuzet, éleveur du Jura qui, bien que paraplégique, voit son avenir dans la conversion en bio de son exploitation.

Comment en est-on arrivé là ? Chacun témoigne à la fois du manque total d’information des fournisseurs de produits, qui s’abstiennent bien d’alerter sur leur dangerosité, de l’inconscience durable des agriculteurs comme dans cette scène où les parents de Frédéric, également vignerons, parlent de l’aspersion des produits alors qu’ils étaient encore dans les vignes : « ça faisait l’effet d’une douche fraiche en plein été ». Et puis il y a dans toutes les bouches la reconnaissance de ce foutu sens du silence qui règne chez les paysans. Le paysan est solidaire de son voisin pour les travaux, mais n’évoque jamais ni les problèmes d’argent, ni les problèmes personnels, ni même ceux de santé, fierté oblige. Et dénoncer les pesticides est souvent perçu comme une forme de trahison face à quelque chose qui a permis à chacun d’augmenter ses rendements et de mieux vivre matériellement. Mais voilà, la maladie est là et avec elle la prise de conscience d’une énorme duperie criminelle. Et la prise de conscience est telle que certains avouent ne plus donner à leur famille la production de leur récolte, se limitant à ce qui sort du potager privé cultivé en bio. Désormais ces paysans interviewés ne se taisent plus et mènent un combat parfois désespéré : combat auprès de la Mutuelle Sociale Agricole pour faire reconnaître son cancer comme maladie professionnelle, combat contre les scientifiques stipendiés par l’industrie, combat pour changer de pratiques, un défi pour ceux que l’agro-industrie a coupés de tous leurs savoirs traditionnels. Et malgré le tragique de la situation, grâce à l’obstiné Denis Camuzet, l’éleveur qui veut devenir bio, ou à la victoire juridique de Paul François, ce film reste plein d’espoir dans la lutte.

Regardez cette liste de produits chimiques et pesticides sur notre chaîne YouTube.

Opération Mains Propres sur la Santé

Cartoon de Jean-Louis Savignac, merci @Formindep @MicheleRivasi

Mains-Propres
@DES_Journal soutient Michèle Rivasi et le Formindep qui demandent une réforme totale de la filière du médicament.

L’appel “Opération mains propres sur la santé” dénonce à juste titre la surconsommation de médicaments et les prix prohibitifs pratiqués. De telles anomalies sont le fruit des multiples conflits d’intérêts qui caractérisent le circuit du médicament en France mais aussi du refus de l’Etat de lutter contre la stratégie d’influence des laboratoires, notamment auprès des professionnels de santé.

Sources et en savoir plus

Sur Flickr®

Pregnancy Apps: where is the Reset Option for Miscarriages?

A plethora of pregnancy apps promise answers and support during this life-changing time…

I was preparing a post overview about pregnancy apps, when I came across a review that I found of circumstance for DES Daughters and DES Grand Daughters:

Pregnant_woman_cell_phone image
A plethora of pregnancy apps promise answers and support during this life-changing time…
Okay, sounds great, but where is the reset option for miscarriages?

It was an awesome app while I was pregnant but at 10 weeks 3 days at our first US we found out I am miscarrying. This is very emotionally painful for anyone who has to go through this. This app just made it worse, there is no “report a miscarriage” button or even a reset button. When I tried to erase this pregnancy the app even pops up a message saying “you must have at least one baby entered in the app” this message alone made me tear up and say “well thanks, ya I know I don’t have a baby anymore thanks a lot webmd” now I’ll just have to wait for the continued email update of my pregnancy and opt out that way, causing more pain. please make some changes to the app to make this an easier transition for moms who experience miscarriages. Thanks

Many DES-exposed women have experienced miscarriages, and even recurrent miscarriages… Some of us want to have kids but are struggling or unable to…
Sadly for many DES daughters having their own children is not possible!
Read more about DES pregnancy risks and studies about DES and pregnancy.

Blog Post Sources

Detox the Box – Video Spoof of Justin Timberlake’s “Dick in a Box” on SNL

Toxic chemicals don’t belong in feminine products. Period

Toxic chemicals don’t belong in feminine products. Period. Take Action => Tell Always to detox the box : remove harmful chemicals and list all ingredients. Clearly, American women are ready for a new conversation about personal care, and they deserve to know what ingredients are in their most intimate products says Women’s Voices for the Earth.

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Hormonal Chaos

Scientific and Social Origins of the Environmental Endocrine Hypothesis

Hormonal-Chaos book cover image
A detailed description by a scientific and policy insider of an emerging theory and the response of the scientific and legislative communities.

The broader environmental endocrine hypothesis (EEH), is the subject of Hormonal Chaos, by Sheldon Krimsky, 2000. The premise behind the EEH is that chemicals mimicking endocrine hormones can bind to receptors and thus can cause health problems in humans as well as other animals. Krimsky shows how this hypothesis first developed within the scientific community, in large part as a result of the persistence and insight of Theo Colborn. While working for the nonprofit Conservation Foundation in the 1980s, Colborn formulated the EEH, linking together evidence from several disparate sources: deleterious effects on wildlife exposed to pesticides, defects in babies whose mothers took the estrogen substitute diethylstilbestrol (DES) and controversial claims that human sperm is declining in quantity and quality.

Sources and book reviews

  • Hormonal Chaos: The Scientific and Social Origin of the Environmental Endocrine Hypothesis, NCBI PMC1118410, British Medical Journal; 321(7259):516, BMJ 2000 Aug 19.
  • The Case of the Deformed Frogs, americanscientist, July-August 2000.
  • Amazon customer reviews.
On Flickr®
More DES DiEthylStilbestrol Resources

Differential Effects of BPA and DES on Human, Rat and Mouse Fetal Leydig Cell Function

EDCs have been incriminated in the current increase of male reproductive alterations

mouse-lab-rat image
This 2012 study shows for the first time that concentrations of BPA as low as 10−8 M are sufficient to reduce fetal testis endocrine activity in humans.

2012 Study Abstract

Endocrine disruptors (ED) have been incriminated in the current increase of male reproductive alterations. Bisphenol A  (BPA) is a widely used weak estrogenic environmental ED and it is debated whether BPA concentrations within the average internal exposure are toxic. In the present study we investigated the effects of 10−12 to 10−5 M BPA concentrations on fetal Leydig cell function, as fetal life is a critical period of sensitivity to ED effects on male reproductive function. To this aim, fetal testes from human at 6.5–10.5 gestational weeks (GW) or from rat and mouse at a comparable critical period of development (14.5 days post-coitum (dpc) for rat and 12.5 dpc for mouse) were explanted and cultured using our validated organotypic culture system in the presence or absence of BPA for 1–3 days. BPA concentrations as low as 10−8 M reduced testosterone secretion by human testes from day 1 of culture onwards, but not by mouse and rat testes where concentrations equal to 10−5 M BPA were required. Similarly, 10−8 M BPA reduced INSL3 mRNA levels only in human cultured testes. On the contrary, 10−5 and 10−6 M diethylstilbestrol (DES), a classical estrogenic compound, affected testosterone secretion only in rat and mouse testis cultures, but not in human testis cultures. Lastly, contrarily to the DES effect, the negative effect of BPA on testosterone produced by the mouse fetal testis was maintained after invalidation of estrogen receptor α (ERα). In conclusion, these results evidenced i) a deleterious effect of BPA on fetal Leydig cells function in human for concentrations from 10−8 M upwards, ii) species-specific differences raising concerns about extrapolation of data from rodent studies to human risk assessment, iii) a specific signaling pathway for BPA which differs from the DES one and which does not involve ERα.

2012 Study Conclusions

We show here for the first time that concentrations of BPA as low as 10−8 M are sufficient to reduce fetal testis endocrine activity in humans. The mechanism of action of BPA will need further investigation, but it is likely to involve non-classical estrogen receptors.

The negative effect of BPA on testosterone production and Insl 3 expression during fetal life observed here during the “masculinization programming window”, may have several consequences as it can impair the masculinization of internal and external genitalia [4], [7], [13]. Our present results should encourage prospective epidemiological studies to investigate the possible association between environmental exposure to BPA during pregnancy and anogenital distance at birth. Furthermore, BPA-induced reduction of fetal testosterone production may have long-term consequences. Although brain masculinization and the onset of male-specific sexual behaviors start during the second half of pregnancy, we can’t exclude that BPA-induced reduction of fetal testosterone production during the first trimester of pregnancy may influence these parameters [70]. It may also affect the germ cell lineage since androgens control gonocyte development [71]. Thus, it will be relevant to study the effect of BPA on gonocytes since alterations of the germ cell lineage may result in testicular cancer or in reduced sperm production [3], [4] and may also explain the recently reported multigenerational effects of BPA [72].

Finally, our findings challenge the widespread use of rodent models to assess the toxic effects of EDs and highlight the need for setting up specific tools to study reprotoxicity in humans.

Sources and Full Study
  • Differential Effects of Bisphenol A and Diethylstilbestrol on Human, Rat and Mouse Fetal Leydig Cell Function, PLOS one, DOI: 10.1371/journal.pone.0051579, December 17, 2012.
More DES DiEthylStilbestrol Resources

La France est-elle malade de ses médicaments?

Réformer en profondeur la politique du médicament en France,
l’interview Mediapart de Michele Rivasi

Un appel à dix millions d’euros… Il est lancé par la député européenne Michèle Rivasi, membre d’Europe Ecologie. Elle considère, chiffres et noms à l’appui, que la filière du médicament est gangrenée en France par les conflits d’intérêt entre pouvoir politique et laboratoires pharmaceutiques. Vidéos publiée 14 Jan 2015 par Mediapart.

Plus d’information

Medical Condition In Case of Emergency Card

I.C.E. cards gives first responders key information on critical health issues

Those ICEcards have a fully writable reverse allows details to be filled in on who should be contacted in the event of an accident or incident.

Medical-Condition-I.C.E
Watch @DES_Journal diaporama and health posters album on Flickr.

Sources and more information

I.C.E. Cards give first responders key information on critical health issues; such as medication use, allergies or pre-existing conditions. It is easily identifiable and instantly to hand unlike carrying your details in a mobile phone, which may be locked or difficult to operate.

On Flickr®