Stop the superbugs linked to antibiotics daily use in livestock

Tell the meat industry to clean up its act

0% of all antibiotics are used on factory farm animals which eventually leads to antibiotic resistant super-bugs. We can fix this problem. Support meat without drugs and help stop the superbugs.

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La vérité sur vos médicaments

32 médecins tentent de rétablir “la vérité”

verite-sur-medicaments cover image
Nous avons décidé d’écrire ce livre pour dire la vérité sur les médicaments. “

Une analyse indépendante, sans parti pris, sur les médicaments en France, leur développement, leur évaluation, leur bon et leur mauvais usage.

  • Les malades et leur entourage ne savent plus à quel saint se vouer. Qui croire ?
  • Faut-il se méfier des médicaments ?
  • Peut-on faire confiance à son médecin ? à son pharmacien ?
  • Les responsables publics contrôlent-ils réellement l’industrie pharmaceutique ?
  • Les experts sont-ils tous « achetés » ou « vendus » ?
  • Consommons-nous trop de médicaments ? Comment s y retrouver ?

Résultat de l’expérience croisée de 32 spécialistes et de l’analyse d’essais cliniques d’envergure mondiale, le livre La Vérité sur vos médicaments apporte des réponses scientifiquement validées.

Alliés indispensables de la médecine et moteurs de son progrès, les médicaments sont au coeur du système de santé. Ils ont permis le recul des maladies contagieuses, opéré de grands bouleversements en cancérologie, des quasi miracles en cardiologie, en rhumatologie, en gastro-entérologie… Ils ont rendu possibles les greffes d organes, de tissus ou de cellules.

Si l’on guérit de plus en plus de nos jours et si l’on soigne de mieux en mieux les maladies chroniques, le diabète ou l’asthme, ce n est jamais sans l’aide des médicaments. Telle est la vérité qu il nous a paru urgent de rappeler. Sans ignorer que le progrès a son revers : les abus, les falsifications, les scandales.

Chaque auteur a déclaré ses liens d’intérêts, défendu ses thèses en toute indépendance et, lorsqu il y a lieu, les désaccords entre spécialistes ont été signalés.
Les droits d’auteur issus de ce livre sont intégralement versés à la Fondation pour la recherche médicale.

En savoir plus

  • 32 médecins dévoilent “La vérité sur vos médicaments”, sciencesetavenir, 25-03-2015.
  • Médicaments : 32 experts tentent de rétablir “la vérité”, pourquoidocteur, 25 Mars 2015.
  • “La Vérité sur vos médicaments”: un livre pour mieux comprendre, notretemps, 24 mars 2015.
  • Médicaments : Odile Jacob publie un livre « vérité », le moniteur des pharmacies, 24/03/2015.
  • Vérité sur les médicaments : livre-évènement chez Odile Jacob, jeanyvesnau, 2015/03/24.
Sur Flickr®

 

Effect of in utero exposure to DES on lumbar and femoral bone, articular cartilage, intervertebral disc

DES significantly affected the musculoskeletal system of adult mice

lab-mouse image
DES significantly affected the musculoskeletal system of adult mice. Results suggest that environmental estrogen contaminants can have a detrimental effect on the developmental lumbar bone growth and mineralization in mice. Further studies measuring the impact of environmental estrogen mimics, such as bisphenol A, are then warranted.

2012 Study Abstract

INTRODUCTION:
Developmental exposure to estrogens has been shown to affect the musculoskeletal system. Furthermore, recent studies have shown that environmental exposure to estrogen-like compounds is much higher than originally anticipated. The aim of this study was to determine the effects of diethylstilbestrol (DES), a well-known estrogen agonist, on articular cartilage, intervertebral disc (IVD), and bone phenotype.

METHODS:
C57Bl/6 pregnant mice were dosed orally with vehicle (peanut oil) or 0.1, 1.0, and 10 μg/kg/day of DES on gestational days 11 to 14. Male and female pups were allowed to mature without further treatment until 3 months of age, when swim and sedentary groups were formed. After euthanasia, bone mineral density (BMD), bone mineral content (BMC), bone area (BA), and trabecular bone area (TBA) of the lumbar vertebrae and femur were measured by using a PIXImus Bone Densitometer System. Intervertebral disc proteoglycan was measured with the DMMB assay. Histologic analysis of proteoglycan for IVD and articular cartilage was performed with safranin O staining, and degeneration parameters were scored.

RESULTS:
The lumbar BMC was significantly increased in female swimmers at both the highest and lowest dose of DES, whereas the femoral BMC was increased only at the highest. The males, conversely, showed a decreased BMC at the highest dose of DES for both lumbar and femoral bone. The female swim group had an increased BA at the highest dose of DES, whereas the male counterpart showed a decreased BA for femoral bone. The TBA showed a similar pattern. Proteoglycan analysis of lumbar IVDs showed a decrease at the lowest doses but a significant increase at the highest doses for both males and females. Histologic examination showed morphologic changes of the IVD and articular cartilage for all doses of DES.

CONCLUSIONS:
DES significantly affected the musculoskeletal system of adult mice. Results suggest that environmental estrogen contaminants can have a detrimental effect on the developmental lumbar bone growth and mineralization in mice. Further studies measuring the impact of environmental estrogen mimics, such as bisphenol A, are then warranted.

Sources and Full Study
  • Effect of in utero exposure to diethylstilbestrol on lumbar and femoral bone, articular cartilage, and the intervertebral disc in male and female adult mice progeny with and without swimming exercise, NCBI PMID: 22269139, 2012 Jan 23;14(1):R17. doi: 10.1186/ar3696.
  • Full study, PMC3392807, 2012;14(1):R17. doi:10.1186/ar3696.
More DES DiEthylStilbestrol Resources

Creating a meaningful and fulfilling life without children

Jody Day talks about women and childlessness

WOW Bites ran over the course of the Women Of The World festival weekend – little talks with inspiring ideas and everything in between.

In this Bite, Jody Day, voice of childless-by-circumstance women, talks about creating a meaningful and fulfilling life without children.

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What’s hiding in those Pads?

Toxic chemicals do not belong in feminine products. Period

What's-hiding-in-those-Pads
Watch @DES_Journal diaporama and health posters album on Flickr.

Always: detox the box! Toxic chemicals don’t belong in pads. Period.
Women’s Voices for the Earth November 2013 Chem Fatale report found toxic chemicals commonly used in feminine care products like pads and tampons.

On Flickr®

Why Brazil has a big appetite for risky pesticides

Brazil passed the United States as the largest buyer of pesticides

Brazil became an enticing market for pesticides banned or phased out in richer nations because of health or environmental risks.

The farmers of Brazil have become the world’s top exporters of sugar, orange juice, coffee, beef, poultry and soybeans. They’ve also earned a more dubious distinction: In 2012, Brazil passed the United States as the largest buyer of pesticides.

In this farming superpower, agricultural chemicals – including paraquat – face lax regulation. And in the rural northeast, rampant use has led to sickness and violence. ”

Continue reading Why Brazil has a big appetite for risky pesticides,
by Paulo Prada on Reuters. April 2, 2015.

Groups petition federal agency to ban products containing certain flame-retardants

Some of the highest levels of flame-retardants are found in children…

Content on this post is produced by Brian Bienkowski on Environmental Health News

Global-Orphan-Project image
A diverse group of organizations petitions the Consumer Product Safety Commission to ban products containing a class of flame-retardants linked to cancer, hormone disruption and reproductive problems.
Image of kids unloading their new mattresses via The Global Orphan Project.

A group of firefighters, scientists, and health and consumer advocates are petitioning federal authorities to ban children’s products, furniture, mattresses and electronic casings if they contain a class of flame-retardants.

The petition, announced March 31, 2015 and put together by the Green Science Policy Institute and Earthjustice, calls on the Consumer Product Safety Commission to ban these products if they contain organohalogens flame-retardants, a class of chemicals that have been linked to cancer, hormone disruption, and reproductive, developmental and immune system problems, according to the petitioners.

By targeting an entire class of compounds, rather than a single chemical, the petition is a new approach to tackling the seemingly intractable problem of keeping up with harmful chemicals in our environment, said Arlene Blum, executive director of the Green Science Policy Institute.

There are more than 80,000 chemicals registered in the United States, most of which haven’t been fully studied for potential health impacts. The National Toxicology Program estimates 2,000 new chemicals are introduced every year.

Some flame-retardants, such as polybrominated diphenyl ethers (PBDEs), have been largely banned or voluntarily phased out by manufacturers because they’re persistent in the environment and toxic. But the replacements often have similar properties to the banned compounds, something Blum referred to as “toxic whack-a-mole.”

Moving from a harmful substance to its chemical cousin,” she said.

Organohalogen flame-retardants are added to products such as mattresses, baby strollers, changing pads, the casings of computers and TVs, and building insulation to keep them from catching fire.

But because some of these compounds do not stay in products – but can migrate into dust – almost all people have these compounds in their bodies. Some of the highest levels of flame-retardants are found in children, mostly because of their hand-to-mouth habits.

U.S. National Institute of Environmental Health Sciences director Linda Birnbaum, a toxicologist who specializes in the health effects of environmental contaminants, said she understands the petition but thinks it may be a bit too ambitious.

Just banning things because they have a halogen atom in them could be problematic,” Birnbaum said. “There may be sub-classes that we could look at, or certain chemical structures that are known to be problematic, but I can’t say that banning an entire class is the way to go.”

Numerous animal studies have shown the compounds to impact development and reproduction and disrupt the endocrine system.

Several organohalogen flame-retardants, or their by-products, are banned by the Stockholm Convention on Persistent Organic Pollutants, a global treaty of 150 countries. The first 12 compounds the Convention banned were organohalogen pesticides, such as DDT.

The Consumer Product Safety Commission doesn’t have a set timeline to deal with the petition, said Eve Gartner, a staff attorney at EarthJustice, who is working on this case.

If it meets criteria as a legit petition, it could possibly be open to public comment, as some petitions in the past have, Gartner said. Most petitions sent to the Commission have not dealt with chemicals, she said.

Clearly they [the Commision] have authority over toxic chemicals,” Gartner said, referring to the Federal Hazardous Substances Act. “They just haven’t used it much.”

A major issue with flame-retardants is whether they’re effective and necessary in products. The chemicals became widely used in the 1970s after a California law required furniture to be more resistant to flames.

However, an investigation three years ago by the Chicago Tribune found that since the California law, deceptive campaigns have promoted flame-retardant use and the chemicals don’t always work as promised. In 2013, California relaxed the 1970s law and now requires furniture made with flame-retardants to be labeled as such.

But that doesn’t necessarily mean that all flame-retardants aren’t needed, Birnbaum said.

Maybe we don’t need them in all of the mattresses, furniture, but I think we might need them in electronics,” she said. “Have electronics changed enough that they are no longer subject to sparking?”

The petition has a diverse backing and includes the American Academy of Pediatrics, the National Hispanic Medical Association, the International Association of Fire Fighters, the Learning Disabilities Association of America, Consumers Union, Consumer Federation of America, the League of United Latin American Citizens, Worksafe and Dr. Philip J. Landrigan of the Mount Sinai School of Medicine.

The children’s health organizations cited research that showed women with higher levels of flame retardants in their blood had babies with lower birth weights and, years later, the children had lower IQs.

Harold Schaitberger, general president of the International Association of Fire Fighters, said in a statement that flame-retardants create “a serious health risk for fire fighters.”

A 2013 study found elevated levels of flame-retardants and harmful byproducts in twelve San Francisco firefighters’ blood. Researchers suspect such exposure might be behind the elevated rates of cancer that firefighters suffer from, as reported by the National Institute of Occupational Safety and Health last year.

While the petition seeks to address new products containing these chemicals, there’s also the “tens of millions of toxic couches and other products” that already contain them, Blum said.

This petition and process can start helping people change about how they think about chemicals,” she said. “One way we’ll get ahead is to think about classes when we’re talking about harmful compounds in everyday products.”

Sources and more information

  • Pediatricians, Scientists, Firefighters Petition Government to Ban Products With Harmful Flame Retardants, GREEN SCIENCE POLICY INSTITUTE.
  • Petition for Rulemaking, filed with the Consumer Product Safety Commission, earthjustice, March 31, 2015.
  • HEALTH, FIREFIGHTER, CONSUMER AND SCIENCE GROUPS SEEK BAN ON HOUSEHOLD PRODUCTS WITH TOXIC CHEMICAL FLAME RETARDANTS, earthjustice, March 31, 2015.
  • Groups petition federal agency to ban products containing certain flame-retardants, Environmental Health News, March 31, 2015.

Consumers worried about GMOs and pesticides

People are hungry for more information about what they put into their bodies

A recent survey shows people are hungry for more information about what they put into their bodies.

Watch @DES_Journal diaporama and health infographics album on Flickr

Image sourcesConsumer Attitudes and Preferences About Food Safety, Shopping Options, Allergies and Diets on healthline.

On Flickr®

World Autism Awareness Day video

Dancers help raise awareness of autism

On World Autism Awareness Day, Tuesday 02 April 2013, Autism Queensland and supporters turned the Queen Street Mall in Brisbane blue to raise awareness about people living with Autism, their families, carers and teachers.

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  • Video published on 7 Apr 2013 by Autism Queensland.
  • The event marked the start of Autism Awareness Month and the formal kick-off of Autism Queensland’s fundraising and awareness campaign Go Blue for Autism. Dancers in blue morph suits captured the attention of curious onlookers and help raise awareness of autism — a condition that research shows affects one in 100 Australian children.
  • World Autism Awareness Day, autismspeaks.
  • On World Autism Awareness Day, Thoughts On Parenting A Son With Autismhuffingtonpost. 04/02/2015.

People’s skin covered with the chemical residues from shampoos and beauty products

Scientists Map The Chemical Residues On Skin

Scientists who’ve created the first 3-D map of a person’s skin say people are covered with the chemical residues from shampoos, beauty products and even clothing.
Scientists who’ve created the first 3-D map of a person’s skin say people are covered with the chemical residues from shampoos, beauty products and even clothing. Image by andercismo.

Significance
The paper describes the implementation of an approach to study the chemical makeup of human skin surface and correlate it to the microbes that live in the skin. We provide the translation of molecular information in high-spatial resolution 3D to understand the body distribution of skin molecules and bacteria. In addition, we use integrative analysis to interpret, at a molecular level, the large scale of data obtained from human skin samples. Correlations between molecules and microbes can be obtained to further gain insights into the chemical milieu in which these different microbial communities live.

Abstract
The human skin is an organ with a surface area of 1.5–2 m2 that provides our interface with the environment. The molecular composition of this organ is derived from host cells, microbiota, and external molecules. The chemical makeup of the skin surface is largely undefined. Here we advance the technologies needed to explore the topographical distribution of skin molecules, using 3D mapping of mass spectrometry data and microbial 16S rRNA amplicon sequences. Our 3D maps reveal that the molecular composition of skin has diverse distributions and that the composition is defined not only by skin cells and microbes but also by our daily routines, including the application of hygiene products. The technological development of these maps lays a foundation for studying the spatial relationships of human skin with hygiene, the microbiota, and environment, with potential for developing predictive models of skin phenotypes tailored to individual health.

Sources and more information