Urogenital tract abnormalities in sons of women treated with diethylstilbestrol

Urogenital abnormalities in men exposed to DES in utero, 1976

image of son-in-arms
In this 1976 survey, a large proportion of DES- exposed boys had experienced problems in passing urine and abnormalities of the penile urethra. Can’t let go image by Paolo Marconi.

1976 Study Abstract

Since in utero exposure to Diethylstilbestrol (DES) is known to cause abnormalities of the female genital tract later in life, exposed male offspring were located, surveyed by mail, and compared with unexposed male offspring from the same period and medical practices.

The exposed and unexposed respondents appeared comparable and did not differ in their response to most medical questions. However, a larger proportion of exposed than of unexposed boys had experienced problems in passing urine (12.9% vs. 1.8%, P = .0003) and abnormalities of the penile urethra (4.4% vs. 0%; P = .017).

Sources and more information

  • Urogenital tract abnormalities in sons of women treated with diethylstilbestrol, Pediatrics. NCBI PMID: 972792, 1976 Oct;58(4):505-7.
  • Urogenital abnormalities in men exposed to diethylstilbestrol in utero: a cohort study, NCBI, PMID: 19689815, 2009 Aug 18;8:37. doi: 10.1186/1476-069X-8-37. Full text PMC2739506.
More DES DiEthylStilbestrol Resources

Author: DES Daughter

Activist, blogger and social media addict committed to shedding light on a global health scandal and dedicated to raise DES awareness.

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