Age at menarche among diethylstilbestrol granddaughters

Age at menarche for DES granddaughters seemed to be unaffected by mother’s prenatal DES exposure

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In this 1995 study, age at menarche for DES granddaughters seemed to be unaffected by mother’s prenatal diethylstilbestrol exposure. However the 2011 study showed DES-exposed girls were somewhat more likely to have begun menstruating at age 10 or younger.

1995 Study Abstract

American journal of obstetrics and gynecology, NCBI PMID: 7573253, 1995 Sep.

We interviewed 542 women whose mothers were in a randomized trial of diethylstilbestrol. Effects of diethylstilbestrol on the third generation were explored by ascertaining age at menarche for the women’s daughters. A total of 123 daughters were > or = 10 years old (52 exposed and 71 unexposed). Age at menarche was unaffected by mother’s prenatal diethylstilbestrol exposure.

Sources and more information
More DES DiEthylStilbestrol Resources

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