How we expect researchers to make all their data available
The movement to make data from clinical trials widely accessible has achieved enormous success, and it is now time for medical journals to play their part. From 1 July The BMJ will extend its requirements for data sharing to apply to all submitted clinical trials, not just those that test drugs or devices.
The BMJ’s Elizabeth Loder explains what this means for authors, and how we expect researchers to make their data available.
Doctors are being warned not to encourage young women to freeze their eggs as a way to avoid “future regret,” says a just-published article in the Canadian Medical Association Journal that argues egg freezing risks perpetuating expectations that being a mother is central to being a woman. Press Play> to listen to the recording.
Sources and more information
Social egg freezing: risk, benefits and other considerations, cmaj, April 13, 2015.
Family doctors important in advising young women on egg freezing for future fertility, eurekalert, 13-APR-2015.
Doctors warned not to encourage young women to freeze their eggs in new medical journal article, nationalpost, April 14, 2015.
Egg freezing not a fertility panacea, Metro Canada, April 14, 2015.
In his recent investigation about the FDA, fraud and misconduct in scientific studies of medicine, Charles Seife – Journalist, author, NYU professor – and his students revealed that the FDA routinely fails to report evidence of fraud or misconduct when it inspects the way researchers conduct clinical trials, leaving the public unaware of which research is credible and which is not. Press Play> to listen to the recording.
Research Misconduct Identified by the US Food and Drug AdministrationOut of Sight, Out of Mind, Out of the Peer-Reviewed Literature, JAMA Intern Med. Published online, doi:10.1001/jamainternmed.2014.7774, February 09, 2015.
The FDA doesn’t tell you when it finds scientific fraud, theverge, February 9, 2015.
FDA fails to report fraud in clinical trials – study, Reuters, February 10, 2015.
Medical Fraud Missing From Public Record, sciencefriday, FEB. 13, 2015.
La vie de Sylvie a été ravagée par le Distilbène, cette hormone de synthèse prescrite à sa mère et supposée éviter les fausses couches.
Deux grossesses pathologiques, un fils polyhandicapé à la vie dévastée, une carrière internationale stoppée, une vie de couple bouleversée, un cancer de l’utérus, un quotidien difficile à gérer… Sylvie publie son livre “Distilbène, Mon Fils n’aura Jamais son Bac” et dénonce le laboratoire UCB Pharma.
How withholding clinical trials degrades the evidence base
Science & the City interviews Dr Ben Goldacre – author of Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients – who discusses the pervasive bias in reporting clinical trials of medications.
Dr Ben Goldacre calls for all trials to be registered and for all trial results to be reported. Otherwise, he says, doctors, researchers, and patients are prevented from making discerning decisions about treatments and the field of evidence-based medicine is pointlessly hobbled.
Alok Jha, Science correspondent at the Guardian and BBC TV presenter, speaks at length with Campaigner, Writer, Dr Ben Goldacre about his investigation into the pharmaceuticals industry and his book Bad Pharma.