BPA Exposure linked to 80pc increased Risk of Miscarriage for pregnant Women

Conjugated Bisphenol A (BPA) in maternal serum in relation to miscarriage risk

Canned foods, plastic containers and receipts all increase risk of miscarriage for pregnant women, scientists warn
One of the first studies looking at the evidence in humans shows worrying link between chemical BPA and infertility.

A new research, on a group of women who had a history of miscarriages and difficulties conceiving, suggests that high levels of Bisphenol-A (BPA) – chemical found in many plastics and canned food – might raise the risk of miscarriage up to 80 percent greater – in women prone to that problem or having trouble getting pregnant.

Study Abstract

Objective
To examine the relationship between the maternal serum bisphenol A (BPA) concentration at the time of the missed menstrual cycle and miscarriage risk.

Design
Retrospective cohort of prospectively collected serum samples.

Setting
Academic fertility center.

Patient(s)
Women presenting for early pregnancy monitoring with singleton pregnancies.

Intervention(s)
Stored serum samples from 4 to 5 weeks’ gestation analyzed for conjugated serum BPA concentrations.

Main Outcome Measure(s)
Live birth, miscarriage, and chromosome content of miscarriage.

Result(s)
With the 115 women included in the study, there were 47 live births and 68 clinical miscarriages (46 aneuploid and 22 euploid). Median conjugated BPA concentrations were higher in the women who had miscarriages than in those who had live births (0.101 vs. 0.075 ng/mL). Women with the highest quartile of conjugated BPA had an increased relative risk of miscarriage (1.83; 95% CI, 1.14–2.96) compared with the women in the lowest quartile. We found a similar increase risk for both euploid and aneuploid miscarriages.

Conclusion(s)
Maternal conjugated BPA was associated with a higher risk of aneuploid and euploid miscarriage in this cohort. The impact of reducing individual exposure on future pregnancy outcomes deserves further study.

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4 thoughts on “BPA Exposure linked to 80pc increased Risk of Miscarriage for pregnant Women”

  2. Getting pregnant is never as easy as shown in the movies.Although some women do conceive very easily, but owing to our fast paced and hectic lifestyle in today’s age, not everyone is that fortunate. On an average, it takes about 5-6 months of trying to actually conceive while for a little older women in their thirties, it might take more time.
    Everett

    Reply

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