Dr. Jamie DeWitt describes scenarios where endocrine disrupting chemicals can alter brain development by changing signals to the immune cells that can mediate development of sex specificity in the brain.
Building on the January 8, 2014 teleconference featuring Dr. Rodney Dietert on how the developing immune system is a target for endocrine disrupting chemicals, Dr. Jamie DeWitt discussed how certain cells of the immune system may mediate endocrine signals to direct aspects of brain development. She also described scenarios where endocrine disrupting chemicals can alter brain development by changing signals to the immune cells that can mediate development of sex specificity in the brain.
Sources:
- Endocrine Disruption and Immune Dysfunction, healthandenvironment.org, Feb 19, 2014.
- SlideShare presentation, Jan 8, 2014.
- DES Daughter Network on SlideShare.
Additional resources of interest:
- Suppression of Humoral Immunity by Perfluorooctanoic Acid is Independent of Elevated Serum Corticosterone Concentration in Mice – PDF
- Current Status of Developmental Immunotoxicity: Early-Life Patterns and Testing – PDF
- Breaking Patterns of Environmentally Influenced Disease for Health Risk Reduction: Immune Perspectives – PDF
- Bisphenol A: Developmental Toxicity from Early Prenatal Exposure – PDF