Female fertility prognosis and diethylstilbestrol – high-risk pregnancies and successful childbearing

Adapted psychological and medical care can lead to successful childbearing

Las-manos-del-destino
In spite of their difficult past reproductive history 4 young DES-women conceived successfully with adapted psychological and medical care in 1998 in France. Las manos del destino.

1998 Study Abstract

Diethylstilbestrol (DES) exposure in utero in females is a cause of clear-cell adenocarcinoma of the cervix and of several anatomical and functional disorders of the genital tract. DES exposure must be evoked whenever counselling women for reproductive disorders.

In France around 80,000 women have had in utero DES exposure. The cases of 4 young women who consulted our Reproduction Center for reproductive disorders illustrate the usual difficulties faced by these patients.

In spite of their difficult past reproductive history (uterine malformations, repeated miscarriages, ectopic pregnancies) and low fertility rate, all four women conceived successfully, either after spontaneous or induced ovulation. We stress the need for adapted psychological and medical care which can lead to successful childbearing in the vast majority of these high-risk patients.

Sources and more information
  • Female fertility prognosis and diethylstilbestrol. Personal data and review of the literature, Journal de gynécologie, obstétrique et biologie de la reproduction, NCBI PMID: 9648005, 1998 Apr.
More DES DiEthylStilbestrol Resources

Have your say ! Share your views