New Gardasil 9 vaccine, now targeting nine strains of human papillomavirus HPV

The new HPV vaccine is said to be more effective

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Merck has been working to discover and develop vaccines for more than a century.
Their new 9vHPV vaccine prevented infection and disease related to HPV-31, 33, 45, 52, and 58 in a susceptible population and generated an antibody response to HPV-6, 11, 16, and 18.

A new version of the regular Gardasil vaccine – called Gardasil 9 – that fights nine strains of human papillomavirus offers greater cancer protection for women than the earlier one – which the NHS offers to all girls aged 12 to 13 – that targets only four.

The results of Gardasil 9 clinical trial, which was funded by Merck, are published in the New England Journal of Medicine.

We still need to remember that the vaccine prevent infections due to HPV only ; researchers will have to track the vaccinated women for many more years to see whether the two vaccines ultimately prevents more cancers…

The new vaccine already caused more side effects, from mild to severe…

Sources and more information

  • A 9-Valent HPV Vaccine against Infection and Intraepithelial Neoplasia in Women, The New England Journal of Medicine 2015; 372:711-723 February 19, 2015DOI: 10.1056/NEJMoa1405044 Supported by Merck.
  • Vaccine that targets 9 strains of HPV boosts cancer protection, study says, latimes, February 18, 2015.
  • FDA approves Gardasil 9 for prevention of certain cancers caused by five additional types of HPV, FDA News Release, December 10, 2014.


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