The broader environmental endocrine hypothesis (EEH), is the subject of Hormonal Chaos, by Sheldon Krimsky, 2000. The premise behind the EEH is that chemicals mimicking endocrine hormones can bind to receptors and thus can cause health problems in humans as well as other animals. Krimsky shows how this hypothesis first developed within the scientific community, in large part as a result of the persistence and insight of Theo Colborn. While working for the nonprofit Conservation Foundation in the 1980s, Colborn formulated the EEH, linking together evidence from several disparate sources: deleterious effects on wildlife exposed to pesticides, defects in babies whose mothers took the estrogen substitute diethylstilbestrol (DES) and controversial claims that human sperm is declining in quantity and quality.
Sources and book reviews
- Hormonal Chaos: The Scientific and Social Origin of the Environmental Endocrine Hypothesis, NCBI PMC1118410, British Medical Journal; 321(7259):516, BMJ 2000 Aug 19.
- The Case of the Deformed Frogs, americanscientist, July-August 2000.
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More DES DiEthylStilbestrol Resources
- DES studies on cancers and screening.
- DES studies on epigenetics and transgenerational effects.
- DES studies on fertility and pregnancy.
- DES studies on gender identity and psychological health.
- DES studies on in-utero exposure to DES and side-effects.
- DES studies on the genital tract.
- Papers on DES lawsuits.
- DES videos and posts tagged DES, the DES-exposed, DES victims.