1988 Study Abstract
During the last 14 years, several articles have given contradictory reports on prevalence rates of squamous cell neoplasia of the cervix and vagina in diethylstilbestrol (DES)-exposed progeny.
In 1984, the DES-Adenosis (DESAD) Project found that the incidence of cervical and vaginal intraepithelial neoplasia in DES-exposed daughters was twice as high as in a comparison group of unexposed women.
This was also associated with a higher rate of herpes simplex virus and human papillomavirus infections. Possible hypotheses on the etiology of the increased incidence of squamous neoplasia are discussed.
Sources and more information
- Development of cervical and vaginal squamous cell neoplasia as a late consequence of in utero exposure to diethylstilbestrol,
NCBI PMID: 2829071, Obstet Gynecol Surv. 1988 Jan;43(1):15-21.
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