Physical and psychological problems associated with exposure to diethylstilbestrol

Psychiatric disorders among DES-exposed persons, 1988

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Psychiatric disorders among DES-exposed persons are reportedly twice as common as for nonexposed persons, with anger, anxiety, low self-worth, identity confusion, and guilt the most frequent symptoms. the lightner.

1988 Study Abstract

The synthetic hormone diethylstilbestrol (DES) was widely prescribed between 1943 and 1971 to minimize pregnancy complications.

It has caused serious physical and psychological damage to the women who took it and to their offspring. DES-exposed mothers may suffer a higher incidence of breast cancer, their exposed daughters are at risk for reproductive tract cancers and infertility, and their exposed sons are more likely to have genital abnormalities and reproductive dysfunction.

Psychiatric disorders among DES-exposed persons are reportedly twice as common as for nonexposed persons, with anger, anxiety, low self-worth, identity confusion, and guilt the most frequent symptoms. The author describes therapeutic interventions designed to alleviate these problems.

Sources and more information
  • Physical and psychological problems associated with exposure to diethylstilbestrol (DES), Hospital & community psychiatry, NCBI PMID: 3276594, 1988 Jan.
  • Full study psychiatryonline, Volume 39 Issue 1, January 1988, pp. 73-77.
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