Abstract:
Recurrent pregnancy loss is a disease distinct from infertility, defined by two or more failed pregnancies. When the cause is unknown, each pregnancy loss merits careful review to determine whether specific evaluation may be appropriate. After three or more losses, a thorough evaluation is warranted. Although approximately 25% of all recognized pregnancies result in miscarriage, less than 5% of women will experience two consecutive miscarriages, and only 1% experience three or more. Couples who experience recurrent pregnancy loss may benefit from a medical evaluation and psychological support.
The American Society for Reproductive Medicine includes:
- Genetic/Chromosomal Causes
- Age
- Hormonal Abnormalities
- Metabolic Abnormalities
- Uterine Abnormalities
- Antiphospholipid Syndrome
- Thrombophilias
- Male factor
- Unexplained
No explanation is found in 50% to 75% of couples with recurrent pregnancy losses. Here’s an explanation: the chance of miscarriages increases if a women has been exposed to DES, synthetic estrogens, BPA, Endocrine Disruptors… ! ! !
A problem with the shape of a woman’s uterus might be a cause for pregnancy loss. Causes for abnormal shape of the uterus can be genetic or exposure before birth to medications such as diethylstilbestrol (DES).
The American Society for Reproductive Medicine, Revised 2016.
Full Patient Fact Sheet: What is recurrent pregnancy loss (RPL)?
Related posts
- Understanding why some Women have repeated Miscarriages.
- Women with Recurrent Miscarriages, a PLOSMedicine Study.
DES Daughters
DES daughters have a higher risk of recurrent miscarriages.
If you know or think you may have been exposed to DES it’s important to inform your doctor and gynaecologist.
- Are you a probable DES Daughter? See this Chart and establish how much Risk you face!.
- A Comparison of Pregnancy Experience in DES-exposed and DES-unexposed Daughters.
- Continued follow-up of Pregnancy Outcomes in #DiEthylStilbestrol-exposed Offspring.
More DES DiEthylStilbestrol Resources
- DES studies on cancers and screening.
- DES studies on epigenetics and transgenerational effects.
- DES studies on fertility and pregnancy.
- DES studies on gender identity and psychological health.
- DES studies on in-utero exposure to DES and side-effects.
- DES studies on the genital tract.
- Papers on DES lawsuits.
- DES videos and posts tagged DES, the DES-exposed, DES victims.
I had been told with my first husband that I couldn’t carry a child to term. I had 5 miscarriages with him. They thought it was the DES. I believe it was combination of my DES and my first husband.
But with my second husband, we had five children… all full term….two miscarriages, first two babies I had pre-term labor and was put on terbutiline (sp) for the last three months of my pregnancies. My last three, I had after I retired from the Navy and not one problem….no stress. I lost a fraternal twin with my last baby. My daughter survived, but lost her brother at eight weeks. I thought I had lost them both…but she hung in there till full term. My babies were not big.
Amy
thank you
How frustrating! This is not the only document around, published in the name of “science”, to have ignored DES as a contributory risk factor. It’s a disgrace.
Carol
indeed 🙁
ASRM has recently updated their fact sheet to include DES as a cause of recurrent pregnancy loss.
Excellent news and thank you so much for letting us know.
I have amended the post above, cheers 🙂
And in case you wish to meet on … Twitter,
best