Yes! desPLEX to prevent Abortion Miscarriage and Premature Labor…

A convincing sales pitch appeared in 1957, right in the middle of the thirty-three year period between 1938 and 1971 during which Diethylstilbestrol (DES) was prescribed regularly under various brand names

image of desplex advert
Although clinical trials in the 1950s demonstrated that it was ineffective for prevention of adverse pregnancy outcomes, it remained in use until 1971 in the United States and until the early 1980s in some other countries. There was no benefit with the use of diethylstilbestrol in preventing miscarriages. Both short and long-term adverse outcomes in exposed offsprings were demonstration of the harm that this intervention caused women and their offspring during its usage.

Yes! desPLEX to prevent abortion miscarriage and premature labor. Recommended for routine prophylaxis in ALL pregnancies! Ninety-six percent live delivery with desPLEX in one series of 1200 patients – bigger and stronger babies, too. No gastric or other side effects with desPLEX – in either high or low dosage.”

This convincing sales pitch appeared in 1957, right in the middle of the thirty-three year period between 1938 and 1971 during which Diethylstilbestrol (DES) was prescribed regularly under the brand names Estrosyn, Palestrol, Domestrol, and more.

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