The Consequences of Mass PreNatal Progestin Exposure, 1950s-70s

Worse than thalidomide?

The consequences of mass prenatal progestin exposure, 1950s-70s
Worse than Thalidomide?

When we think of prenatal drug disasters, we usually think of the sedative thalidomide, which caused horrific birth defects, and synthetic estrogen DES, which caused cancer and infertility in offspring, among other horrors.

Ignored, however, have been the downstream effects of the extensive use of progestin drugs in obstetric and fertility practice from the late 1950s through today. Progestins, not estrogens, were the most widely used anti-miscarriage drugs during several decades of practice that placed near-unquestioning faith in modern pharmaceuticals combined with near-nonexistent concern about impacts on the fetus. ”

Read Worse than thalidomide?
by Jill Escher, Autism Exposed

DES DiEthylStilbestrol Resources

The British Medical Community Approach to Drug Labelling, Diethylstilbestrol use, Public Awareness

Extract from: Meyler’s Side Effects of Endocrine and Metabolic Drugs

Meyler's Side Effects of Endocrine and Metabolic Drugs book cover image
The DES drug was prescribed until 1973 in the UK

In Britain the medical community was alerted to the risks by an editorial in the British Medical Journal in 1971, but it was only in 1973 that the Committee on Safety of Medicines advised against the use of Diethylstilbestrol during pregnancy. In Britain, drugs were commonly not labelled with information about their contents, nor with warning of risk until well into the 1990s, thus patients were kept in ignorance.
No measures have yet been taken in Britain to alert the public to the need for medical surveillance of women who have been exposed to Diethylstilbestrol in utero. It is estimated that in the U.S.A, the Netherlands, and France, diethylstilbestrol was given to over 5.3 million pregnant women, and it is known that it has been given to pregnant women in most parts of the world
. ”

Extract from: Meyler’s Side Effects of Endocrine and Metabolic Drugs
by Jeffrey K. Aronson.

More DES DiEthylStilbestrol Resources

Eli Lilly stops experimental Cancer Drug Enzastaurin Development

Lymphoma drug, Enzastaurin, fails In late-stage trial

Eli Lilly stops Development of Experimental #Cancer Drug #Enzastaurin
Eli Lilly made $27.7 Billion in Profits between 2003-2012 – sources HuffPolitics Blog

Eli Lilly said it will stop development of Enzastaurin experimental cancer drug after it failed in a late-stage trial to delay a worsening of symptoms in patients with lymphoma, but continues with late-stage trials of two other experimental cancer drugs.

Read Eli Lilly Lymphoma Drug, Enzastaurin, Fails In Late-Stage Trial HuffPost Healthy Living, 05/10/2013

All our posts tagged Eli Lilly – Big PharmaDrugs

The United States Trade Office placing India on their BlackList

India’s U.S. Drug Rulings Earn Trade Blacklist Spot From Obama Administration

The United States placed India on a special trade blacklist last week, a move some public health advocates said was retaliation for the country allowing generic versions of expensive drugs preferred by the U.S. government… The Office of the U.S. Trade Representative objected to aspects of India’s patent system in their latest report.

South African Media asking for ALL Medical Research Results to be known

Why researchers MUST publish ALL results of clinical trials

Call for all clinical trial results to be made known
Sir Iain Chalmers says let’s make all research results public

South Africans participating in clinical trials should demand that results are published ” says Cochrane Collaboration founder Sir Iain Chalmers.
Much of the world’s clinical research was wasteful and failed to tackle issues that were most important to patients ” Sir Iain told delegates at a conference hosted by the Medical Research Council (MRC).
Worse still, only 50% of the research was published, which meant doctors and patients were left in the dark about possible side effects, concealing evidence of potential possible harm from doctors and patients alike ” he said.

Find out more:

Are you thinking about buying Medicine online?

Find out what the FDA recommendations are

The FDA has a campaign called BeSafeRx: Know Your Online Pharmacy to raise awareness of the dangers of buying medicines from fake online pharmacies and to provide resources to help US consumers buy safely.

Here is what the FDA highlights in one of their their videos

About buying Medicine online

  • You may get a fake drug, with the wrong ingredients
  • Your condition may get worse
  • You may experience a bad reaction

About learning how to be Safe

  • Identify signs of a fraudulent pharmacy
  • Get a prescription
  • Get to know your online pharmacy and only buy from a legal one
  • Take medicine as directed

Some thoughts

  • Although there are many legitimate online pharmacies, others aren’t licensed in the United States — and some aren’t pharmacies at all. So while buying prescriptions online can save time and even money, it’s important to be selective about which sites to use. Even though I think it is an important campaign as a DES Daughter victim of the biggest drug scandal, I just find it slightly ironic … Whether you buy online or offline, is taking prescription drugs ever safe? Think twice before taking any prescription drugs and be aware of all the side effects.
  • Watch our DES Videos in English Playlist on YouTube.

Bad Science by Ben Goldacre lifts the lid on quack doctors, flaky statistics, evil pharma and more

How the scientific method works, and what to look for when presented with so-called “evidence”

Bad Science by @bengoldacre lifts the lid on quack doctors, flaky statistics, evil pharma and more
Bad Science Book by Ben Goldacre

How do we know if a treatment works, or if something causes cancer? Can the claims of homeopaths ever be as true – or as interesting as the improbable research into the placebo effect? Who created the MMR hoax? Do journalists understand science? Why do we seek scientific explanations for social, personal and political problems? Are alternative therapists and the pharmaceutical companies really so different, or do they just use the same old tricks to sell different types of pill? We are obsessed with our health. And yet – from the media’s ‘world-expert microbiologist’ with a mail-order PhD in his garden shed laboratory, via multiple health scares and miracle cures, to the million pound trial that Durham Council now denies ever existed – we are constantly bombarded with inaccurate, contradictory and sometimes even misleading information. Until now. Ben Goldacre masterfully dismantles the dodgy science behind some of the great drug trials, court cases and missed opportunities of our time, but he also goes further: out of the bulls—, he shows us the fascinating story of how we know what we know, and gives us the tools to uncover bad science for ourselves.

Ben Goldacre is Britain’s finest writer on the science behind medicine, and Bad Science is the UK Sunday Times top ten bestseller

More information

WebsiteAudibleAmazon – Reviews

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Ben GoldacreAll TrialsBad Pharma

Support the Thalidomide Survivors

Show Your Hand against Grünenthal

Give support to Thalidomide survivors by signing their ePetition.

UK Survivors of the Thalidomide tragedy have started a campaign called “Show your Hand” which is aimed at forcing Grunenthal to pay compensation to all its victims around the world.

More information:

Influence of Pharmaceutical Sales Reps in keeping patented Brands in Doctors’ Minds

Why do doctors prescribe the most costly drugs?

Why do doctors prescribe the most costly drugs?
Did our governments leave the education of our doctors to the pharmaceutical industry?

Selling pharmaceuticals is an extremely competitive business and companies know that they need to put their best face forward. That face is usually a smiling drug representative whose job it is to teach your physician about the newest medicines being produced today.
In Canada the drug industry spends roughly $3 billion per year marketing its products, two-thirds of which goes towards the salaries of the sales reps who visit our physicians regularly, and the drug samples they use to enhance their one-on-one learning sessions
. “

Read Why do doctors prescribe the most costly drugs?
by Alan Cassels, Feb 28, 2012.

Pharmaceutical Sales Reps not informing Doctors about promoted Drug Side-Effects in 60% of Visits

Doctors not informed of harmful effects of medicines during sales visits

Doctors not informed of harmful effects of medicines during sales visits
In Vancouver and Montreal, two-thirds of the promotional visits involved absolutely no mention of a drug’s potential harmful effects

Last month a study concerning the world of prescription drug information identified a new and potentially deadly hazard: the pharmaceutical sales rep visit. The study asked the question: When a drug sales rep has a private one-to-one conversation with a doctor, what kind of drug information does the physician actually receive? … The study found that in nearly 60 per cent of promotional visits, sales representatives failed to provide any information about common or serious side-effects of the promoted drug, and also failed to inform doctors about the types of patients who should not use the medicine…

Read Doctors not informed of harmful effects of medicines during sales visits

Read The sinister side-effects of drug marketing
by Alan Cassels, 22 Apr 2013