Make all medical research results public
A new campaign All trials registered, all results reported – supported by the Medical Research Council (publicly funded organisation in the UK dedicated to improving human health) – calls for the results of all clinical trials to be made public.
Sir Iain Chalmers, Coordinator of the James Lind Initiative, has strong words on researchers who hide trial results and ends his post by saying: “ If action is not taken urgently by research funders and regulators, information on what was done and what was found in trials could be lost forever, leading to bad treatment decisions, unnecessary repetition of trials, and missed opportunities for good medical practice. ”
Read Make all research results public, insight, 4 April 2013.
#AllTrials website and donation site.
How Drug Companies Mislead Doctors and Harm Patients
Last February 18th, 2013, at Town Hall Seattle, Dr. Ben Goldacre talked about his book, Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients, in which he discusses the influence of the pharmaceutical industry on the global healthcare system and argues that pharmaceutical companies hide negative studies and use questionable testing and intensive lobbying to get what they want, regardless of whether the drugs they produce are good for patients. Watch the video (1 hour, 26 minutes) .
More about Ben Goldacre
DES Videos in English – Diethylstilboestrol YT video channel.
Fetal Engineering Very Dangerous Experiment
Science Daily post Dangerous Experiment in Fetal Engineering analyses Prenatal Dexamethasone for Congenital Adrenal Hyperplasia published in the Journal of Bioethical Inquiry using extensive Freedom of Information Act findings to detail an extremely troubling off-label medical intervention employed in the U.S. on pregnant women to intentionally engineer the development of their fetuses for sex normalization purposes.
2012 Study Abstract
Following extensive examination of published and unpublished materials, we provide a history of the use of dexamethasone in pregnant women at risk of carrying a female fetus affected by congenital adrenal hyperplasia (CAH). This intervention has been aimed at preventing development of ambiguous genitalia, the urogenital sinus, tomboyism, and lesbianism. We map out ethical problems in this history, including: misleading promotion to physicians and CAH-affected families; de facto experimentation without the necessary protections of approved research; troubling parallels to the history of prenatal use of diethylstilbestrol (DES); and the use of medicine and public monies to attempt prevention of benign behavioral sex variations. Critical attention is directed at recent investigations by the U.S. Food and Drug Administration (FDA) and Office of Human Research Protections (OHRP); we argue that the weak and unsupported conclusions of these investigations indicate major gaps in the systems meant to protect subjects of high-risk medical research.
This is insane ! This shows NOTHING has been learned from the thalidomide and DES experiences.
…”utilement employé dans: menaces d’avortement”. ! ? ! ?
Le Distilbène DES, en savoir plus
Why do so many doctors still think they are invincible to Big Pharma’s influence?
” The bottom line for any for-profit company is to sell their product, and since the pharmaceutical industry can’t sell drugs directly to patients, they convince doctors to prescribe them.
The more a doctor sees or hears the name of a drug, whether through drug reps, brochures or seeing the name on stationery, the more likely the drug is to be prescribed. ”
Read Doctors Are Under the Influence of Pharma Drugs by Ritika Goel, 04/02/2013.
Pay-to-delay deals costly for the general public
” … When a company’s patent on a brand-name drug expires, other companies are free to make generic versions of the same drug… Often times, there are legal disputes between brand-name drug manufacturers and generic-drug companies. It’s increasingly common for this litigation to end with out-of-court settlements in which patentholders pay potential competitors to delay the introduction of generics.
That’s pay-to-delay… ”
Read PD Editorial: Pay-to-delay deals costly for consumers.
Read How ‘Pay for Delay’ Keeps Us Paying More for Prescription Drugs.
How Drug Companies mislead Doctors and harm Patients
When a new drug gets tested, the results of the trials should be published for the rest of the medical world — except much of the time, negative or inconclusive findings go unreported, leaving doctors and researchers in the dark. In this impassioned talk, Ben Goldacre explains why these unreported instances of negative data are especially misleading and dangerous.
More about Ben Goldacre
DES Videos in English – Diethylstilboestrol YouTube video channel.
The corruption in the pharmaceutical industry and in America’s healthcare system poses a far greater threat to the health, safety and welfare of Americans today than terrorism
Pharma Times Online, 2013
The video, shot during the debate at the Royal Institution last month, shows the author of Bad Science and Bad Pharma debate the notion ‘Pharma is not getting its act together’ with the chief executive of the ABPI.
More info and Videos
Doctors, not drugmakers, must warn patients of risks, court says
” The Supreme Court of Texas has ruled that pharmaceutical manufacturers are not responsible for conveying drug risks to patients, even when the drugmakers advertise their products directly to consumers… Health professionals said the decision creates greater liability for doctors and removes necessary responsibility from drugmakers after medication mishaps… drugmakers are not completely without liability if a patient is injured by a drug. If incorrect information is passed to physicians, a manufacturer still can be held liable… But drug companies cannot be sued for failing to provide drug warning information directly to a patient…” .
Read Court: Doctors, not drugmakers, must warn patients of risks
by Alicia Gallegos, uly 16, 2012.