Endocrine disruptors are everywhere…

How Chemicals affect us…

Researchers warn that endocrine disruptors can trigger hormonal changes in the body that may not show up for decades.

How Chemicals Affect Us by Nicholas Kristof

Scientists are observing with increasing alarm that some very common hormone-mimicking chemicals can have grotesque effects.

Great article! DES was not banned though as mentioned in the article … I wish it had been banned …
Read How Chemicals Affect Us by Nicholas Kristof, MAY 2, 2012.

DES Stories

Faces and Voices of People exposed to Diethylstilbestrol

DES Stories - Faces and Voices of People Exposed to Diethylstilbestrol
Faces and Voices of People Exposed to Diethylstilbesterol

A tribute to the millions of lives upended by exposure to DES, diethylstilbestrol, synthetic estrogen, toxic chemical, and carcinogenic prescription drug. In photographic portraits and interviews, DES daughters, mothers, and sons tell, in their own voice, what it’s like to be DES-exposed. Today the DES story continues to unfold as research brings new findings to light. DES Stories rings with daring honesty—and points to broader concerns about the effects of endocrine-disrupting chemicals.

by Margaret Lee Braun and Nancy M. Stuart

More DES DiEthylStilbestrol Resources

FDA Close to BPA Decision Crucial for Health of Poor Children

Hormonally active chemicals such as BPA have no place in our kids’ life

FDA Close To BPA Decision Crucial For Health Of Poor ChildrenA new study by scientists from Boston University found a strong link between the burden of BPA and poverty

Read FDA Close To BPA Decision Crucial For Health Of Poor Children

2012 Study Abstract

Bisphenol A (BPA) and polyfluoroalkyl chemicals (PFCs) are suspected endocrine disrupting compounds known to be ubiquitous in people’s bodies. Population disparities in exposure to these chemicals have not been fully characterized.

We analyzed data from the 2003-2006 National Health and Nutrition Examination Survey. Using multivariable linear regression we examined the association between urinary concentrations of BPA, serum concentrations of four PFCs, and multiple measures of socioeconomic position (SEP): family income, education, occupation, and food security. We also examined associations with race/ethnicity.

All four PFCs were positively associated with family income, whereas BPA was inversely associated with family income. BPA concentrations were higher in people who reported very low food security and received emergency food assistance than in those who did not. This association was particularly strong in children: 6-11 year-olds whose families received emergency food had BPA levels 54% higher (95% CI, 13 to 112%) than children of families who did not. For BPA and PFCs we saw smaller and less consistent associations with education and occupation. Mexican Americans had the lowest concentrations of any racial/ethnic group of both types of chemicals; for PFCs, Mexican Americans not born in the U.S. had much lower levels than those born in the U.S.

People with lower incomes had higher body burdens of BPA; the reverse was true for PFCs. Family income with adjustment for family size was the strongest predictor of chemical concentrations among the different measures of SEP we studied. Income, education, occupation, and food security appear to capture different aspects of SEP that may be related to exposure to BPA and PFCs and are not necessarily interchangeable as measures of SEP in environmental epidemiology studies. Differences by race/ethnicity were independent of SEP.

Sources Social disparities in exposures to bisphenol A and polyfluoroalkyl chemicals: a cross-sectional study within NHANES 2003-2006, Environmental Health 2012, 11:10 doi:10.1186/1476-069X-11-10.

Common chemicals from household products, cosmetics, medicines may be causing cancers and other issues

Phthalates, PCBs and parabens should be used with greater caution, claims environment agency

Household chemicals' 'cocktail effect' raises cancer concerns for watchdogThese chemicals are called ‘endocrine disruptors‘ and they interfere with our hormone system causing cancerous tumors, birth defects, and other developmental disorders. Diethylstilbestrol is the perfect example. They should be used with greater caution, says the Environment Agency !!!! Not good enough! They should be banned full stop.

Read Household chemicals’ ‘cocktail effect’ raises cancer concerns for watchdog from theguardian

Our stolen Future

The hardback edition, released March 1996

DES was just one of many new synthetic chemicals that promised to give us control over the forces of nature

Our Stolen Future
We should have known better!
You can’t mess with Mother Nature, and win …

A book by Dr. Theo Colborn, Dianne Dumanoski and Dr. John Peterson Myers

Read Our Stolen Future: Excerpts from Chapter 4, Hormone Havoc.

More DES DiEthylStilbestrol Resources

Can Exposure to Toxins Change Your DNA?

Toxicants cause ovarian disease across generations

Can Exposure to Toxins Change Your DNA?

Female rats rejected the males descended from a fungicide-administered pregnant rat, even three generations later…

Read Can Exposure to Toxins Change Your DNA?
motherjones, June 19, 2012.

More information:

    • Toxicants cause ovarian disease across generations, news.wsu.edu, May 2012.
    • Epigenetic Transgenerational Actions of Endocrine Disruptors and Male Fertility, sciencemag, 3 June 2005.
    • Transgenerational epigenetic imprints on mate preference, pnas, November 27, 2006.

Effets transgénérationnels des perturbateurs endocriniens: les leçons du DES

Endocrine Disruptors and Lessons from DES Diethylstilbestrol

Pour plus d’information sur la journée tenue à l’Assemblée Nationale le 10 Avril 2012 vous pouvez lire cet article: Les Perturbateurs Endocriniens publié le 26 Avril dernier.

Intervention du Dr Annie J. Sasco, Médecin épidémiologiste du cancer, sur le thème “Effets transgénérationnels des perturbateurs endocriniens: les leçons du DES” lors de la table-ronde organisée par WECF le 10 avril sur le thème “Perturbateurs endocriniens, effets et mécanismes d’action de la conception à la maturité”.

Le Distilbène DES, en savoir plus

Endocrine Disruptors: DES Lessons

On Tuesday 10th April 2012, the French National Assembly hosted a debate around the harmful effects of endocrine disruptors to convince governments to take action.  French and foreign Endocrine Disruptors (ED) specialists attended the event, gave presentations and discussed the many issues associated with ED.  Among them was Dr. Annie J. Sasco , Cancer epidemiologist, INSERM Research Director, University of Bordeaux, France,  who worked on the transgenerational effects of endocrine disruptors, more specifically those of DES: “I am very pessimistic. For 30 years, cancer has doubled in the world. The DES tragedy is not enough. Even though DES was registered in 1939 in Britain on the poisons’ list, and it had been proven it was ineffective for the prevention of miscarriage since 1953, nothing prevented this drug from being widely produced and prescribed. It has been recognized as a carcinogenic drug since 1974, and it is now proven to have effects on the third generation in terms of risk of cancer, including ovarian and genital malformation rate 18 times higher than normal. We’ve just banned Bisphenol A in baby bottles yet the risks were known since the 30s. Another example is hormone replacement therapy: its extended use to 10 years of treatment is associated with an increased risk of cancer. ”

You can find more information about this debate by reading this article published on April, 26th (approximate translation by Google).

More DES DiEthylStilbestrol Resources