Many children with bi-polar and ADHD symptoms can be helped without the use of dangerous off-label drugs

Let’s try to find ways to relieve illness without the use of drugs

Video by dr rapp, published on 22 February 2008.

Many children with bi-polar and ADHD symptoms can be helped without the use of dangerous off-label drugs.

There are fast, easy and inexpensive answers available.

Each individual is different and the treatment is rarely identical.

Dr. Doris Rapp has dedicated her life to identifying and providing simple solutions to these and other behavior problems.

Our challenge for physicians is to find fast, easy, safe, effective and inexpensive ways to heal.

Relationship of Air Pollution to Sleep Disruption

The Multi-Ethnic Study of Atherosclerosis (MESA) Sleep and MESA-Air Studies

High levels of air pollution over time may get in the way of a good night’s sleep, according to new research presented at the ATS 2017 International Conference. Image credit Craig Sunter.

2017 Study Abstract

Introduction
Exposure to air pollution is associated with cardiovascular mortality and pulmonary morbidity, including asthma, COPD, lower respiratory infections, and possibly sleep apnea. Although air pollution also may influence sleep quality through alterations in inflammatory or autonomic nervous system pathways, the relationship between air pollution and sleep has not been well studied. We evaluated the relationship between participant-level estimates of long-term ambient-derived traffic-related air pollution exposure with objective sleep fragmentation.

Methods
We analyzed data from a subpopulation of the Multi-Ethnic Study of Atherosclerosis (MESA) who participated in both MESA Sleep and AIR studies. Exposure to traffic related air pollutants (oxides of nitrogen) were estimated at participants’ homes using spatio-temporal models based on cohort-specific monitoring averaged for one and five years prior to sleep assessment. Objective sleep fragmentation was evaluated with wrist actigraphy recorded over seven 24 hour periods. We used multivariate logistic regression models to evaluate for an association of traffic related air pollution with low sleep efficiency (<88%) and increased wake after sleep onset (WASO; > 60 mins). We adjusted for socio-demographics, sleep apnea (AHI>15), short sleep duration (< 6 hrs) and residential socio-economic status (SES).

Results
MESA participants (n=1863) were an average age 68 (+/- 9) years, 46% male, 36% white, 24% Hispanic, 29% black and 12% Asian. A quarter of the sample had < 88% sleep efficiency and 11% had WASO > 60 mins. The highest quartile NO2 exposure level (> 23.7 ppb) over 5 years compared to the lowest (< 10 ppb) was associated with a 57% greater odds of low sleep efficiency in fully adjusted models with a significant test for trend (table 1). The highest quartile compared to the lowest quartile NO2/x average 1 and 5-years exposure levels were also associated with 71-91% greater odds of > 60min WASO.

Conclusions
Higher levels of traffic-related air pollution are associated with greater odds of objectively measured sleep disruption after adjusting for individual and residential socio-demographics. Further research is needed to identify the mechanisms and whether associations are attributable to oxides of nitrogen, traffic noise, other pollutants or environmental exposures that co-vary with traffic.

Environmental exposures start in the womb

Protecting Children from the Environment

Children, including adolescents, are exposed to a variety of hazards from the environments in which they live, learn and play.

Environmental exposures start in the womb, and can have effects throughout life.

Early exposure to environmental risks contributes to childhood cancers.

SOURCES

Environmental Risks and Children

Protecting Children from the Environment

A safe, healthy and protective environment is key to ensuring all children grow and develop normally and healthily. In 2015, reducing environmental risks could have prevented more than a quarter of the 5.9 million deaths of children under 5 years.

Children are particularly vulnerable to air pollution, hazardous chemicals, climate change, and inadequate water, sanitation and hygiene.

SOURCES

Adolescent boys and girls most vulnerable to endocrine disrupting chemicals

Identifying Subpopulations Vulnerable to the Thyroid-Blocking Effects of Perchlorate and Thiocyanate

Adolescents aged 12 to 21 years are two to three times more sensitive than the general population to common environmental contaminants that can disrupt thyroid function and therefore should have the latter checked, according to US researchers.

2017 Study Abstract

Context
Common environmental contaminants can disrupt normal thyroid function, which plays essential but varying roles at different ages.

Objective
To evaluate the relationship of perchlorate, thiocyanate, and nitrate, three sodium-iodide symporter (NIS) inhibitors, and thyroid function in different age-sex-stratified populations.

Design, Setting, Participants, and Intervention
This was a cross-sectional analysis of data from the 2009-2012 National Health and Nutrition Examination Surveys (NHANES) evaluating the exposure to perchlorate, thiocyanate, and nitrate in 3,151 participants aged 12-80.

Main Outcome Measure
Blood serum free thyroxine (FT4) as both a continuous and categorical variable. We also assessed blood serum thyroid stimulating hormone (TSH).

Results
Controlling for serum cotinine, BMI, total daily energy consumption, race/ethnicity, and poverty-to-income ratio, for each log unit increase in perchlorate, FT4 decreased by 0.03 ng/dL in both the general population (p=0.004) and in all women (p=0.005), and by 0.06 ng/dL in adolescent girls (p=0.029), corresponding to 4% and 8% decreases relative to median FT4, respectively. For each log unit increase thiocyanate, FT4 decreased by 0.07 ng/dL in adolescent boys (p=0.003), corresponding to a 9% decrease relative to median FT4, respectively.

Conclusions
Our results indicate that adolescent boys and girls represent vulnerable subpopulations to the thyroid-blocking effects of NIS symporter inhibitors. These results suggest a valuable screening and intervention opportunity.

Sources and Press Releases
  • Identifying Subpopulations Vulnerable to the Thyroid-Blocking Effects of Perchlorate and Thiocyanate, Oxford University Press, doi.org/10.1210/jc.2017-00046, 20 April 2017.
  • Teens Most Susceptible to Endocrine Disruption From Chemicals, medscape, April 27, 2017.
  • Image credit Meena Kadri.
About Endocrine Disruptors

Protecting Children from the Environment

Protecting Children from the Environment

Children, including adolescents, are exposed to a variety of hazards from the environments in which they live, learn and play.

More than 1 in 4 child deaths could be prevented by cleaning up the environment. Each year 1.7 million deaths of children under 5 years old are linked to the environment.

Early exposure to environmental risks contributes to childhood cancers.

SOURCES

Air Pollution and Children

Protecting Children from the Environment

Air pollution is the greatest environmental risk to children’s health.

Every year air pollution kills 570,000 children. With all the challenges children face, the air they breathe shouldn’t be one of them.

Exposure to air pollution may also increase children’s lifelong risk of heart disease, stroke and cancer.

SOURCES

Environment and human health

Human health and well‑being are intimately linked to environmental quality

Preface

Human health and well-being are intimately linked to environmental quality. This has been recognised for decades amongst policymakers in Europe, and most recently appears as a cornerstone in the European Commission’s proposal for the 7th Environment Action Programme. This report, produced jointly by the European Environment Agency and the European Commission’s Joint Research Centre, outlines a number of environmental issues with a direct influence on people’s health and well-being and is a follow-up and update to the 2005 EEA/JRC report.

In the 8 years that have passed, the political context of environment and health has evolved. As highlighted in EEA’s The European Environment — state and outlook 2010 the policy focus is increasingly shifting from single environmental pollution issues towards systemic challenges regarding the maintenance of ecosystem resilience and the delivery of ecosystem services to human society. Climate change is a good example with its combined impacts on food and water security, heat waves, flooding risks and potential spread of diseases.

Human health and well‑being are intimately linked to environmental quality. This report, produced jointly by the European Environment Agency (EEA) and the European Commission’s Joint Research Centre (JRC), outlines a number of environmental issues with a direct influence on people’s health and well-being.

Where problem detection and measures in the environment and health area have typically been based on dose-effect studies of individual polluting substances and stressors, this new report makes the case for a more integrated take on health issues, acknowledging the complex inter-linkages between resource-use patterns, environmental pressures, multiple exposures and disease burden, as well as the key role that social inequalities play.

It also touches upon emerging issues resulting from long-term environmental and socio-economic trends, such as climate change, lifestyle and consumption changes and the rapid uptake and application of new chemicals and technologies. As such, it complements the recent EEA publication Late lessons from early warnings; science, precaution and innovation, which makes a strong argument for precautionary science in political decision-making, allowing us to strike a better balance between using economic opportunities and avoiding disproportionate risks to the environment and human health and well-being.

Environment and health is not just ‘an aspect’ of environmental policy, it is at the heart of it. In fact, it is central to Europe’s ambition to move towards a Green Economy. With this report, taking stock of the most pertinent environment and health issues, and combining the expertise of our two institutes in environmental reporting and scientific research, we hope to contribute to this goal.

Overview
  1. Setting the scene
  2. Chemicals
  3. Outdoor air
  4. Indoor air
  5. Radon
  6. Water
  7. Noise
  8. Electromagnetic fields
  9. Ultraviolet radiation
  10. Nanotechnology
  11. Green spaces and the natural environment
  12. Climate change
  13. Analytical and policy considerations
More Information
Endocrine Disruptors

The potential downsides of long-term analgesic use

The Ibuprofen Risks You Need to Know

“Painkillers you can get without a prescription—like acetaminophen, as well as ibuprofen, naproxen, and other so-called non steroidal anti-inflammatory drugs (NSAIDs)—are generally pretty safe. That’s why they are available over the counter to relieve mild-to-moderate pain from headaches, sore muscles and achy joints.

But if they’re used more frequently, or over long periods of time, they may pose dangers to the heart, kidneys, bone and even hearing.”

… continue reading The Ibuprofen Risks You Need to Know on TIME Health, Apr 20, 2017. Image credit andrea.

Diet sodas and artificially sweetened soft drinks linked to brain damage

Diet drinks TRIPLE your risk of stroke and dementia – and are FAR more dangerous than drinks sweetened with sugar

Two new studies from the same research group have found that those who consume one or more sugary drinks per day showed more brain shrinkage on MRI scans and performed more poorly on memory tests.

The researchers also said these diet drink consumers were twice as likely to have Alzheimer’s dementia.

2017 Study Abstract

Background and Purpose
Sugar- and artificially-sweetened beverage intake have been linked to cardiometabolic risk factors, which increase the risk of cerebrovascular disease and dementia. We examined whether sugar- or artificially sweetened beverage consumption was associated with the prospective risks of incident stroke or dementia in the community-based Framingham Heart Study Offspring cohort.

Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia, stroke.ahajournals, doi.org/10.1161/STROKEAHA.116.016027, April 20, 2017.

Image credit m01229.

Methods
We studied 2888 participants aged >45 years for incident stroke (mean age 62 [SD, 9] years; 45% men) and 1484 participants aged >60 years for incident dementia (mean age 69 [SD, 6] years; 46% men). Beverage intake was quantified using a food-frequency questionnaire at cohort examinations 5 (1991–1995), 6 (1995–1998), and 7 (1998–2001). We quantified recent consumption at examination 7 and cumulative consumption by averaging across examinations. Surveillance for incident events commenced at examination 7 and continued for 10 years. We observed 97 cases of incident stroke (82 ischemic) and 81 cases of incident dementia (63 consistent with Alzheimer’s disease).

Results
After adjustments for age, sex, education (for analysis of dementia), caloric intake, diet quality, physical activity, and smoking, higher recent and higher cumulative intake of artificially sweetened soft drinks were associated with an increased risk of ischemic stroke, all-cause dementia, and Alzheimer’s disease dementia. When comparing daily cumulative intake to 0 per week (reference), the hazard ratios were 2.96 (95% confidence interval, 1.26–6.97) for ischemic stroke and 2.89 (95% confidence interval, 1.18–7.07) for Alzheimer’s disease. Sugar-sweetened beverages were not associated with stroke or dementia.

Conclusions
Artificially sweetened soft drink consumption was associated with a higher risk of stroke and dementia.

2017 Study Abstract

Sugary beverage intake and preclinical Alzheimer’s disease in the community, alzheimersanddementia, dx.doi.org/10.1016/j.jalz.2017.01.024, March 05, 2017.

Introduction
Excess sugar consumption has been linked with Alzheimer’s disease (AD) pathology in animal models.

Methods
We examined the cross-sectional association of sugary beverage consumption with neuropsychological (N = 4276) and magnetic resonance imaging (N = 3846) markers of preclinical Alzheimer’s disease and vascular brain injury (VBI) in the community-based Framingham Heart Study. Intake of sugary beverages was estimated using a food frequency questionnaire.

Results
Relative to consuming less than one sugary beverage per day, higher intake of sugary beverages was associated with lower total brain volume (1–2/day, β ± standard error [SE] = −0.55 ± 0.14 mean percent difference, P = .0002; >2/day, β ± SE = −0.68 ± 0.18, P < .0001), and poorer performance on tests of episodic memory (all P < .01). Daily fruit juice intake was associated with lower total brain volume, hippocampal volume, and poorer episodic memory (all P < .05). Sugary beverage intake was not associated with VBI in a consistent manner across outcomes.

Discussion
Higher intake of sugary beverages was associated cross-sectionally with markers of preclinical AD.