Scientists critical of EU chemical policy found to have industry ties
Alexis Sobel Fitts, Editor for CJR.org confirms Stéphane Horel and Brian Bienkowski deserve a laurel for their article investigating a group of scientists who authored a controversial editorial condemning a proposed regulatory policy for endocrine disruptors.
Indeed the two EHN reporters chronicled the scientists’ financial and political affiliations – weaving a comprehensive story of the influences behind science policy.
What is this about?
Seventeen scientists who have criticized plans in Europe to regulate endocrine-disrupting chemicals have past or current ties to regulated industries. An investigation by Environmental Health News reveals that of 18 toxicology journal editors who signed a controversial editorial, 17 have collaborated with the chemical, pharmaceutical, cosmetic, tobacco, pesticide or biotechnology industries. Some have received research funds from industry associations, while some have served as industry consultants or advisors. The stakes are high in the controversy because it involves the European Union’s strategy to regulate hormone-altering chemicals – the first attempt in the world to do so. The new rules would have sweeping, global ramifications because all companies that sell a variety of products in Europe would have to comply.
Call for ban on endocrine disrupting pesticides in Europe
In this short video clip, Lisette van Vliet (HEAL) and Hans Muilerman (PAN Europe) explain why endocrine disrupting pesticides and other endocrine disrupting chemicals (EDCs) in Europe should be banned, the goals of the multi NGO ‘EDC Free Campaign‘ and urge organisations to join them.
HEAL and PAN Europe are members of the EDC Free campaign, a coalition of public interest groups representing more than 25 organisations across Europe working to raise public awareness and urge quicker governmental action on hormone disrupting chemicals.
ACOG Report: Exposure to Toxic Environmental Agents
Americans are exposed daily to environmental chemicals that could harm reproductive health, the nation’s largest groups of obstetricians and fertility specialists said Monday. Their report urges doctors to push for stricter environmental policies to better identify and reduce exposure to chemicals that prove truly risky.
Reducing exposure to toxic environmental agents is a critical area of intervention for obstetricians, gynecologists, and other reproductive health care professionals. Patient exposure to toxic environmental chemicals and other stressors is ubiquitous, and preconception and prenatal exposure to toxic environmental agents can have a profound and lasting effect on reproductive health across the life course. Prenatal exposure to certain chemicals has been documented to increase the risk of cancer in childhood; adult male exposure to pesticides is linked to altered semen quality, sterility, and prostate cancer; and postnatal exposure to some pesticides can interfere with all developmental stages of reproductive function in adult females, including puberty, menstruation and ovulation, fertility and fecundity, and menopause. Many environmental factors harmful to reproductive health disproportionately affect vulnerable and underserved populations, which leaves some populations, including underserved women, more vulnerable to adverse reproductive health effects than other populations. The evidence that links exposure to toxic environmental agents and adverse reproductive and developmental health outcomes is sufficiently robust, and the American College of Obstetricians and Gynecologists and the American Society for Reproductive Medicine join leading scientists and other clinical practitioners in calling for timely action to identify and reduce exposure to toxic environmental agents while addressing the consequences of such exposure.
Evidence de perturbations hormonales chez des ouvriers exposés, dans le cadre professionnel, aux phtalates
Une étude parue en mars 2012 sur le site de la revue britannique Human Reproduction met en évidence que l’exposition des testicules de l’homme adulte aux phtalates – un plastifiant – entraîne une inhibition de la production de l’hormone masculine, la testostérone. Jusqu’ici, un tel effet n’avait été constaté que sur les testicules de fœtus humain ou chez le rongeur.
Les perturbateurs endocriniens : qu’est ce que c’est ?
Les phtalates : où les trouve-t-on ?
Les perturbateurs endocriniens : quel impact sur notre santé ?
Quelle législation souhaitable ?
Omniprésents dans notre quotidien les phtalates soulèvent depuis longtemps de nombreuses préoccupations et sont devenus emblématiques du débat autour de Reach, la nouvelle réglementation chimique communautaire. C’est aujourd’hui pour leur caractère de perturbateurs endocriniens, et au vu des données nouvelles, que l’action réglementaire est plus que jamais nécessaire sur l’ensemble de cette famille de substances.
Plastics Derived Endocrine Disruptors (BPA, DEHP and DBP) Induce Epigenetic Transgenerational Inheritance of Obesity, Reproductive Disease and Sperm Epimutations
Environmental compounds are known to promote epigenetic transgenerational inheritance of adult onset disease in subsequent generations (F1–F3) following ancestral exposure during fetal gonadal sex determination. The current study was designed to determine if a mixture of plastic derived endocrine disruptor compounds Bisphenol-A (BPA), bis(2-ethylhexyl)phthalate (DEHP) and dibutyl phthalate (DBP) at two different doses promoted epigenetic transgenerational inheritance of adult onset disease and associated DNA methylation epimutations in sperm. Gestating F0 generation females were exposed to either the “plastics” or “lower dose plastics” mixture during embryonic days 8 to 14 of gonadal sex determination and the incidence of adult onset disease was evaluated in F1 and F3 generation rats. There were significant increases in the incidence of total disease/abnormalities in F1 and F3 generation male and female animals from plastics lineages. Pubertal abnormalities, testis disease, obesity, and ovarian disease (primary ovarian insufficiency and polycystic ovaries) were increased in the F3 generation animals. Kidney and prostate disease were only observed in the direct fetally exposed F1 generation plastic lineage animals. Analysis of the plastics lineage F3 generation sperm epigenome previously identified 197 differential DNA methylation regions (DMR) in gene promoters, termed epimutations. A number of these transgenerational DMR form a unique direct connection gene network and have previously been shown to correlate with the pathologies identified. Observations demonstrate that a mixture of plastic derived compounds, BPA and phthalates, can promote epigenetic transgenerational inheritance of adult onset disease. The sperm DMR provide potential epigenetic biomarkers for transgenerational disease and/or ancestral environmental exposures.
The chemicals Bisphenol-A (BPA) and DiEthyHexylPhthalate (DEHP, a phthalate) are linked to obesity and insulin resistance in adolescents in two new studies, but the findings cannot yet answer whether the hotly debated hormone-like compounds are causing the negative health effects they are linked with, experts say.
Scientists Puzzle Over Declining Sperm Counts; a ‘Crisis’ or Not Enough Data?
Are today’s young men less fertile than their fathers were?
A recent study in France found that the sperm concentration of men decreased by nearly one-third between 1989 and 2005.
This follows the findings of several other European health studies that have found that over the past 15 years or so, the sperm counts of healthy men ages 18 to 25 have significantly decreased.
A recent study in France found that the sperm concentration of men decreased by nearly one-third between 1989 and 2005. This follows the findings of several other European health studies that have found that over the past 15 years or so, the sperm counts of healthy men ages 18 to 25 have significantly decreased.
Possible causes suggested for the sperm crisis include exposure to pesticides or chemicals such as BPA, lifestyle changes in which men sit more than in decades past, obesity, drug and alcohol use, or even the chemicals and toxins that men are exposed to in the womb as babies.