Women can choose among several types of estrogen pills, which are equally effective at relieving menopausal symptoms. In a head-to-head comparison of two major forms of hormone replacement therapy, a more natural version of estrogen proved less dangerous to the heart than a synthetic one – a patented drug marketed as Premarin.
Read Less Blood Clot Risk Linked to Estradiol Than to Premarin Pills, Science News, 30 Sept 2013.
Read Synthetic Estrogens Pose Greater Clot Risk Than Natural Forms of Hormone, by Alexandra Sifferlin, 1 Oct 2013.
Sources: Lower Risk of Cardiovascular Events in Postmenopausal Women Taking Oral Estradiol Compared With Oral Conjugated Equine Estrogens, JAMA, 30 Sept 2013.
More about estrogens and hormone replacement therapy.