DES Transgenerational Neurodevelopmental Deficits, 2018 Study

Collaborative on Health and the Environment Webinar, 20 March 2019

Dr. Marianthi-Anna Kioumourtzoglou, Assistant Professor in the Department of Environmental Health Sciences at Columbia University Mailman School of Public Health, describes the study Association of Exposure to Diethylstilbestrol During Pregnancy With Multigenerational Neurodevelopmental Deficits design, statistical analyses, and findings.

References

DES DIETHYLSTILBESTROL RESOURCES

Financial toxicity: cancer treatment’s side effect

The shock and anxiety of a cancer diagnosis can be followed by a second jolt: the astronomical price of cancer drugs

Presented by Arjun Rajagopalan,
uploaded on SlideShare. Watch it full screen.

The mechanism by which a drug’s market price is fixed is opaque and mostly arbitrary. Medical research, particularly new drug discovery, is a very expensive endeavour; the drug industry uses this argument to price new drugs at levels that are breathtakingly high. With the backing of currently enforced patent protection laws, drug companies can insulate themselves against market forces that are operational in most other consumer markets where competition assures reasonable prices. The Indian drug industry which used to pride itself on its ability to reverse engineer and deliver generics substitutes at low prices, can no longer indulge in this tactic.

Cancer treatment is a large area of interest for drug research. Unlike other noncommunicable diseases like hypertension, diabetes and the like, patients with a diagnosis of cancer are usually keen to seek the best available treatments. Newer generations of cancer drugs are priced at astounding figures. Treatment costs can exceed 100,000 US dollars a year. Even for those in wealthy, developed nations, the burden can lead to far reaching domains: a complication that has been labeled as “financial toxicity”.

Distilbène : quelles leçons sociologiques ?

Une expérience médicale et sociale des perturbateurs endocriniens

Programme National de recherche sur les Perturbateurs Endocriniens – Colloque de restitution du 12 avril 2010 – Rennes.

Environmental Endocrine Disruption Crisis of Epidemic Proportions

AutismOne Conference 2017

Presented by Leslie Carol Botha, WHE,
uploaded on SlideShare. Watch it full screen.

Endocrine Disruptors

What Does the Future Hold for Autism Families?

Slides from the Autism in the Family Conference, February 2017

Presentation from the Autism in the Family Conference.

In Summary
  • Panic we’re not faking
  • Kool-aid—no more partaking
  • Policy we’ll be shaking
  • “i”nstitutions we creating
  • Spectrum needs some breaking
  • Smarter science is in the making

Time Bomb: a Journey into Old Exposures, Gametic Glitches, and the Autism Explosion

Slides from Society for Neuroscience Wonder, February 2017

This presentation to a student-run chapter of SFN explained the history and science behind the “Time Bomb” hypothesis of autism.

DES DiEthylStilbestrol Resources

Energy and Air Pollution

IEA presentation to the press, London 27 June 2016

  • Around 6.5 million premature deaths each year can be attributed to air pollution.
  • Energy production and use are by far the largest man-made sources of air pollutants.
  • Technologies to tackle air pollution are well known.
  • Small increase in energy investment could cut premature deaths from air pollution in half by 2040.

Sources

DES Update CDC 2003 Presentation for Clinicians and Nurses

Author: Jeffrey Goldberg, MD Louisville Oncology Associates, Kentucky

Developed in collaboration with the Centers for Disease Control and Prevention, Centers of Excellence in Women’s Health (Department of Health and Human Services) for CDC’s DES Update.

Sources – CDC

More DES DiEthylStilbestrol Resources

Fracking Chemicals Disrupt Hormone Function

Estrogen and Androgen Receptor Activities of Hydraulic Fracturing Chemicals and Surface and Ground Water in a Drilling-Dense Region

University of Missouri researchers have discovered that an oil and natural gas drilling technique called hydraulic fracturing uses chemicals that can disrupt the body’s hormones. The researchers found that the endocrine-disrupting chemicals used in the process could interfere with a class of hormones that includes testosterone and estrogen.

Sources:
  • MU Researchers Find Fracking Chemicals Disrupt Hormone Function, MU School of Medicine, News.
  • Estrogen and Androgen Receptor Activities of Hydraulic Fracturing Chemicals and Surface and Ground Water in a Drilling-Dense Region, MU School of Medicine, Endocrinology, 2013.
  • Watch it full screen or via SlideShare.
  • Meet DES Daughter Network on SlideShare.

Increasing Trends in Male Reproductive Disorders, Environmental Exposures, Implications for Human Health

Half of all young men’s semen quality does not meet the reference standard of the World Health Organization

On this call, Dr. Skakkebaek presented his concerns about increasing trends in male reproductive disorders, including the significant global increase in incidence of germ cell tumors. He and colleagues from all over the world demonstrated that over half of all young men’s semen quality does not meet the reference standard of the World Health Organization.

Dr. Skakkebaek presented evidence linking testicular cancer, poor semen quality, childlessness, and rapidly decreasing fertility rates. He showed how there is little doubt that environmental factors, most likely associated with modern lifestyles, have – in a broad sense – had an adverse influence on male reproductive health. He and his group are examining a fundamental role that exposure to endocrine-disrupting chemicals may play in these trends, trends that in a few decades will result in decreasing populations in industrialized countries, and believes collaborative research is required to identify the causes of these adverse trends.

Sources and more information