Why prescription drugs are now the third leading cause of death and the pharmaceutical manufacturers dominance of mental healthcare

James Moore interviews Professor Peter Gøtzsche, Nordic Cochrane Centre Director, 2017

James Moore was keen to talk to Prof. Peter Gøtzsche about his background in research, his views on antidepressant prescribing and how pharmaceutical manufacturers have influenced mental healthcare.

Overview

  • Professor Gøtzsche’s background in clinical trials within the Pharmaceutical industry.
  • How the pharmaceutical manufacturers were manipulating clinical trial data for their own gain.
  • How drug manufacturers have denied for more than 20 years that benzodiazepines and antidepressant drugs cause dependance.
  • How the UK drug regulator (MHRA) also denied this in 2003 at the same time that the World Heath Organisation reported that 3 antidepressants were in the top 30 list of drugs that create dependance.
  • That surveys of patients show that between 50% and 66% of those taking antidepressants experience dependance.
  • The similarities between the pharmaceutical industry and the tobacco industry.
  • That stopping an antidepressant suddenly can be very dangerous.
  • How prescription drugs have become the third leading cause of death behind heart disease and cancer.
  • How pharmaceutical manufacturers have used their power and influence to the detriment of patient safety.
  • That the best science shows that there is no doubt that psychiatric drugs have killed millions of people over the years.
  • How psychotherapy is shown to reduce the risk of suicide but instead we prescribe pills that increase the suicide risk for all ages of patients.
  • That the chemical imbalance lie is still being propagated amongst psychiatrists even thought here is no scientific evidence whatsoever so support it.
  • How psychiatric drugs should be used for acute/emergency situations only.
  • That the medication centred approach of psychiatry does more harm than good.
  • How patients should avoid psychiatric drugs unless they are used for a very short time or that the patient really feels that they need them.
  • That when you look at the randomised controlled trials, there is a large risk of bias in these trials and that antidepressant efficacy has been overstated.
  • That the Cochrane Collaboration undertook the most rigorous meta analysis ever undertaken of 131 trials involving 27,422 patients taking SSRI’s, this analysis showed that antidepressants do not have any meaningful effects and their harms outweigh any benefits there might be.

Sources

Glyphosate : perturbateur européen ?

Stéphane Horel et Yves Bertheau sont les invités de “Dimanche, et après ?”, octobre 2017

Par Raphaël Bourgois, via france culture.

Le débat européen autour du glyphosate met en lumière un ensemble complexe de rapports de forces entre différents acteurs. Au-delà de la question environnementale et sanitaire, ce sont les relations qu’entretiennent science, industrie et politique qui doivent être questionnées.

En Savoir Plus

An Investigation
  1. The Manufacture of a Lie.
  2. A Denial of the State of the Science.
  3. The Interference of the United States.
  4. The Discreet but Major Gift to the Pesticides Lobby.

Monsanto Papers, la saga continue …

Stéphane Horel, Stéphane Foucart et Nadine Lauverjat sont les invités de “cause à effets”, octobre 2017

Par Aurélie Luneau, via france culture.

À l’heure où la controverse sur le glyphosate soulève débats et questions de santé de publique, en Europe, et que les témoignages de victimes s’accumulent, que nous réservent encore les Monsanto Papers ?

En Savoir Plus

Distilbene, Levothyrox, Mediator, pilule contraceptive, vaccination obligatoire : comment regagner la confiance des patients

Bruno Toussaint est l’invité des Matins sur France Culture, septembre 2017

Par Guillaume Erner, via franceculture.fr.

Bruno Toussaint, ancien médecin généraliste et directeur éditorial de la revue Prescrire, parle de la confiance perdue en l’industrie pharmaceutique.

Retour sur les scandales sanitaires à répétition comme le Distilbène, le Médiator, le Levothyrox, en passant par la récente polémique sur les futures vaccinations obligatoires.

Le Distilbène DES, en savoir plus

Le Glyphosate est un Scandale Sanitaire, Politique, Economique, Humain et Social

Le Pr Charles Sultan est l’invité de 7h50 France Bleu Hérault, septembre 2017

Par Claire Moutarde, via francebleu.fr.

Pédiatre en endocrinologie, consultant au CHU de Montpellier, le Pr Charles Sultan qui se bat depuis 30 ans sur les effets des pesticides sur la santé des enfants dénonce la non interdiction du glyphosate.

Diagnostic tests : how to minimise harm

We must develop new diagnostic tests to tackle real health problems, not to generate them

New diagnostic tests: more harm than good, BMJ 2017;358:j3314,
06 January 2016.

Defenders against overdiagnosis, BMJ 2017;358:j3487, 20 July 2017.

Although new diagnostics may advance the time of diagnoses in selected patients, they will increase the frequency of false alarms, overdiagnosis, and overtreatment in others.

Bjorn Hofmann, professor of medical ethics at Norwegian University of Science and Technology, explains how to minimise harm. Press Play > to listen to the recording.

Key messages

  • Innovative technologies and ample venture capital are combining to produce new disease biomarkers and mobile monitoring devices
  • These new diagnostics are technologically advanced but do not automatically provide improvements in clinical care and population health
  • They have the potential to help some but also to increase the frequency of false alarms, overdiagnosis, and overtreatment in others
  • Excessive testing and false alarms may increase healthcare workload and shift clinicians’ focus towards the healthy
  • Misleading feedback at both the population and individual levels tends to favour further market growth
  • Clinicians must provide a strong counterbalance: educating patients, respecting baseline risk, thinking downstream, and expecting misleading feedback

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Que penser de la décision prise à Bruxelles pour tenter de définir les perturbateurs endocriniens ?

“On a franchi un pas significatif”… “On est dans une dynamique”…
~Patrick Levy~ , Médecin-Conseil de l’Union des Industries Chimiques

Votée hier par les Etats de l’UE, la définition des perturbateurs endocriniens hésite encore entre soumission aux lobbys et protection des populations européennes.

Source : Questions sur les perturbateurs endocriniens après leur vote européen, France Inter, Le téléphone sonne du mercredi 5 juillet 2017.

Les invités de l’émission LE TÉLÉPHONE SONNE

  • Stéphane Horel
    journaliste indépendante, documentariste
  • Pascal Durand
    Vice-président du groupe Verts-ALE au Parlement européen. Ancien avocat.
  • Patrick Levy
    Médecin-Conseil de l’Union des Industries Chimiques.

Quelques Tweets

Testing Medical Treatments : DiEthylStilbestrol

Testing Treatments Interactive, promoting better research for better healthcare

Audio published mid 2016 by Testing Treatments Interactive, promoting better research for better healthcare.

Press Play > to listen to the recording.

Sources and more information

Our SoundCloud Playlists
More DES DiEthylStilbestrol Resources

Over 50 years later, DES’ adverse effects continue

Women Exposed to DiEthylStilbestrol In Utero Face Ongoing Risks for Adverse Health Outcomes

October 8th, 2011, NEJM Journal Watch talked with two authors of the reportAdverse Health Outcomes in Women Exposed In Utero to Diethylstilbestrol“.

Press Play > to listen to the recording.

Sources and more information

Our SoundCloud Playlists
More DES DiEthylStilbestrol Resources

Medical error is the third leading cause of death in the US

Today in the US there are more medications, diagnoses and procedures than ever ; overtreatment is endemic

Medical error—the third leading cause of death in the US, The BMJ, dx.doi.org/10.1136/bmj.i2139, 03 May 2016.

Medical error is not included on death certificates or in rankings of cause of death.

Martin Makary and Michael Daniel assess its contribution to mortality and call for better reporting.
.
Press Play > to listen to the recording.

Medical error has been defined as an unintended act (either of omission or commission) or one that does not achieve its intended outcome, the failure of a planned action to be completed as intended (an error of execution), the use of a wrong plan to achieve an aim (an error of planning), or a deviation from the process of care that may or may not cause harm to the patient. Patient harm from medical error can occur at the individual or system level. The taxonomy of errors is expanding to better categorize preventable factors and events. We focus on preventable lethal events to highlight the scale of potential for improvement. “…

…Continue reading: Medical error—the third leading cause of death in the US, The BMJ, 03 May 2016. See also the responses.

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