Ms Liz Valente, Dr Ana Janic and Professor Andreas Strasser from the Molecular Genetics of Cancer division at the Walter and Eliza Hall Institute have been dissecting the processes that are controlled by p53, to discover how this protein can suppress cancer development. Their surprising results are published online today in the journal Cell Reports.
Find out more:
- Research Reveals Cancer-Suppressing Protein ‘Multitasks’
ScienceDaily.com, May 9, 2013
- p53 Efficiently Suppresses Tumor Development in the Complete Absence of Its Cell-Cycle Inhibitory and Proapoptotic Effectors p21, Puma, and Noxa
- p53 DNA Binding Cooperativity Is Essential for Apoptosis and Tumor Suppression In Vivo
- Discovery brings hope of new tailor-made anti-cancer agents